User Reviews for Phenelzine
Also known as: Nardil
The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care.
Learn more about Phenelzine.
|Depression||37 reviews||79 medications|
|Migraine Prevention||2 reviews||29 medications|
|Summary of Phenelzine reviews||39 reviews||7.6|
Reviews for Phenelzine
Nardil (phenelzine) for Depression: "I took nardil for 4 years. It changed my personality drastically. I went from depressed and withdrawn to hypomanic (which is like half way to fully manic). Much more sociable and I also became a workaholic. The side effects were intolerable - extreme weight gain (gained 50 lbs which brought me over 200 lbs. had never been overweight before or since) and anorgasmia. I did prefer hypomania to unipolar depression but eventually I pooped out on it as everyone seems to do in these designer ADs within a few years. There was a study which found that MAOIs like Nardil can permanently damage your mu receptors preventing you from having the capability to experience euphoria and that happened to me also. I wish I never taken any of those drugs."
xzardozx (taken for 2 to 5 years) July 29, 2017
0 users found this comment helpful.
Nardil (phenelzine) for Depression: "I tried many medications and many combinations with little or no effect. As a last effort, I turned to the internet and stumbled across some positive info about Nardil. It took awhile to even find a doctor that would prescribe it. I have now been on 90 mgs for around four or five years and it works very well with few unwanted side effects. I take it in combination with 20mgs of Zyprexa for a very severe form of generalized anxiety that I have."
Anonymous (taken for 5 to 10 years) June 6, 2017
19 users found this comment helpful.
Nardil (phenelzine) for Depression: "Nardil is an amazing drug. I honestly do not know where I would be without it. I wish more doctors would be willing to prescribe it to people."
Cosis (taken for 10 years or more) April 9, 2017
16 users found this comment helpful.
Nardil (phenelzine) for Depression: "5 weeks after I started Nardil my life completely changed. After 15 years I could smile again. I have tried every drug under the sun for my depression and social anxiety (SSRIs, SNRIs, TCAs, APs, benzos, opiates) but nothing has worked until Nardil."
zeusovich (taken for 1 to 2 years) February 5, 2017
41 users found this comment helpful.
Nardil (phenelzine) for Depression: "Severe anxiety and debilitating depression - a normal active happy person reduced to nothing but the dark in a bed for months. Prescribed every drug in the book in every combination - twice! All absolutely utterly totally useless. One day my doc said we are going to try an unusual dangerous drug - Nardil, because its your only hope. FANTASTIC UTTERLY INCREDIBLE. In two days I was living again and I was nearly better."
Rick Pointar (taken for 6 months to 1 year) December 17, 2016
41 users found this comment helpful.
Nardil (phenelzine) for Depression: "I am currently taking 15 mg three x per day (total of 45mg). The first month was the worst. The main side effect that I had was body aches and muscle stiffness that never lessened. Once a month passed the body aches went away and I noticed a faint constant headache. After about a week that went away too. The only side effect I notice now (after 2 months on Nardil) is a pounding headache lasting 10 seconds and light headedness when I get up to stand from laying down and swelling. It give it 4/10 because it has made my suicidal thoughts disappear and I am less teary and emotional. Has not helped my overall mood or general sense of wellbeing. I find the dietary restrictions hard to follow."
Chinooker (taken for 1 to 6 months) November 26, 2016
8 users found this comment helpful.
Nardil (phenelzine) for Depression: "Works very well for my depression. Only medication I found that actually works.. I have tried a bunch too. From SSRI to SNRI to benzo . I am on 90mg and im about to reach 1 month on Nardil. I hope it only gets better! I really recommend this medication if all the others failed. Love you Nardil!!!"
Farshad1997 (taken for less than 1 month) November 12, 2016
12 users found this comment helpful.
Nardil (phenelzine) for Depression: "I've struggled with depression and social anxiety all my life and have recently been treated with a variety of different antidepressants. I think I am depressed because of a narsisstic mother who seemed to be unable to love unconditionally. While Nardil might well help others, I don't feel it has helped me and the effect on sexual activity it depressing in itself. I am currently seeing a psychotherapist and while it is very hard to deal with the issues that come up, I think it might be my salvation. I do hope so."
Old and Grey September 28, 2016
5 users found this comment helpful.
Nardil (phenelzine) for Depression: "Tried so many anti depressants from 1982 to present then finally looked up Nardil and asked my provider to please please try it as i am tired of going back and forth on the Old and the new medications. Started the titrade from 25 mg daily and up to 45mg twice daily with such a relief from years of depression and anxiety after diagnosed with PTSD. Felt best at the 90mg daily but now i notice the feeling is fading and I am wondering if the new batches are No good. I speak of food for myself as i eat anything that i want and have not experienced any negative feeling. Weight gain is a real negative especially in my gut and i can seem to get rid of it."
Navyman94 (taken for 2 to 5 years) August 13, 2016
18 users found this comment helpful.
Nardil (phenelzine) for Depression: "Ptsd anxiety, Lifted after 20 years of suffering and isolation. On 90 mgs daily 9 months feel like enjoying life. Have cheated and eat as normal, Inorgasm problem eased with concurrent 05 mg cabergoline gives multiple orgasm. Weight gain in stomach very disappointing."
Navyman94 August 6, 2016
10 users found this comment helpful.
Nardil (phenelzine) for Depression: "After trying every other kind of antidepressant over the past 9 or so years, Nardil was my first try at an MAOI. The dietary restrictions were less difficult to get used to and less strict than they appeared at first. I was on 30mg of Nardil a day and didn't notice any effect, but after increasing to 45mg/day, I felt the best I've felt in years and it seemed that my depression might be cured at last. ...however, I also had the most side effects I've ever had from a medication: constipation, difficulty urinating, insomnia, and inability to reach an orgasm. Because of the bladder issues and insomnia, I've been forced to resume my search."
BubbaTheBubbed (taken for 1 to 6 months) July 30, 2016
8 users found this comment helpful.
For Depression: "I have bipolar disorder that stays on the depressed side, so I also take 750 MG of lithium in addition to 60 MG of Nardil. I've taken every TCA, every SSRI, and SSNRI. I have AARP insurance, the add-on to Medicare. Nardil is a Tier 4 drug, about $95/mo. I've taken everything else, the drug was dropped to a Tier 1. I changed all my meds to Optum RX, and for 90 days of Tier 1 or 2 meds, I pay $0. Nardil is the most effective antidepressant I've taken. The dietary restrictions are not a problem, but I cheat and have coffee. The problem is the lack of coordination if you need elective surgery. Communication between the anesthesiologist, psychiatrist, retina specialist/surgeon, and 3 RNP's is pitiful. Anesthesiologist refuses to meet with me."
Retha1968 (taken for 1 to 2 years) April 9, 2016
4 users found this comment helpful.
Nardil (phenelzine) for Depression: "Been on Nardil for almost 20 years. Works well. I had severe panic attacks and couldn't even go out of the house. It can be annoying when you have a cold or flu but at least don't get depressed about it. Lol. Good thing the psychiatrist gave me that first so I didn't have to try others. I tell others about it so they can get their severe anxiety helped."
PanicNoMore January 7, 2016
36 users found this comment helpful.
Nardil (phenelzine) for Depression: "This medication is brilliant. Completely got rid of my depression and social phobia. I take 75mg/day. The SSRI's didn't really work. Was laying on the bed all day thinking of suicide and death. After I started Nardil my life completely changed. Thank goodness for the medication."
Andy12 September 3, 2015
42 users found this comment helpful.
Nardil (phenelzine) for Depression: "Nardil worked extremely well for my bipolar depression. It made a huge difference in my life. I find it very stimulating (I can't imagine what it would be on Parnate). I always have so much energy and I never feel depressed. However, it doesn't work as well for my anxiety."
JJGG April 18, 2015
25 users found this comment helpful.
For Depression: "Nardil was a last resort drug for me, after 25 years of trying anything, including a vagus nerve implant and electroconvulsive therapy to treat life-long major depression. I have never been sure if it works or not. I still have major depressive episodes - an increase in the medication seems to help. However, side effects such as fatigue to the point where I cannot take another step, hypomanic episodes, a feeling of "bugs" crawling on under my skin, and an 80 pound weight gain makes me want to stop taking the medication. I have stopped and restarted it a couple times over the past 6 years, and am unsure if it really helps or not. If you plan to start taking it, I would advise to keep track of side effects you might not relate to Nardil."
Parvatideva April 4, 2015
4 users found this comment helpful.
Nardil (phenelzine) for Depression: "Nardil works very well for my bipolar depression. I had hypersomnia when I was depressed and the drugs I tried (Lamictal, Zoloft, Celexa…) didn’t help at all. I’m glad my psychiatrist made me try this medication. At first, I took 45 mg, but after a while, it made me maniac. I had to lower the dosage to 30 mg and, surprisingly, it’s seems to be working (even though it’s not considered as a therapeutic dose). The diet is very easy to follow, as long as you can take bottled beer. The only downside is the sugar cravings, which are difficult to resist."
Bipolar12345 (taken for 1 to 6 months) March 8, 2015
27 users found this comment helpful.
Nardil (phenelzine) for Depression: "Diagnosed bipolar late 30's, lithium threw me into a clinical depression. Was not hospitalized as I tried tricyclic after tricyclic, with the awful side effects, weight gain and almost a zombie, sleeping all the time. Researching I discovered MAOI Inhibitors, was put on Nardil. Had only 15 min. medication checks every two weeks. At the first I asked, still depressed, "Will I ever be motivated again?", so weary was I of this horrid depression. At the second medication check, two weeks later, my depression had lifted! It kept me out of depression, functioning, and as close to 'normal', "whatever that is", for decades. It saved my life."
LLG (taken for 10 years or more) March 10, 2014
77 users found this comment helpful.
Nardil (phenelzine) for Depression: "Saved my life! Had major postpartum tried for 3 months on different antidepressants nothing worked until Nardil ! Thank you Nardil ..."
Bella taco February 7, 2014
49 users found this comment helpful.
Nardil (phenelzine) for Depression: "I am still on Nardil and waiting to wean off. My experience has not been great. It hasn't helped me with depression as it only has causes terrible adverse effects that has affected my life. I am depressed, angry, irritated, anxiety-ridden, just to name a few symptoms. My doctor is going to start getting me off it soon as he will try Nortripyline. It's true that Nardil works for a lot of people but not me. Just a terrible experience."
andrew811 (taken for 6 months to 1 year) November 2, 2013
30 users found this comment helpful.
Nardil (phenelzine) for Depression: "I was diagnosed with bipolar/severe mania and depression since I was 26, I have see every psychiatrist in my area, and have been put on every antidepressant from Paxil to Effexor. The only one that ever worked is Nardil. I am 33 years old now and would recommend this monoamine oxidase inhibitor to everyone who needs to be on an antidepressant. I was fortunate to find a very intelligent doctor who worked with me through these years. He told me not too many doctors prescribe Nardil for the food restrictions or whatever, but I personally believe the "old school" MAOI's are the way to go. Nardil gets a 10 in my book. I felt the ahhh, effects after one week."
beejholy July 7, 2013
84 users found this comment helpful.
Nardil (phenelzine) for Depression: "Have been depressed and anxious my whole life (now 44) and was undiagnosed. Was on Paroxetine for 10 years: life continued to turn to crap, wife left me, etc. Psychiatrist listened to symptoms and put me on 3 x 15mg Nardil. Still have suicidal thoughts and trouble with sexual function but it is definitely the medicine for me. Will stay on it for life if possible: at least I am still alive and food restrictions aren't that bad."
6shooter (taken for 2 to 5 years) January 6, 2013
59 users found this comment helpful.
Nardil (phenelzine) for Depression: "I took Nardil from '88-'98 and it worked well. Then I was switched to Paxil, which had a lot of side effects (weight, sexual, tired, sense of not really being there). Paxil was probably better for OCD but I came off it (had shocking withdrawal symptoms)."
Anonymous (taken for 10 years or more) August 11, 2012
26 users found this comment helpful.
Nardil (phenelzine) for Depression: "I took Nardil for 21 years. It worked better than anything else, until the dose was increased from 10 to 40 mg per day. None of my physicians were able to diagnose the cause of the grotesque swelling of my legs. A friend suggested it might be the Nardil; I quit taking it and proved her right. Even in reduced doses, the swelling persisted. I now take something else."
Lorrainecarole April 17, 2012
34 users found this comment helpful.
Nardil (phenelzine) for Depression: "I was on Nardil for over 20yrs until I was unable to get them on prescription anymore. I was then put on other antidepressants but none worked as well. I can now get the tablets again and have been on them for just 11 days. I am finding the side effects (nausea, loss of appetite) hard to deal with but trying to persevere with them as I know they are amazing when into system, and before while I was on it I was able to lead an almost normal life."
linje March 24, 2012
52 users found this comment helpful.
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- Drug class: monoamine oxidase inhibitors
Other brands: Nardil