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Medications for Crohn's Disease

About Crohn's Disease:  Crohn's disease is a chronic inflammatory disease of the intestines. It can affect any area of the gastrointestinal tract, though it mostly affects the small and large intestine.

Drugs Used to Treat Crohn's Disease

The following list of medications are in some way related to, or used in the treatment of this condition.

Drug name Rx / OTC Pregnancy CSA Alcohol Reviews Rating Popularity
Humira B N 33 reviews
5.0

Generic name: adalimumab systemic

Drug class: antirheumatics, TNF alfa inhibitors

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

Remicade B N 12 reviews
6.0

Generic name: infliximab systemic

Drug class: antirheumatics, TNF alfa inhibitors

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

mesalamine Off Label B N 28 reviews
7.0

Generic name: mesalamine systemic

Drug class: 5-aminosalicylates

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off Label: Yes

azathioprine D N 6 reviews
6.0

Generic name: azathioprine systemic

Brand names:  Imuran, Azasan

Drug class: antirheumatics, other immunosuppressants

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

budesonide C N 7 reviews
6.0

Generic name: budesonide systemic

Brand name:  Entocort EC

Drug class: inhaled corticosteroids, glucocorticoids

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Entocort EC C N 5 reviews
7.0

Generic name: budesonide systemic

Drug class: glucocorticoids

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Imuran D N 4 reviews
4.0

Generic name: azathioprine systemic

Drug class: antirheumatics, other immunosuppressants

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

hyoscyamine Off Label C N X 3 reviews
8.0

Generic name: hyoscyamine systemic

Drug class: anticholinergics/antispasmodics

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off Label: Yes

sulfasalazine Off Label B N 8 reviews
8.0

Generic name: sulfasalazine systemic

Drug class: antirheumatics, 5-aminosalicylates

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off Label: Yes

Cimzia B N 2 reviews
7.0

Generic name: certolizumab systemic

Drug class: TNF alfa inhibitors

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

adalimumab B N 33 reviews
5.0

Generic name: adalimumab systemic

Brand names:  Humira, Amjevita, Cyltezo

Drug class: antirheumatics, TNF alfa inhibitors

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph

infliximab B N 14 reviews
6.0

Generic name: infliximab systemic

Brand names:  Remicade, Inflectra, Ixifi, Renflexis …show all

Drug class: antirheumatics, TNF alfa inhibitors

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph

Entyvio B N 16 reviews
4.0

Generic name: vedolizumab systemic

Drug class: selective immunosuppressants

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph

cholestyramine Off Label C N 10 reviews
8.0

Generic name: cholestyramine systemic

Drug class: bile acid sequestrants

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off Label: Yes

vedolizumab B N 17 reviews
4.0

Generic name: vedolizumab systemic

Brand name:  Entyvio

Drug class: selective immunosuppressants

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Stelara B N 7 reviews
8.0

Generic name: ustekinumab systemic

Drug class: interleukin inhibitors

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

Azasan D N 1 review
10

Generic name: azathioprine systemic

Drug class: antirheumatics, other immunosuppressants

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

certolizumab B N 2 reviews
7.0

Generic name: certolizumab systemic

Brand name:  Cimzia

Drug class: TNF alfa inhibitors

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph

rifaximin Off Label C N 4 reviews
9.0

Generic name: rifaximin systemic

Drug class: miscellaneous antibiotics

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph

Off Label: Yes

cyclosporine Off Label C N Add review Rate

Generic name: cyclosporine systemic

Drug class: calcineurin inhibitors

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off Label: Yes

tacrolimus Off Label C N 3 reviews
6.0

Generic name: tacrolimus systemic

Drug class: calcineurin inhibitors

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off Label: Yes

ustekinumab B N 9 reviews
7.0

Generic name: ustekinumab systemic

Brand name:  Stelara

Drug class: interleukin inhibitors

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph

mycophenolate mofetil Off Label D N Add review Rate

Generic name: mycophenolate mofetil systemic

Drug class: selective immunosuppressants

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off Label: Yes

Amjevita B N Add review Rate

Generic name: adalimumab systemic

Drug class: antirheumatics, TNF alfa inhibitors

For consumers: dosage, interactions, side effects

Cyltezo B N Add review Rate

Generic name: adalimumab systemic

For consumers: dosage, interactions, side effects

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Topics under Crohn's Disease

Learn more about Crohn's Disease

Symptoms and treatments

Drugs.com Health Center

Mayo Clinic Reference

Legend

Off Label This medication may not be approved by the FDA for the treatment of this condition.
Prescription Only / Over the Counter
Rx Prescription Only
OTC Over the Counter
Rx/OTC Prescription or Over the Counter
Pregnancy
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act Schedule
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

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