Skip to Content

Monoamine oxidase inhibitors

A drug may be classified by the chemical type of the active ingredient or by the way it is used to treat a particular condition. Each drug can be classified into one or more drug classes.

Monoamine oxidase inhibitors (MAO inhibitors) inhibit one or both forms of the enzyme monoamine oxidase and prevent the breakdown of monoamine oxidase neurotransmitters.

The substrate for MAO-A enzyme is serotonin, melatonin, epinephrine and norepinephrine and for MAO-B is phenylethylene. Dopamine is a substrate for both the isoforms A and B.

Inhibition of Type A monoamine oxidase exerts a reversible or irreversible antidepressant effect. Inhibition of both Type A and B monoamine oxidase treats depression and anxiety.

The use of monoamine oxidase inhibitors is restricted now due to the severity of their interactions with other drugs and their adverse effects.

Filter by:
Drug Name DownUp( View by: Brand | Generic ) Reviews Ratings DownUp
Zelapar (Pro, More...)
generic name: selegiline
2 reviews
Marplan (Pro, More...)
generic name: isocarboxazid
2 reviews
Parnate (Pro, More...)
generic name: tranylcypromine
38 reviews
Eldepryl (Pro, More...)
generic name: selegiline
1 review
Emsam (Pro, More...)
generic name: selegiline
26 reviews
Nardil (Pro, More...)
generic name: phenelzine
30 reviews

See also...

Medical conditions associated with monoamine oxidase inhibitors: