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User Reviews for Benadryl

The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care.

Learn more about Benadryl.

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Condition DownUp Reviews Compare Avg. Ratings DownUp
Cold Symptoms 2 reviews 1080 medications
   
9.3
Cough 2 reviews 795 medications
   
9.0
Urticaria 2 reviews 189 medications
   
8.5
Nausea/Vomiting 10 reviews 160 medications
   
8.0
Allergic Reactions 12 reviews 187 medications
   
7.4
Allergic Rhinitis 10 reviews 886 medications
   
6.5
Extrapyramidal Reaction 1 reviews 68 medications
   
5.5
Summary of Benadryl reviews 39 reviews 7.7

Reviews for Benadryl

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For Nausea/Vomiting "ER gave me 25mg diphenhydramine IV for nausea. The only effect was delirium and a brief medication nap. I felt woozy and poisoned for at least two hours afterwards. It may work for others, but it certainly didn't help me."

   
3.0

Simon Charles (taken for less than 1 month) September 14, 2017

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For Nausea/Vomiting "I take Methotrexate weekly 25mg and have found that taking Benadryl at dose and 12 and 24hrs after my weekly dose help reduce the nausea"

   
8.0

Anonymous September 2, 2017

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For Allergic Rhinitis "I have a lot of allergies. About a year ago I began taking benadryl at night to help me sleep. It also helped a lot with the allergies. I only take it at night because of the drowsiness. Recently my stomach was upset for a month and I noticed they've begun putting calcium in it! This is so upsetting! Calcium stimulates stomach acid and people with allergies are sensitive to acid. This has been documented in the allergy journal. I would have thought a pharma company would know better than this! I wish the two corp. drugstores in my area had a better selection of drowsy antihistamines. They mostly have only benadryl. CVS has chlorphen, but it has lactose in it. :( For now I'm making do with a Walgreens combo that includes chlorphen."

Julia372 July 21, 2017

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For Allergic Reactions "I have no rest every time I take benadryl. I feel I have a really bad reaction as I feel restless, my body feels like itchy, nauseous and it makes me feel angry feeling restless it really hurts my stomach am I allergic to it? or it a bad reaction"

Connert2 April 26, 2017

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For Urticaria "I was diagnosed with Chronic Idopathic Angioedema in 2005. I was 8 months pregnant and woke up one morning and my face was unrecognizable. I called my Dr and they said "oh it's probably just pregnancy swelling". I am an only child so I didn't know about facial swells. My husband came home and said this is NO pregnancy swelling. This was in 2003. It continued weekly so we took pictures and took to my obgyn. He had been practicing medicine for over 30 years and never seen anything like it, I saw numerous Dr.s and was finally diagnosed. I was in the hospital and swelled up I was given over Benadryl. It took my breath away and couldn't speak. Another nurse came in and yelled at the nurse. It has 2 b given slow or its very dangerous"

   
7.0

Chronic Idopathic Angeodiema (taken for 5 to 10 years) December 1, 2016

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For Allergic Rhinitis "I been up since12 pm with hay fever took a benadryl then couldn't stop sneezing due to hay fever nasal passages swollen and can't breathe it doesn't make me sleepy at all and my nose is still stuffy its is now. 3am I'm still up suffering with hay fever and just took another benadryl smh .not working fast enough for me plus I suffer with hay fever really really bad"

Anonymous (taken for 1 to 6 months) October 21, 2016

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For Allergic Reactions "My adult size teenage son was given Benadryl IV, 50mg, *along with Compazine IV as a "headache cocktail" in an emergency room in September of 2016. While there is no way to know for certain if Compazine or Benadryl caused the severe reaction he experienced, he has tolerated oral Benadryl just fine in the past. However, it seems important to share our experience based on the severity of his reaction that day and that multiple reports of similar exist. I do not recommend the "headache cocktail" of Benadryl and Compazine together and hope the number of similar reports are looked into."

   
6.0

Son, age 16 (taken for less than 1 month) October 15, 2016

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For Urticaria "I would get so worked up with hives before an exam with my gynecologist, that I would have to cancel. One day I took a Benadryl (they usually come in 25 mg or 50 mg tablets, or in packs of two 25 mg tablets)- just 25 mg before my appointment, and it really took the edge off. I had no hives and was much more relaxed. I buy the generic brand at the Dollar Store. This is used in our house for insomnia, allergic reactions, stuffy noses, and what I had previously mentioned. It is not habit-forming, and at such low doses, it's easy to control. Just make sure you stay hydrated! One word of caution to parents with young kids or teens- there have been many cases of suicide attempts and to trip out on."

   
10

Nurse-student July 11, 2016

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For Nausea/Vomiting "I had a couple surgeries on my jaw where I could not open it fully for an extended period of time. I am already semi-allergic to pain meds / anesthesia (excessive vomiting and nausea) so I was terrified to take my pain killers after surgery. The nurse / doctor recommended taking a couple Benadryl tablets (25mg) before the pain meds and it worked wonders! The only side effect is drowsiness."

   
10

MarD24 June 5, 2016

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For Allergic Rhinitis "Good antihistamine. Can cause drowsiness, but it works quickly and shrinks nasal swelling better than some of the other choices. I take a newer antihistamine during the day, but this helps a ton at night when the other wears off and the pollen is still bad."

   
8.0

NCResident (taken for 5 to 10 years) May 23, 2016

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For Allergic Reactions "I take one before bed which keeps me breathing easily during the night despite my allergies. It also helps me get to sleep and stay asleep. The active ingredient, dyphenhydramine HCL, you will find is the main ingredient in quite a few over the counter sleep medications so that should tell us something. And Benadryl or a generic drugstore brand are cheaper and just as effective. Have been taking this for over 20 years and have no side effects"

   
9.0

Amensus (taken for 10 years or more) April 28, 2016

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For Allergic Reactions "Best drug for me to wake up with good sleep and not have a headache. I have used it for 8 years for allergies (itchy eyes, bug reactions) and my house always has it in stock. Love the drug!"

   
10

Allergic Headaches/can't sleep (taken for 5 to 10 years) April 20, 2016

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For Allergic Rhinitis "Works better then most prescription drugs for allergies and chronic sinusitis ( I've had sinus surgery 4 times due to this), whose side effect are health threatening. I will only take at night due to the drowsiness, this drowsiness can turn into nervousness if I don't fall asleep and keeps me up all night. I do have drowsy days often with naps from sitting and just passing out. I find that if continue taking every night about the fourth I begin to have vivid and horrible nightmares. I also get drenching night sweats - the two are not always together one night I may have one or the other. I take one (1) tablet."

   
8.0

707 NC (taken for 2 to 5 years) March 8, 2016

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For Allergic Rhinitis "experienced very low heart rate, palpatations, very disoriented, drowsy after taking only one 25 mg pill"

   
1.0

grandynandy March 2, 2016

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For Allergic Reactions "Allergy reaction to nuts. Started feeling swelling around mouth, throat.... very scary, feel like I am stopping to breath. This instant relieve. Give it 10-15 minutes till kicks in. WORKS WONDERS. BUT.... you might need a good snooze after a good dose..."

   
10

Madam2 January 25, 2016

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For Nausea/Vomiting "I get severe migraines and was given this in the hospital instead of traditional nausea meds. It work well and I now use it at home and actually works better than Zofran or Phenagren."

   
10

Mmwillis December 29, 2015

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For Nausea/Vomiting "I got a severe back injury about 2 years ago. Couldn't function pain was so bad. So my doctor started putting me on codiene, then vicoden, then tramadol, and then so on but they all gave me hours of vomiting, gut wrenching cramps, and sweating. Read about benadryl being used to prevent this side effect. I took 3 25 mg tabs. I know that is one over recommended but I was desperate. 35 mins later I was sitting with my kids and not the trash can for the first time in a while. I can't believe I didn't figure this out sooner especially with a biotech degree."

   
10

A biotechnologist. (taken for less than 1 month) December 20, 2015

38 users found this comment helpful.

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For Nausea/Vomiting "I have Cyclic Vomiting Syndrome and take Benadryl everyday. It helps take the edge off. There are less side effects than other anti nausea medications and is safest for the body."

   
9.0

Andy D November 24, 2015

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For Nausea/Vomiting "I use it for nausea. It works wonders for me."

   
10

works! (taken for 10 years or more) October 2, 2015

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For Allergic Rhinitis "Very sensitive to medication. Can not take histamines. Finally have outgrown allergies. Off and on about 20 yrs."

   
4.0

OAIAB January 25, 2015

7 users found this comment helpful.

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For Extrapyramidal Reaction "Diphenhydramine definitely calms down my muscles and helps with any antipsychotic induced akathesia at night. Great for sleep as well and helps me stay in bed in the mornings, but I'm able to get up early if I need to."

   
9.0

robertocsada (taken for less than 1 month) January 12, 2015

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For Nausea/Vomiting "Great for nausea. However does cause sleepiness."

   
9.0

cd101617 (taken for 1 to 6 months) November 30, 2014

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For Allergic Reactions "I was given Benadryl at the hospital for an allergic reaction. It instantly shot my heart rate up to 217 bpm and instantly my mouth got dry I couldn't swallow my chest felt hot like an elephant was sitting on it and I got really cold. It put me into shock my body wouldn't stop shaking, I could breath. It was so scary I thought I was dead thanks to the doctors quick response he saved me but it almost killed me. "

   
8.0

use caution when taking October 28, 2014

17 users found this comment helpful.

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For Allergic Rhinitis "Benadryl knocks all my symptoms out, the only problem is it can knock me out too but when nothing else works, Benadryl will do it. It's cheap, effective and available in every store."

   
10

Leelo (taken for 10 years or more) March 19, 2014

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For Nausea/Vomiting "I have emtophobia, that is, a pervasive fear of vomiting. I do not know if this affects vomiting, but if I feel nauseous, Benadryl works wonders. My stomach settles right down and my anxiety lowers just enough for me to deal with it without the use of benzodiazepines."

   
7.0

Anonymous June 15, 2012

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