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Rasagiline Dosage

Medically reviewed by Last updated on Sep 12, 2023.

Applies to the following strengths: 0.5 mg; 1 mg

Usual Adult Dose for Parkinson's Disease

Recommended dose: 1 mg orally once a day

Adjunct therapy:
Initial dose (in patients on concomitant levodopa): 0.5 mg orally once a day
Initial dose (in patients not on concomitant levodopa): 1 mg orally once a day
Maintenance dose: 0.5 mg to 1 mg orally once a day

Maximum dose: 1 mg orally once a day

Comments: May be used as adjunct therapy in patients on levodopa therapy, with or without other drugs used in the treatment of Parkinson's disease.

Renal Dose Adjustments

Mild to Moderate Renal Dysfunction: No adjustment recommended
Severe Renal Dysfunction: Data not available

Liver Dose Adjustments

Mild Liver Dysfunction (Child-Pugh 5 to 6): 0.5 mg orally once a day
Moderate to Severe Liver Dysfunction (Child-Pugh 7 to 15): Use is not recommended

Dose Adjustments

Concomitant CYP450 1A2 inhibitors (e.g., ciprofloxacin): A dose of 0.5 mg orally once a day should not be exceeded.

When this drug is used in combination with levodopa, the levodopa dose may need to be reduced, according to clinical response.


Safety and efficacy have not been established in patients younger than 18 years.

Consult WARNINGS section for additional precautions.


Data not available

Other Comments

Administration advice:



Patient advice:

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.