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Alendronate Drug Interactions

A total of 227 drugs are known to interact with alendronate.

  • 2 major drug interactions
  • 220 moderate drug interactions
  • 5 minor drug interactions

Show all medications in the database that may interact with alendronate.

Check for interactions with alendronate

Type in a drug name and select a drug from the list.

Common medications checked in combination with alendronate

  • Advair Diskus (fluticasone / salmeterol)
  • Advil (ibuprofen)
  • Aspir 81 (aspirin)
  • Aspirin Low Strength (aspirin)
  • Calcium 600 D (calcium / vitamin d)
  • calcium citrate (Calcitrate, Citracal Kosher)
  • calcium / vitamin d (Calcium 600 D, Citracal + D, Caltrate 600+D, Oyster Shell Calcium with Vitamin D, Os-Cal Calcium+D3, Chewable Calcium with Vitamin D, Oysco 500 with D, Citracal Petites, Calcitrate with D, Calcio Del Mar, Oyster Shell Calcium, Calcarb with D, Citrus Calcium with Vitamin D, Citracal Maximum, Caltrate Gummy Bites, Oysco D, Oyst-Cal-D, Citracal Calcium Gummies, Citracal Calcium Pearls, Os-Cal Extra D3, O-Cal-D, Oystercal-D, Citracal Plus Heart Health, Citracal Regular, Citracal Slow Release 1200, Wellesse Liquid Calcium with Vitamin D, Os-Cal 500 Chewable, Dical-D, Calcet, Oyster-D, Caltro with Vitamin D, Oysco D with Calcium, Posture-D H/P, Dical Captabs, Dicalphos plus D, Caltrate 600 with D Plus Soy, Caltrate Colon Health, Calvite P, Sedecal D, Osteocit D Plus, Citracal Regular 250 mg + D, UPCal D, Risacal-D)
  • cholecalciferol (Vitamin D3, D3, Decara, Celebrate Vitamin D3 Quick-Melt, Replesta, Maximum D3, D2000, Delta D3, Thera-D 2000, Ddrops, D 1000 IU, D-Vita Drops, Replesta Children's, Replesta NX, Thera-D 4000, Carlson D, Bio-D-Mulsion, Bio-D-Mulsion Forte, Enfamil D-Vi-Sol, BProtected Pedia D-Vite, Thera-D Rapid Repletion, D400, D3-5, D3-50, UpSpringbaby D, Wellesse Vitamin D3)
  • Crestor (rosuvastatin)
  • Cymbalta (duloxetine)
  • Fish Oil (omega-3 polyunsaturated fatty acids)
  • ibandronate (Boniva)
  • ibuprofen (Advil, Motrin, IBU, Advil Liqui-Gels, Proprinal, Motrin IB, Children's Motrin, IBU-200, Advil Migraine, Ibu-8, Motrin Childrens, Nuprin, Motrin Migraine Pain, Ibuprofen PMR, NeoProfen, Caldolor, Advil Children's, Addaprin, Motrin Infant Drops, Advil Infant's Concentrated Drops, Rufen, Genpril, A-G Profen, Ibu-Tab, Haltran, Menadol, Midol IB, Saleto-200, Q-Profen, Saleto-400, Saleto-600, Saleto-800, Advil Junior Strength, Midol Maximum Strength Cramp Formula, Actiprofen, Childrens Ibuprofen Berry, PediaCare Infants' IB Ibuprofen Pain Reliever/Fever Reducer, Ibu-4, PediaCare Children's IB Ibuprofen Pain Reliever/Fever Reducer, Ibu-6, Motrin Junior Strength, Help I Have An Aching Body, Children's ElixSure IB, Cap-Profen, Motrin Pediatric, Advil Film-Coated)
  • levothyroxine (Synthroid, Levoxyl, Tirosint, Levothroid, Eltroxin, Unithroid, Levothyrox, Euthyrox, Levo-T, L Thyroxine Roche, Eutroxsig, Novothyrox, Oroxine, Tirosint-Sol, Levotabs, Levotec, Evotrox)
  • Lipitor (atorvastatin)
  • Lyrica (pregabalin)
  • Metoprolol Succinate ER (metoprolol)
  • Nexium (esomeprazole)
  • omeprazole (Prilosec, Prilosec OTC, Zegerid (Original Formulation), Omesec)
  • Plavix (clopidogrel)
  • ProAir HFA (albuterol)
  • ranitidine (Zantac, Zantac 150, Zantac 75, Zantac 300, Deprizine, Zantac Injection, Acid Reducer, Zantac 150 EFFERdose, Taladine, Zantac 25 mg EFFERdose, Berkley and Jensen Acid Reducer Maximum Strength, Zantac GELdose, Zantac 300 GELdose, Zantac EFFERdose, Acid Reducer Non-Prescription Strength, Acid Relief, Sunmark Acid Reducer Maximum Strength, Acid Control 75, Careone Acid Reducer, Equaline Heartburn Relief, Acid Control 150)
  • Spiriva (tiotropium)
  • Synthroid (levothyroxine)
  • teriparatide (Forteo)
  • Tylenol (acetaminophen)
  • Vitamin B12 (cyanocobalamin)
  • Vitamin C (ascorbic acid)
  • vitamin d
  • Vitamin D2 (ergocalciferol)
  • Vitamin D3 (cholecalciferol)

Alendronate alcohol/food interactions

There are 2 alcohol/food interactions with alendronate

Alendronate disease interactions

There are 7 disease interactions with alendronate which include:

Drug Interaction Classification

The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No information available.

Do not stop taking any medications without consulting your healthcare provider.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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