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Selegiline Pregnancy and Breastfeeding Warnings

Selegiline is also known as: Atapryl, Carbex, Eldepryl, Emsam, Jumex, Selgene, Zelapar

Selegiline Pregnancy Warnings

Animal studies have failed to reveal evidence of teratogenicity. Reproductive toxicity was seen at high multiples of human doses and developmental toxicity at doses greater than those used clinically. There are no controlled data in human pregnancy. AU TGA pregnancy category B2: Drugs which have been taken by only a limited number of pregnant women and women of childbearing age, without an increase in the frequency of malformation or other direct or indirect harmful effects on the human fetus having been observed. Studies in animals are inadequate or may be lacking, but available data show no evidence of an increased occurrence of fetal damage. US FDA pregnancy category C: Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

This drug is only recommended for use during pregnancy when benefit outweighs risk. AU TGA pregnancy category: B2 US FDA pregnancy category: C

See references

Selegiline Breastfeeding Warnings

Use is not recommended; a decision should be made to discontinue breastfeeding or discontinue the drug, taking into account the importance of the drug to the mother. Excreted into human milk: Unknown Excreted into animal milk: Yes

See references

References for pregnancy information

  1. "Product Information. Zelapar (selegiline)." Valeant Pharmaceuticals, Costa Mesa, CA.
  2. "Product Information. Eldepryl (selegiline)." Somerset Pharmaceuticals Inc, Tampa, FL.
  3. "Product Information. Emsam (selegiline)." Bristol-Myers Squibb, Princeton, NJ.
  4. Cerner Multum, Inc. "Australian Product Information." O 0

References for breastfeeding information

  1. Cerner Multum, Inc. "Australian Product Information." O 0
  2. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
  3. "Product Information. Eldepryl (selegiline)." Somerset Pharmaceuticals Inc, Tampa, FL.
  4. "Product Information. Emsam (selegiline)." Bristol-Myers Squibb, Princeton, NJ.
  5. "Product Information. Zelapar (selegiline)." Valeant Pharmaceuticals, Costa Mesa, CA.

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