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Mycophenolate Mofetil Dosage

Medically reviewed by Drugs.com. Last updated on Nov 4, 2024.

Applies to the following strengths: 250 mg; 500 mg; 200 mg/mL

Usual Adult Dose for Organ Transplant - Rejection Prophylaxis


Comments:

Usual Geriatric Dose for Organ Transplant - Rejection Prophylaxis


Comments:

Usual Pediatric Dose for Organ Transplant - Rejection Prophylaxis

3 months to 18 years of age:
Oral Suspension: 600 mg/m2 orally 2 times a day up to a maximum of 2 grams per day

Comments:

Renal Dose Adjustments

CrCl less than 25 mL/min: Doses greater than 1 gm 2 times a day should be avoided

Liver Dose Adjustments

Data not available

Dose Adjustments

Precautions

US BOXED WARNINGS:


The US FDA requires a Risk Evaluation and Mitigation Strategy (REMS) for mycophenolate. It includes a medication guide and elements to assure safe use. For additional information: www.fda.gov/REMS.

CONTRAINDICATIONS:

Safety and efficacy have not been established in patients younger than 3 months.

Consult WARNINGS section for additional precautions.

Dialysis

Mycophenolic acid (the active metabolite) and the inactive glucuronide metabolite are not removed in significant amounts by hemodialysis.

Other Comments

Administration advice:


Storage requirements:

Reconstitution/preparation techniques:

Monitoring:
Advise patients to contact their healthcare provider if they develop any signs and symptoms of infections.

See also:

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.