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Alendronate Drug Interactions

A total of 227 drugs are known to interact with alendronate.

  • 2 major drug interactions
  • 220 moderate drug interactions
  • 5 minor drug interactions

Show all medications in the database that may interact with alendronate.

Check for interactions

Type in a drug name to check for interactions with alendronate.

Most frequently checked interactions

View interaction reports for alendronate and the medicines listed below.

  • Advair Diskus (fluticasone / salmeterol)
  • Advil (ibuprofen)
  • Aspir 81 (aspirin)
  • Aspirin Low Strength (aspirin)
  • Calcium 600 D (calcium / vitamin d)
  • calcium citrate (Calcitrate, Citracal Kosher)
  • calcium / vitamin d (Calcium 600 D, Caltrate 600+D, Citracal + D, Oyster Shell Calcium with Vitamin D, Os-Cal Calcium+D3, Oysco 500 with D, Chewable Calcium with Vitamin D, Calcio Del Mar, Calcitrate with D, Oyster Shell Calcium, Citracal Petites, Oysco D, Calcarb with D, Citrus Calcium with Vitamin D, Citracal Maximum, Citracal Calcium Pearls, Os-Cal 500 Chewable, O-Cal-D, Oystercal-D, Caltrate 600 with D Plus Soy, Osteocit D Plus, Citracal Plus Heart Health, Risacal-D, Citracal Regular, Citracal Calcium Gummies, Os-Cal Extra D3, Dical-D, Calcet, Oyster-D, Oyst-Cal-D, Caltro with Vitamin D, Oysco D with Calcium, Posture-D H/P, Dical Captabs, Dicalphos plus D, Caltrate Colon Health, Calvite P, Sedecal D, Citracal Regular 250 mg + D, UPCal D, Citracal Slow Release 1200, Caltrate Gummy Bites, Wellesse Liquid Calcium with Vitamin D)
  • cholecalciferol (Vitamin D3, D3, Decara, Celebrate Vitamin D3 Quick-Melt, Replesta, Maximum D3, D2000, Delta D3, D3-50, D3-5, Wellesse Vitamin D3, Ddrops, D 1000 IU, D-Vita Drops, Replesta Children's, Replesta NX, Thera-D 2000, Thera-D 4000, Carlson D, Bio-D-Mulsion, Bio-D-Mulsion Forte, Enfamil D-Vi-Sol, BProtected Pedia D-Vite, Thera-D Rapid Repletion, D400, UpSpringbaby D)
  • Crestor (rosuvastatin)
  • Cymbalta (duloxetine)
  • Fish Oil (omega-3 polyunsaturated fatty acids)
  • ibandronate (Boniva)
  • ibuprofen (Advil, Motrin, IBU, Children's Motrin, Proprinal, Advil Liqui-Gels, Ibu-8, Motrin IB, Motrin Childrens, Rufen, Childrens Ibuprofen Berry, IBU-200, Ibuprofen PMR, Advil Migraine, Ibu-Tab, Genpril, Menadol, Advil Children's, Midol Maximum Strength Cramp Formula, Motrin Migraine Pain, Addaprin, Motrin Infant Drops, NeoProfen, Caldolor, Motrin Pediatric, Haltran, Midol IB, Saleto-200, Q-Profen, Saleto-400, Saleto-600, Saleto-800, A-G Profen, Nuprin, Advil Junior Strength, Actiprofen, PediaCare Infants' IB Ibuprofen Pain Reliever/Fever Reducer, Ibu-4, PediaCare Children's IB Ibuprofen Pain Reliever/Fever Reducer, Ibu-6, Motrin Junior Strength, Help I Have An Aching Body, Children's ElixSure IB, Advil Infant's Concentrated Drops, Cap-Profen, Advil Film-Coated)
  • levothyroxine (Synthroid, Levoxyl, Tirosint, Levothroid, Eltroxin, Euthyrox, Unithroid, Levothyrox, Eutroxsig, Levo-T, Oroxine, L Thyroxine Roche, Levotabs, Novothyrox, Tirosint-Sol, Levotec, Evotrox)
  • Lipitor (atorvastatin)
  • Lyrica (pregabalin)
  • Metoprolol Succinate ER (metoprolol)
  • Nexium (esomeprazole)
  • omeprazole (Prilosec, Prilosec OTC, Zegerid (Original Formulation), Omesec)
  • Plavix (clopidogrel)
  • ProAir HFA (albuterol)
  • ranitidine (Zantac, Zantac 150, Zantac 75, Zantac 300, Acid Reducer, Zantac 150 EFFERdose, Taladine, Zantac 25 mg EFFERdose, Berkley and Jensen Acid Reducer Maximum Strength, Deprizine, Zantac GELdose, Zantac 300 GELdose, Zantac EFFERdose, Acid Reducer Non-Prescription Strength, Zantac Injection, Acid Relief, Sunmark Acid Reducer Maximum Strength, Acid Control 75, Careone Acid Reducer, Equaline Heartburn Relief, Acid Control 150)
  • Spiriva (tiotropium)
  • Synthroid (levothyroxine)
  • teriparatide (Forteo)
  • Tylenol (acetaminophen)
  • Vitamin B12 (cyanocobalamin)
  • Vitamin C (ascorbic acid)
  • vitamin d
  • Vitamin D2 (ergocalciferol)
  • Vitamin D3 (cholecalciferol)

Alendronate alcohol/food interactions

There are 2 alcohol/food interactions with alendronate

Alendronate disease interactions

There are 7 disease interactions with alendronate which include:

Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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