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Medications for Systemic Lupus Erythematosus

Other names: Disseminated Lupus Erythematosus; Lupus; SLE

A chronic, inflammatory autoimmune disorder that may affect many organ systems including the skin, joints, and internal organs.

Drugs used to treat Systemic Lupus Erythematosus

The following list of medications are in some way related to or used in the treatment of this condition.

Drug name Rating Reviews Activity ? Rx/OTC Pregnancy CSA Alcohol
Plaquenil 6.6 35 reviews
Rx N N

Generic name: hydroxychloroquine systemic

Drug class: antirheumatics, antimalarial quinolines

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

hydroxychloroquine 7.1 70 reviews
Rx N N

Generic name: hydroxychloroquine systemic

Brand name:  Plaquenil

Drug class: antirheumatics, antimalarial quinolines

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

Benlysta 7.7 49 reviews
Rx C N

Generic name: belimumab systemic

Drug class: selective immunosuppressants

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

prednisone 7.2 6 reviews
Rx C N

Generic name: prednisone systemic

Drug class: glucocorticoids

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

belimumab 7.7 50 reviews
Rx C N

Generic name: belimumab systemic

Brand name:  Benlysta

Drug class: selective immunosuppressants

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph

anifrolumab Rate Add review
Rx N

Generic name: anifrolumab systemic

Brand name:  Saphnelo

Drug class: selective immunosuppressants

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph

Saphnelo Rate Add review
Rx N

Generic name: anifrolumab systemic

Drug class: selective immunosuppressants

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Imuran 5.3 20 reviews
Rx D N

Generic name: azathioprine systemic

Drug class: antirheumatics, other immunosuppressants

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

azathioprine 5.2 23 reviews
Rx D N

Generic name: azathioprine systemic

Brand names:  Imuran, Azasan

Drug class: antirheumatics, other immunosuppressants

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

mycophenolate mofetil Off-label 8.5 4 reviews
Rx D N

Generic name: mycophenolate mofetil systemic

Drug class: selective immunosuppressants

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

Off-label: Yes

aspirin Rate Add review
Rx/OTC N N X

Generic name: aspirin systemic

Brand names:  Arthritis Pain, Aspergum, Bayer Aspirin, Easprin, Ecotrin, Ecpirin, Entercote, Genacote, Halfprin, Aspiritab, Aspirtab, Bayer Aspirin Extra Strength Plus, Norwich Aspirin, Vazalore …show all

Drug class: salicylates, platelet aggregation inhibitors

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

Kenalog-40 7.0 3 reviews
Rx C N

Generic name: triamcinolone systemic

Drug class: glucocorticoids

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

triamcinolone 7.0 3 reviews
Rx C N

Generic name: triamcinolone systemic

Brand names:  Kenalog-40, Clinacort, Kenalog-10

Drug class: glucocorticoids

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

Arthritis Pain Rate Add review
Rx/OTC N N X

Generic name: aspirin systemic

Drug class: salicylates, platelet aggregation inhibitors

For consumers: dosage, interactions, side effects

Aspergum Rate Add review
Rx/OTC N N X

Generic name: aspirin systemic

Drug class: salicylates, platelet aggregation inhibitors

For consumers: dosage, interactions, side effects

Bayer Aspirin Rate Add review
Rx/OTC N N X

Generic name: aspirin systemic

Drug class: salicylates, platelet aggregation inhibitors

For consumers: dosage, interactions, side effects

dexamethasone Rate Add review
Rx C N

Generic name: dexamethasone systemic

Brand names:  Dexamethasone Intensol, De-Sone LA, Dxevo, HiDex …show all

Drug class: glucocorticoids

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

Easprin Rate Add review
Rx N N X

Generic name: aspirin systemic

Drug class: salicylates, platelet aggregation inhibitors

For consumers: dosage, interactions, side effects

Ecotrin Rate Add review
Rx/OTC N N X

Generic name: aspirin systemic

Drug class: salicylates, platelet aggregation inhibitors

For consumers: dosage, interactions, side effects

Ecpirin Rate Add review
Rx/OTC N N X

Generic name: aspirin systemic

Drug class: salicylates, platelet aggregation inhibitors

For consumers: dosage, interactions, side effects

Entercote Rate Add review
Rx/OTC N N X

Generic name: aspirin systemic

Drug class: salicylates, platelet aggregation inhibitors

For consumers: dosage, interactions, side effects

Genacote Rate Add review
Rx/OTC N N X

Generic name: aspirin systemic

Drug class: salicylates, platelet aggregation inhibitors

For consumers: dosage, interactions, side effects

Halfprin Rate Add review
Rx/OTC N N X

Generic name: aspirin systemic

Drug class: salicylates, platelet aggregation inhibitors

For consumers: dosage, interactions, side effects

Aspiritab Rate Add review
Rx/OTC N N X

Generic name: aspirin systemic

Drug class: salicylates, platelet aggregation inhibitors

For consumers: dosage, interactions, side effects

Aspirtab Rate Add review
Rx/OTC N N X

Generic name: aspirin systemic

Drug class: salicylates, platelet aggregation inhibitors

For consumers: dosage, interactions, side effects

Alternative treatments for Systemic Lupus Erythematosus

The following products are considered to be alternative treatments or natural remedies for Systemic Lupus Erythematosus. Their efficacy may not have been scientifically tested to the same degree as the drugs listed in the table above. However there may be historical, cultural or anecdotal evidence linking their use to the treatment of Systemic Lupus Erythematosus.

Learn more about Systemic Lupus Erythematosus

Care guides

Symptoms and treatments

Legend

Rating For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).
Activity Activity is based on recent site visitor activity relative to other medications in the list.
Rx Prescription only.
OTC Over-the-counter.
Rx/OTC Prescription or Over-the-counter.
Off-label This medication may not be approved by the FDA for the treatment of this condition.
EUA An Emergency Use Authorization (EUA) allows the FDA to authorize unapproved medical products or unapproved uses of approved medical products to be used in a declared public health emergency when there are no adequate, approved, and available alternatives.
Pregnancy Category
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act (CSA) Schedule
M The drug has multiple schedules. The schedule may depend on the exact dosage form or strength of the medication.
U CSA Schedule is unknown.
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.