Medications for Crohn's Disease

Crohn's disease is a chronic inflammatory disease of the intestines. It can affect any area of the gastrointestinal tract, though it mostly affects the small and large intestine.

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Drugs used to treat Crohn's Disease

The following list of medications are in some way related to or used in the treatment of this condition.

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Brands and Generics

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Rx and OTC

Drug name	Rating	Reviews	Rx/OTC	Pregnancy	CSA	Alcohol
Remicade	5.1	16 reviews	Rx	B	N
Generic name: infliximab systemic Drug class: antirheumatics, TNF alfa inhibitors For consumers: dosage, interactions, side effects For professionals: Prescribing Information

Humira	4.6	58 reviews	Rx	B	N
Generic name: adalimumab systemic Drug class: antirheumatics, TNF alfa inhibitors For consumers: dosage, interactions, side effects For professionals: Prescribing Information

mesalamine Off-label	7.1	32 reviews	Rx	B	N
Generic name: mesalamine systemic Drug class: 5-aminosalicylates For consumers: dosage, interactions, side effects For professionals: AHFS DI Monograph, Prescribing Information Off-label: Yes

Entyvio	6.1	49 reviews	Rx	B	N
Generic name: vedolizumab systemic Drug class: selective immunosuppressants For consumers: dosage, interactions, side effects For professionals: Prescribing Information

sulfasalazine Off-label	7.9	12 reviews	Rx	B	N
Generic name: sulfasalazine systemic Drug class: antirheumatics, 5-aminosalicylates For consumers: dosage, interactions, side effects For professionals: AHFS DI Monograph, Prescribing Information Off-label: Yes

azathioprine	5.5	13 reviews	Rx	D	N
Generic name: azathioprine systemic Brand names: Imuran, Azasan Drug class: antirheumatics, other immunosuppressants For consumers: dosage, interactions, side effects For professionals: AHFS DI Monograph, Prescribing Information

Cimzia	6.5	4 reviews	Rx	B	N
Generic name: certolizumab systemic Drug class: TNF alfa inhibitors For consumers: dosage, interactions, side effects For professionals: Prescribing Information

budesonide	6.3	17 reviews	Rx	C	N
Generic name: budesonide systemic Brand names: Entocort EC, Ortikos Drug class: inhaled corticosteroids, glucocorticoids For consumers: dosage, interactions, side effects For professionals: AHFS DI Monograph, Prescribing Information

Stelara	5.8	53 reviews	Rx	B	N
Generic name: ustekinumab systemic Drug class: interleukin inhibitors For consumers: dosage, interactions, side effects For professionals: Prescribing Information

vedolizumab	5.9	57 reviews	Rx	B	N
Generic name: vedolizumab systemic Brand name: Entyvio Drug class: selective immunosuppressants For consumers: dosage, interactions, side effects For professionals: AHFS DI Monograph

certolizumab	6.5	4 reviews	Rx	B	N
Generic name: certolizumab systemic Brand name: Cimzia Drug class: TNF alfa inhibitors For consumers: dosage, interactions, side effects For professionals: AHFS DI Monograph

Entocort EC	7.6	6 reviews	Rx	C	N
Generic name: budesonide systemic Drug class: glucocorticoids For consumers: dosage, interactions, side effects For professionals: Prescribing Information

Renflexis	Rate	Add review	Rx	B	N
Generic name: infliximab systemic Drug class: TNF alfa inhibitors For consumers: dosage, interactions, side effects For professionals: Prescribing Information

Avsola	Rate	Add review	Rx	B	N
Generic name: infliximab systemic Drug class: TNF alfa inhibitors For consumers: dosage, interactions, side effects For professionals: Prescribing Information

hyoscyamine Off-label	9.3	4 reviews	Rx	C	N	X
Generic name: hyoscyamine systemic Drug class: anticholinergics/antispasmodics For consumers: dosage, interactions, side effects For professionals: AHFS DI Monograph, Prescribing Information Off-label: Yes

Imuran	3.3	6 reviews	Rx	D	N
Generic name: azathioprine systemic Drug class: antirheumatics, other immunosuppressants For consumers: dosage, interactions, side effects For professionals: Prescribing Information

risankizumab	6.0	2 reviews	Rx		N
Generic name: risankizumab systemic Brand name: Skyrizi Drug class: interleukin inhibitors For consumers: dosage, interactions, side effects For professionals: AHFS DI Monograph

Skyrizi	8.0	1 review	Rx		N
Generic name: risankizumab systemic Drug class: interleukin inhibitors For consumers: dosage, interactions, side effects For professionals: Prescribing Information

cholestyramine Off-label	9.3	17 reviews	Rx	C	N
Generic name: cholestyramine systemic Drug class: bile acid sequestrants For consumers: dosage, interactions, side effects For professionals: AHFS DI Monograph Off-label: Yes

infliximab	4.1	28 reviews	Rx	B	N
Generic name: infliximab systemic Brand names: Remicade, Renflexis, Avsola, Inflectra, Ixifi …show all Drug class: antirheumatics, TNF alfa inhibitors For consumers: dosage, interactions, side effects For professionals: AHFS DI Monograph, Prescribing Information

adalimumab	4.5	59 reviews	Rx	B	N
Generic name: adalimumab systemic Brand names: Humira, Amjevita, Cyltezo, Abrilada, Hadlima, Hulio, Hyrimoz, Yusimry, Idacio …show all Drug class: antirheumatics, TNF alfa inhibitors For consumers: dosage, interactions, side effects For professionals: AHFS DI Monograph

Azasan	10	1 review	Rx	D	N
Generic name: azathioprine systemic Drug class: antirheumatics, other immunosuppressants For consumers: dosage, interactions, side effects For professionals: Prescribing Information

rifaximin Off-label	9.3	7 reviews	Rx	C	N
Generic name: rifaximin systemic Drug class: miscellaneous antibiotics For consumers: dosage, interactions, side effects For professionals: AHFS DI Monograph Off-label: Yes

Ortikos	Rate	Add review	Rx	C	N
Generic name: budesonide systemic Drug class: glucocorticoids For consumers: dosage, interactions, side effects For professionals: Prescribing Information

tacrolimus Off-label	8.5	3 reviews	Rx	C	N
Generic name: tacrolimus systemic Drug class: calcineurin inhibitors For consumers: dosage, interactions, side effects For professionals: AHFS DI Monograph, Prescribing Information Off-label: Yes

Frequently asked questions

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Topics under Crohn's Disease

Crohn's Disease, Acute (45 drugs)
Crohn's Disease, Maintenance (35 drugs)

Learn more about Crohn's Disease

Crohn's Disease Health Article

Legend

Rating	For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).
Activity	Activity is based on recent site visitor activity relative to other medications in the list.
Rx	Prescription only.
OTC	Over-the-counter.
Rx/OTC	Prescription or Over-the-counter.
Off-label	This medication may not be approved by the FDA for the treatment of this condition.
EUA	An Emergency Use Authorization (EUA) allows the FDA to authorize unapproved medical products or unapproved uses of approved medical products to be used in a declared public health emergency when there are no adequate, approved, and available alternatives.
Expanded Access	Expanded Access is a potential pathway for a patient with a serious or immediately life-threatening disease or condition to gain access to an investigational medical product (drug, biologic, or medical device) for treatment outside of clinical trials when no comparable or satisfactory alternative therapy options are available.

Pregnancy Category
A	Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B	Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C	Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D	There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X	Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N	FDA has not classified the drug.

Controlled Substances Act (CSA) Schedule
M	The drug has multiple schedules. The schedule may depend on the exact dosage form or strength of the medication.
U	CSA Schedule is unknown.
N	Is not subject to the Controlled Substances Act.
1	Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2	Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3	Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4	Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5	Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.

Alcohol
X	Interacts with Alcohol.

Further information

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