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Medications for Parkinson's Disease

A progressive, neurological disease first described in 1817 by James Parkinson. The pathology is not completely understood, but there appears to be consistent changes in the melanin-containing nerve cells in the brainstem. Common medications used to treat parkinson's disease include amantadine and Rytary.

Drugs used to treat Parkinson's Disease

The following list of medications are in some way related to, or used in the treatment of this condition.

Drug name Rating Reviews Activity ? Rx/OTC Pregnancy CSA Alcohol
carbidopa / levodopa 6.4 46 reviews
Rx C N X

Generic name: carbidopa / levodopa systemic

Brand names:  Sinemet, Sinemet CR, Rytary, Duopa, Parcopa, Dhivy …show all

Drug class: dopaminergic antiparkinsonism agents

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

Sinemet 7.6 10 reviews
Rx C N X

Generic name: carbidopa / levodopa systemic

Drug class: dopaminergic antiparkinsonism agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Azilect 7.4 10 reviews
Rx C N X

Generic name: rasagiline systemic

Drug class: dopaminergic antiparkinsonism agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

amantadine 7.1 15 reviews
Rx C N

Generic name: amantadine systemic

Brand names:  Gocovri, Osmolex ER

Drug class: adamantane antivirals, dopaminergic antiparkinsonism agents

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

Sinemet CR 7.5 2 reviews
Rx C N X

Generic name: carbidopa / levodopa systemic

Drug class: dopaminergic antiparkinsonism agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Rytary 5.5 24 reviews
Rx C N X

Generic name: carbidopa / levodopa systemic

Drug class: dopaminergic antiparkinsonism agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

rasagiline 6.5 14 reviews
Rx C N X

Generic name: rasagiline systemic

Brand name:  Azilect

Drug class: dopaminergic antiparkinsonism agents

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

Neupro 6.6 20 reviews
Rx C N X

Generic name: rotigotine systemic

Drug class: dopaminergic antiparkinsonism agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

levodopa Rate Add review
Rx N N X

Generic name: levodopa systemic

Brand name:  Inbrija

Drug class: dopaminergic antiparkinsonism agents

For consumers: dosage, interactions, side effects

Duopa Rate Add review
Rx C N X

Generic name: carbidopa / levodopa systemic

Drug class: dopaminergic antiparkinsonism agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Apokyn 7.3 3 reviews
Rx C N X

Generic name: apomorphine systemic

Drug class: dopaminergic antiparkinsonism agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Gocovri Rate Add review
Rx C N

Generic name: amantadine systemic

Drug class: dopaminergic antiparkinsonism agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

rotigotine 6.6 20 reviews
Rx C N X

Generic name: rotigotine systemic

Brand name:  Neupro

Drug class: dopaminergic antiparkinsonism agents

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph

apomorphine 7.5 4 reviews
Rx C N X

Generic name: apomorphine systemic

Brand names:  Apokyn, Kynmobi

Drug class: dopaminergic antiparkinsonism agents

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph

Inbrija Rate Add review
Rx N N X

Generic name: levodopa systemic

Drug class: dopaminergic antiparkinsonism agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Xadago 10 2 reviews
Rx N X

Generic name: safinamide systemic

Drug class: dopaminergic antiparkinsonism agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Kynmobi Rate Add review
Rx C N X

Generic name: apomorphine systemic

Drug class: dopaminergic antiparkinsonism agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

safinamide 10 2 reviews
Rx N X

Generic name: safinamide systemic

Brand name:  Xadago

Drug class: dopaminergic antiparkinsonism agents

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph

Nourianz 8.0 1 review
Rx N

Generic name: istradefylline systemic

Drug class: miscellaneous antiparkinson agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Ongentys Rate Add review
Rx N X

Generic name: opicapone systemic

Drug class: dopaminergic antiparkinsonism agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

ropinirole 5.2 14 reviews
Rx C N X

Generic name: ropinirole systemic

Brand names:  Requip, Requip XL

Drug class: dopaminergic antiparkinsonism agents

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

pramipexole 4.7 15 reviews
Rx C N X

Generic name: pramipexole systemic

Brand names:  Mirapex, Mirapex ER

Drug class: dopaminergic antiparkinsonism agents

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

Mirapex 4.7 7 reviews
Rx C N X

Generic name: pramipexole systemic

Drug class: dopaminergic antiparkinsonism agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Requip 2.2 6 reviews
Rx C N X

Generic name: ropinirole systemic

Drug class: dopaminergic antiparkinsonism agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

selegiline 9.7 3 reviews
Rx C N X

Generic name: selegiline systemic

Brand names:  Eldepryl, Zelapar

Drug class: monoamine oxidase inhibitors, dopaminergic antiparkinsonism agents

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

Topics under Parkinson's Disease

Alternative treatments for Parkinson's Disease

The following products are considered to be alternative treatments or natural remedies for Parkinson's Disease. Their efficacy may not have been scientifically tested to the same degree as the drugs listed in the table above. However there may be historical, cultural or anecdotal evidence linking their use to the treatment of Parkinson's Disease.

Learn more about Parkinson's Disease

IBM Watson Micromedex

Symptoms and treatments

Drugs.com Health Center

Mayo Clinic Reference

Legend

Rating For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).
Activity Activity is based on recent site visitor activity relative to other medications in the list.
Rx Prescription only.
OTC Over-the-counter.
Rx/OTC Prescription or Over-the-counter.
Off-label This medication may not be approved by the FDA for the treatment of this condition.
EUA An Emergency Use Authorization (EUA) allows the FDA to authorize unapproved medical products or unapproved uses of approved medical products to be used in a declared public health emergency when there are no adequate, approved, and available alternatives.
Pregnancy Category
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act (CSA) Schedule
M The drug has multiple schedules. The schedule may depend on the exact dosage form or strength of the medication.
U CSA Schedule is unknown.
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

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Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.