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Benztropine Side Effects

Medically reviewed by Drugs.com. Last updated on Dec 2, 2023.

Applies to benztropine: oral tablet.

Other dosage forms:

Precautions

It is important that your doctor check your progress at regular visits to allow changes in your dose and to check for any unwanted effects.

Benztropine may cause dizziness, trouble in controlling movements, or trouble in thinking or seeing clearly. Make sure you know how you react to this medicine before you drive, use machines, or do other jobs that require you to be alert, well-coordinated, or able to think or see well.

Do not Stop taking benztropine without first checking with your doctor. Your doctor may want you to gradually reduce the amount you are using before stopping completely.

This medicine may make you sweat less, causing your body temperature to increase. Use extra care to avoid becoming overheated during exercise or hot weather while you are taking this medicine, since overheating may result in heat stroke.

This medicine may cause muscle weakness. If you have concerns about this, check with your doctor.

If you develop any unusual or strange thoughts and behavior while receiving benztropine, be sure to discuss it with your doctor. Some changes that have occurred in people receiving this medicine are like those seen in people who drink too much alcohol. Other changes might be confusion, worsening of depression, visual hallucinations (seeing things that are not there), suicidal thoughts, and unusual excitement, nervousness, or irritability.

This medicine will add to the effects of alcohol and other CNS depressants (medicines that make you drowsy or less alert). Some examples of CNS depressants are antihistamines or medicine for hay fever, other allergies, or colds; sedatives, tranquilizers, or sleeping medicine; prescription pain medicine or narcotics; barbiturates; medicine for seizures; muscle relaxants; or anesthetics, including some dental anesthetics. Check with your medical doctor or dentist before taking any of the above while you are taking this medicine.

Serious side effects of benztropine

Along with its needed effects, benztropine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking benztropine:

Incidence not known

  • abdominal or stomach cramps or pain
  • aggressive and violent behavior
  • being forgetful
  • bloating
  • burning while urinating
  • confusion about identity, place, and time
  • constipation
  • decrease in frequency of urination
  • decrease in urine volume
  • diarrhea
  • difficult or painful urination
  • difficulty in passing urine (dribbling)
  • difficulty with speaking
  • difficulty with swallowing
  • discouragement
  • dizziness
  • dry mouth
  • extremely high fever or body temperature
  • fast, pounding, or irregular heartbeat or pulse
  • fast, shallow breathing
  • fast, weak heartbeat
  • feeling sad or empty
  • fever
  • headache
  • hot, dry skin
  • irritability
  • lack of appetite
  • lack of sweating
  • listlessness
  • loss of interest or pleasure
  • mood or mental changes
  • muscle cramps
  • muscle weakness
  • nervousness
  • numbness of the fingers
  • pale, clammy skin
  • seeing things that are not there
  • thirst
  • tiredness
  • trouble concentrating
  • trouble with sleeping
  • vomiting

Get emergency help immediately if any of the following symptoms of overdose occur while taking benztropine:

Symptoms of overdose

Other side effects of benztropine

Some side effects of benztropine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Incidence not known

  • enlarged pupils
  • loss of appetite
  • skin rash
  • weight loss

For healthcare professionals

Applies to benztropine: compounding powder, injectable solution, oral tablet.

General adverse events

Adverse reactions are anticholinergic in nature and include dry mouth, constipation, tachycardia, and blurred vision.[Ref]

Nervous system

Psychiatric

Gastrointestinal

Ocular

Cardiovascular

Genitourinary

Hypersensitivity

Other

Dermatologic

See also:

References

1. (2001) "Product Information. Cogentin (benztropine)." Merck & Co., Inc

2. Cerner Multum, Inc. "Australian Product Information."

Further information

Benztropine side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.