Sinemet for Parkinson's Disease User Reviews

• Dot...
• Taken for 1 to 2 years
• April 2, 2014

"My mom just celebrated her 1-year anniversary on Sinemet, so I wanted to share an update to give anyone newly diagnosed hope. Her dose is now 4 tablets a day (25/100), which she takes at 9:00 am, 1:00 pm, 5:00 pm, and 9:00 pm. We increased from 3 tablets a day probably around month six, and she's been really doing well since then. No tremors, no obvious rigidity (or any Parkinson's symptoms at all), good appetite. Zero side effects from the Sinemet, which is why I say 'celebrated.' This is a remarkably effective and very affordable medication. Mom will turn 88 in May. Wishing everyone the success that we have had."

• Dot...
• Taken for 1 to 6 months
• March 28, 2013

"My mom has been on generic Sinemet for 8 weeks, and her improvement is remarkable. She's 86, and until the last 18 months, she had never taken any medication and was energetic and bubbly. She had a dramatic and fast onset of Parkinson's, and prior to starting this medication, she was almost completely debilitated. She looked like she was slowly dying. She lost a lot of weight, was shuffling, stooped in posture, exhausted, and confused. We took her to a neurologist who started the Sinemet slowly over a series of three-day incremental increases, and she started showing improvement almost immediately. She now takes 1 tablet three times a day (25/100). Zero side effects. And, now, two months into this, she's 75% back! It's a miracle!"

• Dot...
• July 18, 2013

"I wanted to share an update on my mom's status with the hope this information helps others. My mom's been on the Sinemet now for five months. She's still taking 3 tablets a day (25/100) -- one in the morning upon rising; one early afternoon and one in the evening. She's had no side effects that we are aware of, and up until the last three weeks has been really doing well. Now she's starting to have increased fatigue and some confusion -- not terrible, but noticeable. I'm talking to her neurologist in two weeks to see if she needs a small increase in her dose. He said her current dose (1 pill three times a day) is low, and there is room to increase gradually. Mobility is still excellent and tremors are barely there."

• Woo...
• March 19, 2018

"It stops tremors in its tracks. I know because I have Parkinson’s-like symptoms, and about four years ago, I had started the tremors or shakes. My ex-wife now made an appointment for me with a neurologist, and he prescribed me Sinemet 25/100s three times daily. But I still had a little tremor in my hands, so he added one more pill per day to my regimen of three per day to four per day, and that’s when the tremors stopped completely!!!"

• Har...
• Taken for 6 months to 1 year
• February 7, 2022

"I started on Sinemet about a year ago for stage 2 Parkinson's. Since I have been on this medication, my tremors and shuffling gait have improved dramatically. Before starting, my body movements were virtually uncontrollable. Now I can function almost normally. Sinemet also allowed me to return to work after being unable to work for about 8 months. Granted, I cannot do the same job I was doing (nurse), but I am able to work in an administrative function. A huge weight was lifted because of Sinemet..."

• Pau...
• Taken for 1 to 6 months
• February 18, 2018

"Since cutting my dosage of Mirapexin, which was causing me to sleep excessively, and using Sinemet, I feel a lot better. I had also gained 12 kilos while taking Mirapexin, which seemed to give me a sugar craving. I am not up to the full dose of Sinemet yet, but I am optimistic that I will lose the weight I have gained. Motor skills that I was told should return haven't as yet. Paul, 57, Sports Teacher. Brighton, England."

• R R...
• Taken for 6 months to 1 year
• January 20, 2017

"I have been taking Sinemet for more than 6 months. I started with 1 pill every meal (3 times a day), and then I went to two pills with every meal. I feel okay, except that I am having problems with my eyes. I see double sometimes. Furthermore, I have been afflicted with Stevens-Johnson Syndrome since the age of 19 years old. This causes dry eyes, plus I have eyelashes going inward, which does not help matters. I rated Sinemet an 8, but I am sure Sinemet is good for me since I no longer have the symptoms associated with Parkinson's disease. My problems seem to be associated more with my eyes."

• Rob...
• Taken for 2 to 5 years
• December 16, 2021

"I have been on Sinemet 12.5/50 mg taken 4 times a day for 22 months, but now my tremor seems to be getting worse. I have now started taking 5 pills a day, but this only makes the tremors worse and my lower jaw tremors. Advise anyone?"

• wv_...
• September 4, 2009

"Overall was an effective drug for me, but had problems with it wearing off between doses."

• Ano...
• Taken for 1 to 6 months
• April 29, 2018

"I took Sinemet for about a month, and while it lessened my uncoordinated hand movement, I fell into a very deep depression and was having panic attacks. As soon as I stopped taking it, I was better."

• mar...
• June 5, 2017

"Terrible depression, mood swings, not helping. Tremors seem the same as before I was taking them. Might ask the doctor to stop giving it one more week. I have been taking it for 6 weeks."

• Max...
• Taken for 5 to 10 years
• November 22, 2021

"I have been okay on this. Now getting wear off quickly. But would recommend trying."