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Medications for Parkinson's Disease

Drugs associated with Parkinson's Disease

The following drugs and medications are in some way related to, or used in the treatment of this condition.

What is Parkinson's Disease: A progressive, neurological disease first described in 1817 by James Parkinson.

The pathology is not completely understood, but there appears to be consistent changes in the melanin-containing nerve cells in the brainstem

Drug name Rx / OTC Pregnancy CSA Alcohol Reviews Rating Popularity
Sinemet Rx C N X 4 reviews
9.0

Generic name: carbidopa / levodopa systemic

Drug class: dopaminergic antiparkinsonism agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
carbidopa / levodopa Rx C N X 12 reviews
7.0

Generic name: carbidopa / levodopa systemic

Brand names:  Sinemet, Sinemet CR, Parcopa, Rytary, Duopa

Drug class: dopaminergic antiparkinsonism agents

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
Azilect Rx C N 6 reviews
7.0

Generic name: rasagiline systemic

Drug class: dopaminergic antiparkinsonism agents

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

 
Mirapex Rx C N X 4 reviews
5.0

Generic name: pramipexole systemic

Drug class: dopaminergic antiparkinsonism agents

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

 
Requip Rx C N X 4 reviews
4.0

Generic name: ropinirole systemic

Drug class: dopaminergic antiparkinsonism agents

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

 
Sinemet CR Rx C N X 2 reviews
7.0

Generic name: carbidopa / levodopa systemic

Drug class: dopaminergic antiparkinsonism agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
amantadine Rx C N 8 reviews
7.0

Generic name: amantadine systemic

Drug class: adamantane antivirals, dopaminergic antiparkinsonism agents

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
ropinirole Rx C N X 9 reviews
5.0

Generic name: ropinirole systemic

Brand names:  Requip, Requip XL

Drug class: dopaminergic antiparkinsonism agents

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
Comtan Rx C N X 3 reviews
5.0

Generic name: entacapone systemic

Drug class: dopaminergic antiparkinsonism agents

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

 
pramipexole Rx C N X 6 reviews
5.0

Generic name: pramipexole systemic

Brand names:  Mirapex, Mirapex ER

Drug class: dopaminergic antiparkinsonism agents

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
Requip XL Rx C N X 4 reviews
7.0

Generic name: ropinirole systemic

Drug class: dopaminergic antiparkinsonism agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
Cogentin Rx N N X Add review Add

Generic name: benztropine systemic

Drug class: anticholinergic antiparkinson agents

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

 
Eldepryl Rx C N 1 review
10

Generic name: selegiline systemic

Drug class: monoamine oxidase inhibitors, dopaminergic antiparkinsonism agents

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

 
Mirapex ER Rx C N X 1 review
9.0

Generic name: pramipexole systemic

Drug class: dopaminergic antiparkinsonism agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
selegiline Rx C N 3 reviews
9.0

Generic name: selegiline systemic

Brand names:  Eldepryl, Zelapar

Drug class: monoamine oxidase inhibitors, dopaminergic antiparkinsonism agents

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
Neupro Rx C N X 9 reviews
7.0

Generic name: rotigotine systemic

Drug class: dopaminergic antiparkinsonism agents

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

 
Stalevo Rx C N X 5 reviews
6.0

Generic name: carbidopa / entacapone / levodopa systemic

Drug class: dopaminergic antiparkinsonism agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
Akineton Rx C N X Add review Add

Generic name: biperiden systemic

Drug class: anticholinergic antiparkinson agents

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

 
Artane Rx N N X 2 reviews
3.0

Generic name: trihexyphenidyl systemic

Drug class: anticholinergic antiparkinson agents

For consumers: dosage, interactions, side effects

 
Exelon Rx B N 2 reviews
4.0

Generic name: rivastigmine systemic

Drug class: cholinesterase inhibitors

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

 
Apokyn Rx C N X 3 reviews
7.0

Generic name: apomorphine systemic

Drug class: dopaminergic antiparkinsonism agents

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

 
trihexyphenidyl Rx N N X 4 reviews
3.0

Generic name: trihexyphenidyl systemic

Brand names:  Artane, Trihexane

Drug class: anticholinergic antiparkinson agents

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
benztropine Rx N N X Add review
9.0

Generic name: benztropine systemic

Brand name:  Cogentin

Drug class: anticholinergic antiparkinson agents

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
carbidopa / entacapone / levodopa Rx C N X 6 reviews
6.0

Generic name: carbidopa / entacapone / levodopa systemic

Brand names:  Stalevo, Stalevo 100, Stalevo 150, Stalevo 200, Stalevo 50, Stalevo 75, Stalevo 125

Drug class: dopaminergic antiparkinsonism agents

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, Prescribing Information

 
Parcopa Rx C N X Add review Add

Generic name: carbidopa / levodopa systemic

Drug class: dopaminergic antiparkinsonism agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
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Topics under Parkinson's Disease

Alternative treatments for Parkinson's Disease

The following products are considered to be alternative treatments or natural remedies for Parkinson's Disease. Their efficacy may not have been scientifically tested to the same degree as the drugs listed in the table above. However there may be historical, cultural or anecdotal evidence linking their use to the treatment of Parkinson's Disease.

Learn more about Parkinson's Disease

Legend

Off Label This medication may not be approved by the FDA for the treatment of this condition.
Prescription Only / Over the Counter
Rx Prescription Only
OTC Over the Counter
Rx/OTC Prescription or Over the Counter
Pregnancy
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use of the drug in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act Schedule
N The drug is not subject to the Controlled Substances Act.
1 The drug has a high potential for abuse. The drug has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use of the drug under medical supervision.
2 The drug has a high potential for abuse. The drug has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse of the drug may lead to severe psychological or physical dependence.
3 The drug has a potential for abuse less than the drugs in schedules 1 and 2. The drug has a currently accepted medical use in treatment in the United States. Abuse of the drug may lead to moderate or low physical dependence or high psychological dependence.
4 The drug has a low potential for abuse relative to the drugs in schedule 3. The drug has a currently accepted medical use in treatment in the United States. Abuse of the drug may lead to limited physical dependence or psychological dependence relative to the drugs in schedule 3.
5 The drug has a low potential for abuse relative to the drugs in schedule 4. The drug has a currently accepted medical use in treatment in the United States. Abuse of the drug may lead to limited physical dependence or psychological dependence relative to the drugs in schedule 4.
Alcohol
X Interacts with Alcohol.

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