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Entacapone Dosage

Medically reviewed by Last updated on Oct 16, 2023.

Applies to the following strengths: 200 mg

Usual Adult Dose for Parkinson's Disease

200 mg orally concomitantly with each dose of levodopa-carbidopa up to a maximum of 8 times a day
Maximum dose: 1600 mg per day


Use: As an adjunct to levodopa-carbidopa to treat end-of-dose "wearing-off" in patients with Parkinson's disease.

Renal Dose Adjustments

No adjustment recommended

Liver Dose Adjustments

Dose adjustment may be required; however, no specific guidelines have been suggested. Caution is recommended.

Dose Adjustments

When discontinuing therapy, monitor patients closely and adjust other dopaminergic treatments as needed; no specific dose reduction is recommended, although tapering seems prudent.


Safety and efficacy have not been established in patients younger than 18 years.

Consult WARNINGS section for additional precautions.


Data not available

Other Comments

Administration advice:



Patient advice:

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.