Hyoscyamine Side Effects
For the Consumer
Applies to hyoscyamine: oral conventional tablets and sublingual tablets, oral extended-release capsules and tablets, oral oral solution and elixir, oral orally disintegrating tablets, parenteral injection
Side effects include:
Most adverse effects are manifestations of pharmacologic effects at muscarinic-cholinergic receptors and usually are reversible when therapy is discontinued.
Severity and frequency of adverse effects are dose related and individual intolerance varies greatly; adverse effects occasionally may be obviated by a reduction in dosage but this also may eliminate potential therapeutic effects.
Adverse effects include dry mouth, urinary hesitancy and retention, blurred vision, tachycardia, palpitations, mydriasis, increased ocular tension, loss of taste, headache, nervousness, drowsiness, weakness, fatigue, dizziness, insomnia, nausea, vomiting, impotence, constipation, bloated feeling, abdominal pain, diarrhea, allergic reactions or drug idiosyncrasies, urticaria and other dermal manifestations, ataxia, speech disturbance, mental confusion and/or excitement (especially in geriatric patients), short-term memory loss, hallucinations, and decreased sweating.
For Healthcare Professionals
Applies to hyoscyamine: compounding powder, injectable solution, oral capsule extended release, oral liquid, oral solution, oral spray, oral tablet, oral tablet chewable, oral tablet disintegrating, oral tablet extended release, sublingual tablet
Frequency not reported: Tachycardia, palpitations[Ref]
Frequency not reported: Dryness of the mouth, nausea, vomiting, constipation, bloated feeling, abdominal pain, diarrhea[Ref]
Frequency not reported: Urinary hesitancy and retention, impotence[Ref]
Frequency not reported: Allergic reactions or drug idiosyncrasies[Ref]
Frequency not reported: Loss of taste, headache, drowsiness, dizziness, ataxia, speech disturbance, some degree of mental confusion and/or excitement (especially in elderly persons), short-term memory loss[Ref]
Frequency not reported: Blurred vision, mydriasis, increased ocular tension[Ref]
Frequency not reported: Nervousness, insomnia, hallucinations[Ref]
Frequency not reported: Weakness, fatigue[Ref]
Frequency not reported: Urticaria and other dermal manifestations, decreased sweating[Ref]
1. "Product Information. Symax SR (hyoscyamine)." Capellon Pharmaceuticals, Fort Worth, TX.
Some side effects may not be reported. You may report them to the FDA.
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