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What is botulinum toxin used to treat?

Medically reviewed by Judith Stewart, BPharm. Last updated on Feb 16, 2021.

What is botulinum toxin? What are the uses of the FDA approved botulinum toxin products?

Official Answer

by Drugs.com

Botulinum toxin is used in the treatment of overactive bladder, urinary incontinence, chronic migraines, spasticity (contractions causing muscle stiffness), cervical dystonia (neck muscles contracting involuntarily), severe underarm sweating, eyelid spasms, crossed eyes, and drooling. It is also used for the treatment of facial lines and wrinkles.

What is botulinum toxin?
Botulinum toxin is a neurotoxin produced by Clostridium botulinum, the bacteria that causes botulism. The botulinum toxin was found to cause muscle paralysis in the body, and over time this led to the discovery and development of the pharmaceutical products we have available today.

What are the uses of the FDA approved botulinum toxin products?

Botox (onabotulinumtoxinA) for injection

  • overactive bladder
  • urinary incontinence
  • pediatric neurogenic detrusor overactivity
  • chronic migraine
  • spasticity
  • cervical dystonia
  • severe axillary hyperhidrosis (underarm sweating)
  • blepharospasm (spasm of the eyelids)
  • strabismus (crossed eyes)

Botox Cosmetic (onabotulinumtoxinA) for injection

  • glabellar lines (frown lines)
  • lateral canthal lines ("crow's feet")
  • forehead lines

Myobloc (rimabotulinumtoxinB) Injection

  • cervical dystonia
  • chronic sialorrhea (drooling)

Dysport (abobotulinumtoxinA) for Injection

  • cervical dystonia
  • glabellar lines (frown lines)
  • spasticity

Xeomin (incobotulinumtoxinA) for Injection

  • excessive salivation
  • upper limb spasticity
  • cervical dystonia
  • blepharospasm
  • glabellar lines (frown lines)

Jeuveau (prabotulinumtoxinA-xvfs) for Injection

  • glabellar lines (frown lines)

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