Hyoscyamine Alternatives Compared

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Hyoscyamine	Botox (onabotulinumtoxinA)	Oxybutynin	Enter another drug to compare

Hyoscyamine

Botox (onabotulinumtoxinA)

Oxybutynin

Prescription only

Hyoscyamine may be used in the treatment of a wide variety of gastrointestinal problems including cramps, bladder control issues, and irritable bowel syndrome. Drowsiness and dry mouth are common... View more

Prescription only

Botox is approved to treat many conditions, such as chronic migraine, involuntary muscle contractions or twitching, excessive sweating, increased saliva, and overactive bladder to name a few. Botox... View more

Prescription and OTC

Oxybutynin helps to relieve symptoms of an overactive bladder and urinary incontinence but it may cause side effects such as a dry mouth and constipation. Prescribed for Overactive Bladder... View more

More about Hyoscyamine

More about Botox (onabotulinumtoxinA)

More about Oxybutynin

Ratings & Reviews

Hyoscyamine has an average rating of 7.8 out of 10 from a total of 116 ratings on Drugs.com. 72% of reviewers reported a positive effect, while 16% reported a negative effect.

Botox has an average rating of 5.7 out of 10 from a total of 473 ratings on Drugs.com. 47% of reviewers reported a positive effect, while 41% reported a negative effect.

Oxybutynin has an average rating of 6.7 out of 10 from a total of 459 ratings on Drugs.com. 53% of reviewers reported a positive effect, while 24% reported a negative effect.

View all 116 reviews

View all 473 reviews

View all 459 reviews

Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified.

Dry mouth (17.2%)
Constipation (6.9%)
Drowsiness (6.9%)
Cramps (4.3%)
Diarrhea (4.3%)
Dry eyes (3.4%)
Bloating (2.6%)

View all Hyoscyamine side effects

Pain (18.0%)
Headaches (8.2%)
Neck pain (5.9%)
Urinary tract infection (4.9%)
Anxiety (3.6%)
Migraine (3.6%)
Dizziness (3.4%)

View all Botox side effects

Dry mouth (32.0%)
Constipation (4.8%)
Dizziness (4.8%)
Sweating (4.6%)
Drowsiness (4.1%)
Itching (3.9%)
Nausea (3.7%)

View all Oxybutynin side effects

Drug Class

Anticholinergics/antispasmodics

Skeletal muscle relaxants

Urinary antispasmodics

Generic Availability

Lower cost generic

N/A

Lower cost generic

Pricing and Coupons * Prices are without insurance

Quantity	100 tablet
Strength	0.125 mg
Per unit^*	$0.39
Cost^*	$38.90

View all Hyoscyamine prices

Quantity	1 powder for injection
Strength	100 units
Per unit^*	$699.62
Cost^*	$699.62

View all Botox prices

Quantity	100 each
Strength	5 mg
Per unit^*	$0.32
Cost^*	$32.05

View all Oxybutynin prices

Get free Discount Card

Dosage Forms

Injectable solution
Oral liquid
Oral solution
Oral tablet
Oral tablet, disintegrating
Oral tablet, extended release
Sublingual tablet

Injectable powder for injection

Oral solution
Oral syrup
Oral tablet
Oral tablet, extended release

Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value.

4 hours

N/A

2.3 hours

CSA Schedule ¹ View glossary of CSA terms

Not a controlled drug

Is not subject to the Controlled Substances Act.

Not a controlled drug

Is not subject to the Controlled Substances Act.

Not a controlled drug

Is not subject to the Controlled Substances Act.

Pregnancy Category

Category C Risk cannot be ruled out

See the full pregnancy warnings document.

Category C Risk cannot be ruled out

See the full pregnancy warnings document.

Category B No proven risk in humans

See the full pregnancy warnings document.

Drug Interactions

A total of 208 drugs are known to interact with Hyoscyamine:

6 major drug interactions (67 brand and generic names)
185 moderate drug interactions (907 brand and generic names)
17 minor drug interactions (400 brand and generic names)

A total of 120 drugs are known to interact with Botox:

25 major drug interactions (60 brand and generic names)
95 moderate drug interactions (557 brand and generic names)

A total of 286 drugs are known to interact with Oxybutynin:

5 major drug interactions (65 brand and generic names)
261 moderate drug interactions (1106 brand and generic names)
20 minor drug interactions (403 brand and generic names)

Alcohol/Food/Lifestyle Interactions

Ask your doctor before using hyoscyamine together with alcohol. Use alcohol cautiously. Alcohol... View more

No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider.

Ask your doctor before using oxyBUTYnin together with alcohol. Use alcohol cautiously. Alcohol... View more

Disease Interactions

First Approval Date

N/A

December 09, 1991

July 16, 1975

WADA Class View classifications

N/A

More Information

Patient Resources

Hyoscyamine uses

Botox uses

Oxybutynin uses

Professional Resources

Prescribing information

¹ The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

Hyoscyamine Alternatives Compared

Further information

Compare Drugs