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Carbidopa / Entacapone / Levodopa Dosage

Medically reviewed by Drugs.com. Last updated on Oct 4, 2024.

Applies to the following strengths: 12.5 mg-200 mg-50 mg; 25 mg-200 mg-100 mg; 37.5 mg-200 mg-150 mg; 50 mg-200 mg-200 mg; 18.75 mg-200 mg-75 mg; 31.25 mg-200 mg-125 mg

Usual Adult Dose for Parkinson's Disease

Converting from Carbidopa, Levodopa, and Entacapone:


Converting from Carbidopa and Levodopa:

Concomitant Administration with Other Anti-Parkinson Drugs:

MAXIMUM DAILY DOSE:

Comments:

Use: For the treatment of Parkinson's disease:

Renal Dose Adjustments

No adjustments recommended

Liver Dose Adjustments

Use with caution, especially in patients with biliary obstruction or hepatic disease

Dose Adjustments

Patients receiving less than 70 to 100 mg of carbidopa per day are more likely to experience nausea

Discontinuation or Interruption of Dosing:

Precautions

CONTRAINDICATIONS:


Safety and efficacy have not been established in patients younger than 18 years.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Administration advice:


General:

Monitoring:

Patient advice:

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.