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Mycophenolate Mofetil Dosage

Medically reviewed by Drugs.com. Last updated on Nov 13, 2022.

Applies to the following strengths: 250 mg; 500 mg; 200 mg/mL

Usual Adult Dose for Organ Transplant - Rejection Prophylaxis


Comments:

Usual Geriatric Dose for Organ Transplant - Rejection Prophylaxis


Comments:

Usual Pediatric Dose for Organ Transplant - Rejection Prophylaxis

3 months to 18 years of age:
Oral Suspension: 600 mg/m2 orally 2 times a day up to a maximum of 2 grams per day

Comments:

Renal Dose Adjustments

CrCl less than 25 mL/min: Doses greater than 1 gm 2 times a day should be avoided

Liver Dose Adjustments

Data not available

Dose Adjustments

Precautions

US BOXED WARNINGS:


The US FDA requires a Risk Evaluation and Mitigation Strategy (REMS) for mycophenolate. It includes a medication guide and elements to assure safe use. For additional information: www.fda.gov/REMS.

CONTRAINDICATIONS:

Safety and efficacy have not been established in patients younger than 3 months.

Consult WARNINGS section for additional precautions.

Dialysis

Mycophenolic acid (the active metabolite) and the inactive glucuronide metabolite are not removed in significant amounts by hemodialysis.

Other Comments

Administration advice:


Storage requirements:

Reconstitution/preparation techniques:

Monitoring:
Advise patients to contact their healthcare provider if they develop any signs and symptoms of infections.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.