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Selegiline Dosage

Medically reviewed by Drugs.com. Last updated on Aug 10, 2023.

Applies to the following strengths: 5 mg; 1.25 mg; 6 mg/24 hr; 9 mg/24 hr; 12 mg/24 hr

Usual Adult Dose for Parkinson's Disease

Oral capsule and tablet: 5 mg orally twice a day taken at breakfast and lunch
Maximum dose: 10 mg orally per day

Oral disintegrating tablet:

Maintenance dose: 1.25 to 2.5 mg orally once a day before breakfast
Maximum dose: 2.5 mg orally once a day

Comments:

Use: As an adjunct in the management of Parkinson's disease in patients being treated with levodopa-carbidopa who exhibit deterioration in the quality of their response to this therapy.

Usual Adult Dose for Depression

Transdermal System:
Initial dose: 6 mg/24 hours patch applied topically once a day

Maintenance dose: 6 mg/24 hours to 12 mg/24 hours patch applied topically once a day
Maximum dose: 12 mg/24 hours

Comments:

Use: Treatment of major depressive disorder (MDD)

Renal Dose Adjustments

Oral tablets: Data not available

Orally disintegrating tablets:


Transdermal patch:

Liver Dose Adjustments

Oral tablets: Data not available

Orally disintegrating tablets:


Transdermal patch:

Precautions

US BOXED WARNING (transdermal patch):


CONTRAINDICATIONS:
ORAL USE:
TRANSDERMAL USE:

Safety and efficacy have not been established in patients younger than 18 years.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Administration advice:
Oral capsule/tablet:

Orally disintegrating tablets:
Transdermal patch:

Storage requirements:

General:

Monitoring:

Patient advice:

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.