Entacapone User Reviews & Ratings

Brand names: Comtan

Entacapone has an average rating of 4.6 out of 10 from a total of 14 reviews on Drugs.com. 36% of reviewers reported a positive experience, while 50% reported a negative experience.

Condition	Avg. Rating	Reviews	Compare
Parkinson's Disease	4.6	14 reviews for Parkinson's Disease	52 medications
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Reviews for Entacapone

Arnold
Taken for 6 months to 1 year
February 16, 2020

Comtan (entacapone) for Parkinson's Disease "Sinemet 25/100 6 x daily 1 tabs with 100 mg Comtan 6 x daily with my Sinemet Not working well. Off times between medication 1.5 to 2 hours off times x 6 daily between medication. Experience bad nightmares Nauseous Involuntarily movements Muscle pain Stiffness Difficulty breathing Weak Low concentration span Can not see any positive results taking this medication "

1 / 10

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28 Report

Grammie
Taken for 1 to 6 months
December 29, 2020

For Parkinson's Disease "I have taken Entacapone for about five months now I have just about every negative side effect there is. I am lightheaded dizzy unsteady and I’m not sure it’s working as well as it should I feel like I’m living in a fog, so unsteady I can’t do much for myself. I was afraid of falling so must always hold onto something. I understand it’s not safe to go off of it I’ve only taken half the dosage since I started my body won’t tolerate anymore. At first it was doing its job now I have to take levodopa more often I am going to speak to my doctor in a couple of weeks to see what he can do about it. It has affected my vision to the extent that I have to dictate everything and can’t text this Christmas holidays. Right now I simply can’t tolerate it any longer and I don’t know what to do. Horrible stuff."

5 / 10

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18 Report

mjbaz
Taken for less than 1 month
June 17, 2017

Comtan (entacapone) for Parkinson's Disease "Didn't improve any symptoms. Side Effects: 1. It was messing up my stomach and starting to cause problems with my acid reflux 2. I had several episodes of feeling really anxious and my heart would race – on the verge of panic attack, maybe? 3. Very slight fear of the dark"

1 / 10

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23 Report

Athenz
May 31, 2020

For Parkinson's Disease "I am younger than most individuals diagnosed with parkinson's and am considered mild to moderate. I have regular exercise everyday and just started on Entacapone this past week. Though it is quite early I am hopeful that it will work continuously. It has lengthened my window of on time up an hour yesterday and today but, is inconsistent possibly due to that it may take time to establish the Entacapone in my system. So far I have had no adverse effects other than noticing I do get sleepy but, my doctor has said that many individuals can take entacapone well. I have not had any constipation or hallucinations and follow this medicine carefully. I just bought a medicine timer to keep myself on a strict regiment. I will keep you posted from time to time and hope that others do well on this. Mine is the generic form and I have Medical and so I am lucky it's not expensive for me. Thank you"

8 / 10

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15 Report

Anwar
August 30, 2021

For Parkinson's Disease "Taking it for nearly 2 week after consulted with my neurologist to substitute from Sifrol. My body feels very stiff till had to drag my feet to move, anxiety sky rocket, fear...the only good thing of it is i gained back my smell sense. Of course pain....will stop using it today..."

2 / 10

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10 Report

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Stay...
Taken for less than 1 month
April 11, 2017

Comtan (entacapone) for Parkinson's Disease "I just started taking this drug about 3 weeks ago. The first week was a little rough and it leaves a funny taste in my mouth. However, now that I am getting used to it, I find it helpful. I can take less Carbidopa/Levodopa and has much smoother transition between end/begin of medication times. ONE THING I HAVE FOUND is the importance of staying hydrated. Dehydration is a side effect and it shows. If I don't watch it, I start feeling bad & symptoms flare up. After I drink a large glass of water, I start feeling better."

8 / 10

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20 Report

Ho-Hum
February 16, 2012

For Parkinson's Disease "Pros: Greatly reduces tremors and lasts up to the next scheduled dose, which is the point of taking the medicine. However..... Cons: Immediately after taking the drug, there is temporary nausea, drowsiness, sleepiness & disorientation, dizziness. It makes me sleep more than desired. I can no longer drive, cook, or do much of anything because of the dizziness. I prefer tremor relief, so the medicine wins. We don't have much choice with this disease. It's very expensive, but what is your quality of life (what little there is) worth to you? If I have to exist, I would rather sleep than suffer tremors most of my waking hours."

7 / 10

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26 Report

Anonymous
Taken for 1 to 6 months
July 3, 2021

For Parkinson's Disease "I am in my 9th year of being diagnosed with Parkinson's I have been taking entacapone with my carbidopa / levodopa for a few weeks now and it has helped me tremendously. My good times last longer and I was telling my doctor that quite often during the day I almost forget that I have Parkinson's. My wife has noticed the difference in my stance and the less shaking. One side effect that is not so welcome is the constipation, however beans on toast and water fix that !"

9 / 10

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7 Report

Tracy...
Taken for less than 1 month
September 26, 2022

For Parkinson's Disease "Entacapone almost immediately helped by taking away all symptoms of off time. HOWEVER my mood throughout the day became worse and more irritable . I felt a total disconnect from my loved ones. By bedtime I was a monster of anger. After 5 days I decided the trade off was not worth it. So I'm back to my off times . Better than losing my relationships."

3 / 10

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3 Report

Anonymous
Taken for less than 1 month
October 11, 2021

Comtan (entacapone) "Comtan worked well on my restless leg syndrome. I didn't have to get up in the middle of the night to go to the bathroom, and I was able to sleep for seven hours straight. I never can do that with generic Sinemet because it wears off too soon. I wish I could get a prescription for it instead of just the samples given to me by a neurologist."

10 / 10

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2 Report

pug
Taken for less than 1 month
May 5, 2019

For Parkinson's Disease "Entacapone has caused nightmares which greatly interrupted my sleep. Stopped taking after 3 weeks. I am now sleeping much better"

3 / 10

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16 Report

JJano
Taken for less than 1 month
February 9, 2021

For Parkinson's Disease "Just been taking entacapone (200 mg) 3 times a day with carbadopa for 4 days. I have become quite sleepy throughout the day accompanied with disorientation and increasing balance issues."

3 / 10

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10 Report

Anonymous
June 8, 2010

Comtan (entacapone) for Parkinson's Disease "Terrible hallucinations!"

1 / 10

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29 Report

Bmp
April 11, 2012

Comtan (entacapone) for Parkinson's Disease "I take Sinemet 25/100 4 x daily 1 1/2 tabs with 100 mg Comtan 4 x daily with my Sinemet and it seems to work well for lessening my "wear off" periods but it does cost a lot."

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25 Report

Shirley...
April 28, 2008

Comtan (entacapone) for Parkinson's Disease "The medication is very good. Unfortunately it is expensive"

9 / 10

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25 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.