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User Reviews for Cyproheptadine

Cyproheptadine has an average rating of 8.2 out of 10 from a total of 195 ratings on Drugs.com. 76% of reviewers reported a positive experience, while 10% reported a negative experience.

Condition Avg. Rating Reviews Compare
Anorexia  
8.6
130 reviews 3 medications
Migraine  
6.8
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Allergic Reactions  
9.0
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Failure to Thrive  Off-label
7.3
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Cluster Headaches  
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Sexual Dysfunction, SSRI Induced  Off-label
8.5
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Anorexia Nervosa  
5.5
2 reviews 1 medications
Urticaria  
8.0
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Allergic Rhinitis  
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Summary of Cyproheptadine reviews 8.2 195 reviews

Reviews may be edited to correct grammar/spelling, or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published.

Reviews for Cyproheptadine

Julia · February 9, 2020

For Anorexia: “I am a very slim girl. 21 years old. Normally 100-110 pounds. unhappy with my current weight. I didn't have an appetite much and feel very full with just a couple bites. I started cyproheptadine 2/3 weighing 106 lbs. today 2/8 I am 111.5 lbs. The first 3-4 days the pill makes you very very sleepy. Fight through it, as it goes away after the first few days. Cyproheptadine does make you feel super hungry and removes the full feeling. You must eat if you want to gain weight. I am taking the pill 2-3 times a day. 4mg. I do believe this does work. I will post more updates in a month.”

7 / 10
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Anonymous · Taken for 2 to 5 years · October 3, 2020

For Anorexia: “Hey guys, I had done a review on Cyproheptadine a few years ago. I was soooo excited about this pill and how it helped me gain weight but with the weight gain came a lot of other health issues that followed. I decided I needed to let you guys know what can happen to you too. I got addicted to the pills. I was always sleeping, not concentrating and the pills were not as effective as they were the first few month but I couldn’t stop taking them. It cause me to get fungus on my nails, breathing became heavy and I was always tired and sleepy. I decided to stop taking the pills which was very hard for me but I knew if I kept taking them I would end up getting really sick which my body was already showing symptoms of. All the weight shed after I stopped taking the pills, but I have learned to love my body. Being tired and experiencing health complications is not worth it. If you are not prescribed these from a doctor don’t mess with your body and your health guys!”

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D123 · Taken for 2 to 5 years · March 20, 2021

For Anorexia: “I took GML-apeti which has cyproheptadine in it, to gain weight. I gained about 35 pounds over a corse of 3 years. I noticed when I’d miss a pill or 2 I’d get dizzy and I was always tired on it. Then once I stopped taking it completely I couldn’t sleep, I woke up nauseous every morning, and now I have permanent dizziness which I believe is from taking that. I stopped over a month ago and I’m still sick. Ever since taking these pills I’ve developed horrible health conditions and I lost almost all the weight I’ve gained. Don’t take this....”

1 / 10
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Cece985 · June 29, 2014

Periactin (cyproheptadine) for Anorexia: “This medicine is exceptional! I see many people saying they gained 1-5 lbs, I took it faithfully, three times a day and would you believe I moved up from a 7/8 to a 9/10 and put on about 22 lbs within only 4 wks. I stopped for about 2 wks, lost about 6 lbs(mainly stress) but I'm back on them and sleeping a little more, but it only took about 2-3 wks for my body to get used to them. If you wish to gain weight try this! You will cry tears of joy I was struggling with weight gain for about 5 yrs!”

10 / 10
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fabulous40 · Taken for 1 to 6 months · July 19, 2014

Periactin (cyproheptadine) for Anorexia: “I have been looking for a long time a pill that would help me gain weight. Its not like was unhappy with the way I look but just wanted to add some curves. My daughter has been taking the pill and she was a lot smaller than me and she is looking great now. It does make you a little sleep at first but your body will start to get adjusted to it. I highly recommend this pill for weight gain. I just love and one pill a day will do the trick!”

9 / 10
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Girl · Taken for less than 1 month · February 6, 2020

For Anorexia: “I’m on my second week and I honestly don’t know if it’s working. Can someone tell me when it’s suppose to “kick in”? I have been eating more but only because I’m kinda forcing myself to since I think it’s what I’m suppose to do. Kinda like a placebo effect. I don’t feel any hungrier or anything. I’d like to gain at least 10 pounds I’m 18 years old and 97 lbs. Desperate at this point someone give me advice.”

6 / 10
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KK · March 19, 2020

For Anorexia Nervosa: “Started cyproheptadine mid September of 2019 at 97lbs. Underweight for a 31 year old woman. I’ve been small my whole life, but I am a very anxious person. So this was a contributing factor. My doctor prescribed 4mg 3 times a day. I started out with 1 pill a day and never increase because of how well it worked. The first week it does make you very sleepy and even irritable. Well it with with me. I pushed through because I needed to see if it worked. So my weight and dates. Started mid September 2019-97 lbs. October 7th- 110 November 6th- 121.2 I was gaining pretty decent weight and now I’m 136-139 which is at my goal since I’m only 5’1. My weight does fluctuate by 5 lbs give or take just depending how I’m feeling and eating. If I drop below 135, I just start it back and within a week and a half I’m back to where I want to be. This medication does work and it works well, the key is getting through the first week or two of side effects to allow your body to adjust.”

10 / 10
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Sharna1994 · January 24, 2021

For Anorexia: “I need advice I don’t know if anyone can reply back to me on here I’m new I took this drug for 5 years on and off to gain weight and my body became tolerant to it has anyone found another drug to help them gain weight my metabolism is very high and I suffer from dairy and sugar intolerance so it’s very hard for me to gain weight”

10 / 10
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TIffi3 · December 14, 2015

Periactin (cyproheptadine) for Anorexia: “On periactin (cyproheptadine) pills 3X pr day since 11/22/15 since then I have gained 22 pounds as of 12/13/15. These pills work wonders for people with poor appetite and eating habit. Being small most of my life I never thought it was possible for me to get over 110 pounds but these pills had me eating whole cakes in one day lol I'm so serious I eat two big macs instead of one with extra mac sauce lol, just everything and a lot of it. I'm lovin the way this 132 looks on me at 5t 3in...”

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pat · Taken for less than 1 month · September 16, 2019

For Anorexia: “Ok people why is cyproheptadine not working for me? This is my second week and I can't even tell that I am taking it. I take 4mg 3 x a day . Before breakfast-lunch-dinner. Please can someone recommend anything else or tell me what I am doing wrong. I was taking Megace gained 20 pounds but I started getting acid reflux and a raw tongue now I can't take that and lost down to 100lb so the Dr. gave me cyproheptadine. But it is not working I do not get hungry and I do not want to eat. Please any suggestions would help!!”

3 / 10
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Trixie777 · January 8, 2013

Periactin (cyproheptadine) for Anorexia: “I am 5'7" weigh 109lbs and had three kids over 8lbs. I am anorexic and had been doing everything to maintain a healthy weight. When I started taking Periactin (cyproheptadine), I was gaining 1-2 lbs a day. The only problem is that 3/4 of my day I was sleeping, had dry mouth and very bad mood swings. Due to my heavy work schedule it was hard to continue taking the pills. When I stopped, I lost the weight as quick as I gained it. 4 days ago I started taking it again and gained 5 lbs. This time once I reach my target weight of 130, I will set aside a meal plan to maintain this weight in addition to taking only 2 pills a week. I would highly recommend this medication to anyone who suffers from anorexia or had no appetite.”

10 / 10
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A m a z i n g · June 2, 2017

Periactin (cyproheptadine) for Anorexia: “This is simply something magical! I've been underweight naturally since the childhood, always been hearing "you should eat more" although I really had a good appetite. I even can't wear the clothes I want as I feel so bad to see my skinny legs, hands, etc. I sat at night and been thinking what else I can try to put on weight as protein milkshakes, squats didn't work for me. I googled out periactin, ordered online from Weldricks (UK) and I want to cry and scream the world how happy I am! Using for two weeks, 1 tablet before bedtime - gained 4kgs, never had this weight before! I eat like 3000-4000kcals a day. It also makes me feel really sleepy and tired but it means nothing when you see those amazing numbers on the scales.”

10 / 10
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JoJay · June 29, 2014

Periactin (cyproheptadine) for Anorexia: “All my life I have struggled to gain or maintain my weight. There are periods when I have no appetite. Can go for days and not eat and not get hungry. This medication has been a God send. At first the drowsiness was almost debilitating. After reaching my desired weight, I found that dropping the dose to 1/4 tablet per day kept it on but without the side effects. My son suffers from the same thing and he is now on it too. I highly recommend it to anyone wanting to gain weight.”

10 / 10
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maslar01 · October 3, 2013

Periactin (cyproheptadine) for Anorexia: “I am a retired physician who during the course of his practice treated many patients with severe anorexia secondary to HIV/AIDS as well as near end stage malignancies. For many years I prescribed Periactin starting with the 2mgm dose 1/2 to one hour before meal time. Many patients reported a robust weight gain. The hypersomnolence (excessive sleepiness) disappeared after one to three months. The Periactin can be reduced to one 2mgm every third day and the weight usually is maintained at good if not optimal levels. ”

9 / 10
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Butterflies1234567 · Taken for less than 1 month · March 2, 2017

Periactin (cyproheptadine) for Anorexia: “I decided to try this to put on weight. Its only the second day and I've noticed an extreme increase in appetite!!! The only bad thing is it makes me soooooooo tired does anyone else get this?? Shall I take it before bed then?”

6 / 10
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Sweet Pea · February 7, 2019

For Anorexia: “I waa prescribed this medication, little than 2 months ago due to me not having any type of appetite and I swear, these are miracle pills, lol. They really work I've been having the appetite of a grown man. I started off at 86 pounds, soaking wet... I'm now, 101lb so I gained... 15lbs, wow!!!!! Highly recommended...”

10 / 10
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CiCi · Taken for 1 to 2 years · November 2, 2018

Periactin (cyproheptadine) for Anorexia: “I've had problems with my weight all my life due to depression and anxiety. I would literally go days without eating. I started taking periactin about a year ago and it worked great! I ate multiple times throughout the day. I stopped and lost all of the weight I gained. I started taking them again 2 weeks ago and I've gained over 10 pounds already. I get sleepy but it's tolerable.”

10 / 10
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madame · October 1, 2011

Periactin (cyproheptadine) for Anorexia: “Periactin (Cyproheptadine) is amazing for weight gain! I gained so much weight and I looked amazing, however there were three side effects 1) I slept like a bear, I was always tired 2) I had really bad mood swings, and I was like a zombie 3) dry nose bleeds. However I reduced the dosage from 2 tables (one in the morning, one at night) to one a day and I felt much better. I recommend you take multi-vitamins and do lots of exercise. The results were quick and amazing, I would recommend it to anyone who wants to gain weight.”

10 / 10
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kkbaby · Taken for 1 to 6 months · July 9, 2019

For Anorexia: “Cyproheptadine is a miracle as an appetite stimulant. I listed Anorexia as my reasoning, although I did not actually have anorexia, because my doctor prescribed it as an appetite stimulant. I hadn’t been able to eat an entire meal in months due to my appetite being practically non existent. When I first went on cyproheptadine in January, I weighed 97 lbs. I was up to 112lb lbs by February 28th and officially had a “healthy” BMI! I got to about 115lb in March and tapered off to only taking it 2 times a day instead of 3 to maintain the weight and stop gaining as much. I have never felt better and finally eat like a normal person again”

10 / 10
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mrsellis221 · May 18, 2016

Periactin (cyproheptadine) for Anorexia: “I. Take this medicine everytime I have a poor appetite and it works wonders! I have always striggled with gaining and maintaining weight all my life! Got teased a lot! I have gained as much as 35 pounds in a month and a half! I recently just started back taking due to foot surgery and being on narcotic pain pills that stripped my appetite! The great thing about them is the weight and appetite stays even once you stop taking thrm! Highly recommemd”

10 / 10
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loving me · September 5, 2015

Periactin (cyproheptadine) for Anorexia: “I am 5'8 and when I started taking those pills cyproheptadine (periactin) I was 115. My Dr gave me the prescription on a Monday and told me to take then and come back on the following Monday. I took 1 each day for that week and when I went back to my Dr I weighed 130. He said that this was impossible. He thought that scale had broken lol. I was extremely excited. I would most definitely 100% recommend it”

10 / 10
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Emiwag · September 5, 2016

Periactin (cyproheptadine) for Anorexia: “I've always been underweight and I had a weak appetite and always struggled to gain any weight. I was 24 and still weighed 90lbs I was depressed about my weight. but after prescribed periactin, I gained over 15 lbs in 2 months and I feel great! I have never weighed over 100 lbs in my entire life. It really works!”

10 / 10
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Melisa7 · January 25, 2015

Periactin (cyproheptadine) for Anorexia: “I've always been very thin, and I disliked the way I looked in the mirror for years. Then 3 years ago my mom introduced me to this medicine, it worked wonders for my body. It stimulated my appetite, mad me sleepy which was good since I had problems sleeping and this medicine changed the way I looked. I was curvy and attractive, I took one pill every day or sometimes every other day and I moved from a size 0 to a beautiful size 6 and I was very happy with myself. The sad thing is I'm in China for one year doing my postgraduate degree and the stresses of being here have pulled my weight down to 8kgs less to where it was when I first came here. ”

10 / 10
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Khantrell · October 16, 2015

Periactin (cyproheptadine) for Anorexia: “Was very under weight for my age. Started taking these to help with it and be healthier. I was 102 and I went to 158 in about 2 months. It's been almost a year and I chose to lose some of the weight and I'm down 8 lbs but weight still here. I have a lot of curves now. Side effects is sleepiness but I started cutting my pills in half and that helped a lot. I would take half a pill every 2 hours taking 2 pills a day and then cut back to one whole a day after weight started coming on fast.”

10 / 10
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TinkaBellz · Taken for less than 1 month · August 27, 2016

Periactin (cyproheptadine) for Anorexia: “I have always been thin my whole life & tried everything to gain weight i hate skinny jokes still at the age of 31 & you would think 5 kids wouldnof gavr me some weight smh no so i ask my doctor to prescribe me something so far i been using them for 2 weeks now and I've went from 100 to 112. I suppose to take one at bedtime but I take them 2/3 times a day and it literally increases my appetite which I barely had before. Like I'm hungry all the time especially when I wake up in the morning and after dinner its a must for a late night snack/ mini meal... I'm really satisfied with my results my only complaint would be the sleeping so much I had to start taking half and half of the 4mg because they knock you out for hoursss. Hope this helps :-)”

10 / 10
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This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge and judgement of healthcare professionals.