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Platelet aggregation inhibitors

What are Platelet aggregation inhibitors?

Platelet aggregation inhibitors work in different places of the clotting cascade and prevent platelet adhesion, therefore no clot formation.

Aspirin, the most commonly used antiplatelet drug changes the balance between prostacyclin (which inhibits platelet aggregation) and thromboxane (that promotes aggregation). It irreversibly inhibits the enzyme cyclo-oxygenase, which leads to reduction in thromboxane synthesis in platelets and prostacyclin in vascular endothelial cells. The vascular endothelium recovers and can synthesize more prostacyclin but thromboxane synthesis only recovers after new platelets are formed.

Platelet aggregation inhibitors are used acutely in myocardial infarction, atrial fibrillation, following coronary bypass, angioplasty and stenting. It is also used as prophylaxis to prevent myocardial infarction and stroke.

List of Platelet aggregation inhibitors:

View by  Brand | Generic
Drug Name Avg. Rating Reviews
Brilinta (Pro)
Generic name: ticagrelor
3.5
77 reviews
Plavix (Pro)
Generic name: clopidogrel
7.4
60 reviews
Effient (Pro)
Generic name: prasugrel
7.0
20 reviews
Aggrenox (Pro)
Generic name: aspirin / dipyridamole
6.9
17 reviews
Pletal (Pro)
Generic name: cilostazol
7.7
5 reviews
Bayer Aspirin
Generic name: aspirin
4.2
5 reviews
Bayer Aspirin Extra Strength Plus
Generic name: aspirin
6.5
3 reviews
Arthritis Pain
Generic name: aspirin
10
2 reviews
St. Joseph Aspirin
Generic name: aspirin
10
1 review
Bayer Children's Aspirin
Generic name: aspirin
10
1 review
Yosprala (Pro)
Generic name: aspirin / omeprazole
No reviews
Vazalore
Generic name: aspirin
No reviews
Ticlid (Pro)
Generic name: ticlopidine
No reviews
Pravigard Pac (Pro)
Generic name: aspirin/pravastatin
8.0
No reviews
Persantine (Pro)
Generic name: dipyridamole
No reviews
Norwich Aspirin
Generic name: aspirin
No reviews
Miniprin
Generic name: aspirin
No reviews
Kengreal (Pro)
Generic name: cangrelor
No reviews
Halfprin
Generic name: aspirin
1.0
No reviews
Genacote
Generic name: aspirin
No reviews
Entercote
Generic name: aspirin
No reviews
Ecpirin
Generic name: aspirin
1.0
No reviews
Ecotrin
Generic name: aspirin
7.0
No reviews
Easprin
Generic name: aspirin
No reviews
Durlaza (Pro)
Generic name: aspirin
No reviews
Cablivi (Pro)
Generic name: caplacizumab
No reviews
Bayer Aspirin Regimen
Generic name: aspirin
10
No reviews
Aspirtab
Generic name: aspirin
No reviews
Aspiritab
Generic name: aspirin
No reviews
Aspir-Low
Generic name: aspirin
8.0
No reviews
Aspi-Cor
Generic name: aspirin
No reviews
Aspergum
Generic name: aspirin
8.0
No reviews
Ascriptin
Generic name: aspirin
No reviews
For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.