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Alendronate Drug Interactions

A total of 227 drugs are known to interact with alendronate.

  • 2 major drug interactions
  • 220 moderate drug interactions
  • 5 minor drug interactions

Show all medications in the database that may interact with alendronate.

Check for interactions

Type in a drug name to check for interactions with alendronate.

Most frequently checked interactions

View interaction reports for alendronate and the medicines listed below.

  • Advair Diskus (fluticasone / salmeterol)
  • Advil (ibuprofen)
  • Aspir 81 (aspirin)
  • Aspirin Low Strength (aspirin)
  • Calcium 600 D (calcium / vitamin d)
  • calcium citrate (Calcitrate, Citracal Kosher)
  • calcium / vitamin d (Calcium 600 D, Citracal + D, Caltrate 600+D, Oyster Shell Calcium with Vitamin D, Os-Cal Calcium+D3, Oyster Shell Calcium, Calcitrate with D, Os-Cal 500 Chewable, Oyst-Cal-D, Oysco 500 with D, Calcarb with D, Caltrate 600 with D Plus Soy, Calcio Del Mar, Citrus Calcium with Vitamin D, Dical-D, Caltro with Vitamin D, Oystercal-D, Osteocit D Plus, Citracal Petites, Citracal Maximum, Risacal-D, Wellesse Liquid Calcium with Vitamin D, Citracal Calcium Pearls, Os-Cal Extra D3, Oysco D, Calcet, O-Cal-D, Oyster-D, Oysco D with Calcium, Posture-D H/P, Dical Captabs, Dicalphos plus D, Caltrate Colon Health, Calvite P, Sedecal D, Chewable Calcium with Vitamin D, Citracal Regular 250 mg + D, Citracal Plus Heart Health, UPCal D, Citracal Regular, Citracal Slow Release 1200, Citracal Calcium Gummies, Caltrate Gummy Bites)
  • cholecalciferol (Vitamin D3, D3, Decara, Celebrate Vitamin D3 Quick-Melt, Maximum D3, D3-50, Wellesse Vitamin D3, Replesta, D2000, Ddrops, D 1000 IU, D-Vita Drops, Replesta Children's, Replesta NX, Thera-D 2000, Thera-D 4000, Carlson D, Bio-D-Mulsion, Bio-D-Mulsion Forte, Enfamil D-Vi-Sol, BProtected Pedia D-Vite, Delta D3, Thera-D Rapid Repletion, D400, D3-5, UpSpringbaby D)
  • Crestor (rosuvastatin)
  • Cymbalta (duloxetine)
  • Fish Oil (omega-3 polyunsaturated fatty acids)
  • ibandronate (Boniva)
  • ibuprofen (Advil, Motrin, IBU, Advil Liqui-Gels, Motrin IB, Proprinal, Advil Children's, Caldolor, Children's Motrin, Childrens Ibuprofen Berry, Motrin Childrens, Rufen, Ibuprofen PMR, Ibu-8, Motrin Pediatric, Menadol, Nuprin, Advil Junior Strength, Midol Maximum Strength Cramp Formula, Motrin Migraine Pain, Advil Migraine, PediaCare Children's IB Ibuprofen Pain Reliever/Fever Reducer, Ibu-6, NeoProfen, Ibu-Tab, Genpril, Haltran, IBU-200, Midol IB, Saleto-200, Q-Profen, Saleto-400, Saleto-600, Saleto-800, A-G Profen, Actiprofen, Addaprin, PediaCare Infants' IB Ibuprofen Pain Reliever/Fever Reducer, Ibu-4, Motrin Junior Strength, Motrin Infant Drops, Help I Have An Aching Body, Children's ElixSure IB, Advil Infant's Concentrated Drops, Cap-Profen, Advil Film-Coated)
  • levothyroxine (Synthroid, Levoxyl, Tirosint, Levothroid, Eltroxin, Levothyrox, Euthyrox, Unithroid, L Thyroxine Roche, Levo-T, Oroxine, Eutroxsig, Novothyrox, Tirosint-Sol, Levotabs, Levotec, Evotrox)
  • Lipitor (atorvastatin)
  • Lyrica (pregabalin)
  • Metoprolol Succinate ER (metoprolol)
  • Nexium (esomeprazole)
  • omeprazole (Prilosec, Prilosec OTC, Zegerid (Original Formulation), Omesec)
  • Plavix (clopidogrel)
  • ProAir HFA (albuterol)
  • ranitidine (Zantac, Zantac 150, Zantac 75, Zantac 300, Acid Reducer, Deprizine, Acid Relief, Zantac 25 mg EFFERdose, Berkley and Jensen Acid Reducer Maximum Strength, Zantac GELdose, Zantac 300 GELdose, Zantac EFFERdose, Acid Reducer Non-Prescription Strength, Zantac Injection, Sunmark Acid Reducer Maximum Strength, Zantac 150 EFFERdose, Acid Control 75, Taladine, Careone Acid Reducer, Equaline Heartburn Relief, Acid Control 150)
  • Spiriva (tiotropium)
  • Synthroid (levothyroxine)
  • teriparatide (Forteo)
  • Tylenol (acetaminophen)
  • Vitamin B12 (cyanocobalamin)
  • Vitamin C (ascorbic acid)
  • vitamin d
  • Vitamin D2 (ergocalciferol)
  • Vitamin D3 (cholecalciferol)

Alendronate alcohol/food interactions

There are 2 alcohol/food interactions with alendronate

Alendronate disease interactions

There are 7 disease interactions with alendronate which include:

Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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