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Medications for Hyperhidrosis

Other names: Excessive Perspiration; Sweating

What is Hyperhidrosis:  Excessive perspiration. Also called hyperidrosis, polyhidrosis and polyidrosis.

Medications to treat Hyperhidrosis

The following list of medications are in some way related to, or used in the treatment of this condition.

Drug name Rx / OTC Pregnancy CSA Alcohol Reviews Rating Popularity
Drysol C N 224 reviews
9.0

Generic name: aluminum chloride hexahydrate topical

Drug class: miscellaneous topical agents

For consumers: side effects

 
oxybutynin Off Label B N X 50 reviews
8.0

Generic name: oxybutynin systemic

Drug class: urinary antispasmodics

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off Label: Yes

 
Hypercare C N 209 reviews
8.0

Generic name: aluminum chloride hexahydrate topical

Drug class: miscellaneous topical agents

For consumers: dosage, side effects

For professionals: Prescribing Information

 
Hytrin Off Label C N X 1 review
9.0

Generic name: terazosin systemic

Drug class: antiadrenergic agents, peripherally acting

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Off Label: Yes

 
clonidine Off Label C N X 4 reviews
7.0

Generic name: clonidine systemic

Drug class: antiadrenergic agents, centrally acting

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off Label: Yes

 
terazosin Off Label C N X 3 reviews
8.0

Generic name: terazosin systemic

Brand name:  Hytrin

Drug class: antiadrenergic agents, peripherally acting

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off Label: Yes

 
benztropine Off Label N N X Add review Rate

Generic name: benztropine systemic

Drug class: anticholinergic antiparkinson agents

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off Label: Yes

 
gabapentin Off Label C N X Add review Rate

Generic name: gabapentin systemic

Drug class: gamma-aminobutyric acid analogs

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off Label: Yes

 
aluminum chloride hexahydrate C N 456 reviews
9.0

Generic name: aluminum chloride hexahydrate topical

Brand names:  Drysol, Hypercare, Xerac AC, B+Drier

Drug class: miscellaneous topical agents

For consumers: side effects

For professionals: AHFS DI Monograph, Prescribing Information

 
Xerac AC C N 9 reviews
9.0

Generic name: aluminum chloride hexahydrate topical

Drug class: miscellaneous topical agents

For consumers: side effects

 
amitriptyline Off Label C N X 2 reviews
5.0

Generic name: amitriptyline systemic

Drug class: tricyclic antidepressants

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off Label: Yes

 
Botox C N 2 reviews
6.0

Generic name: onabotulinumtoxinA systemic

Drug class: skeletal muscle relaxants

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

 
Myobloc C N Add review Rate

Generic name: botulinum toxin type b systemic

Drug class: skeletal muscle relaxants

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

 
botulinum toxin type b C N Add review Rate

Generic name: botulinum toxin type b systemic

Brand name:  Myobloc

Drug class: skeletal muscle relaxants

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph

 
onabotulinumtoxinA C N 2 reviews
6.0

Generic name: onabotulinumtoxinA systemic

Brand name:  Botox

Drug class: skeletal muscle relaxants

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph

 
B+Drier C N Add review Rate

Generic name: aluminum chloride hexahydrate topical

Drug class: miscellaneous topical agents

For consumers: side effects

 

Learn more about Hyperhidrosis

Legend

Off Label This medication may not be approved by the FDA for the treatment of this condition.
Prescription Only / Over the Counter
Rx Prescription Only
OTC Over the Counter
Rx/OTC Prescription or Over the Counter
Pregnancy
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act Schedule
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

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