Cyproheptadine Dosage
Medically reviewed by Drugs.com. Last updated on Oct 22, 2018.
Applies to the following strengths: 4 mg; 2 mg/5 mL
Usual Adult Dose for:
- Allergic Reaction
- Allergic Rhinitis
- Pruritus
- Urticaria
- Anorexia Nervosa
- Cushing's Syndrome
- Cluster Headache
- Migraine
Usual Pediatric Dose for:
Additional dosage information:
Usual Adult Dose for Allergic Reaction
Initial dose: 4 mg orally three times a day
Maintenance dose: 12 to 16 mg/day, occasionally up to 32 mg/day but not to exceed 0.5 mg/kg/day
Usual Adult Dose for Allergic Rhinitis
Initial dose: 4 mg orally three times a day
Maintenance dose: 12 to 16 mg/day, occasionally up to 32 mg/day but not to exceed 0.5 mg/kg/day
Usual Adult Dose for Pruritus
Initial dose: 4 mg orally three times a day
Maintenance dose: 12 to 16 mg/day, occasionally up to 32 mg/day but not to exceed 0.5 mg/kg/day
Usual Adult Dose for Urticaria
Initial dose: 4 mg orally three times a day
Maintenance dose: 12 to 16 mg/day, occasionally up to 32 mg/day but not to exceed 0.5 mg/kg/day
Usual Adult Dose for Anorexia Nervosa
Initial dose: 2 mg orally four times a day
Maintenance dose: may increase gradually over 3 weeks to 8 mg orally four times a day
Usual Adult Dose for Cushing's Syndrome
Initial dose: 2 mg orally four times a day
Maintenance dose: may increase gradually over 3 weeks to 8 mg orally four times a day
Usual Adult Dose for Cluster Headache
4 mg orally four times a day
Usual Adult Dose for Migraine
4 to 8 mg orally three times a day
Usual Pediatric Dose for Allergic Reaction
0.25 mg/kg/day or 8 mg/m2 body surface area in 2 to 3 divided doses, or by age as follows:
2 to 6 years: 2 mg orally two to three times a day, not to exceed 12 mg/day
7 to 14 years: 4 mg orally two to three times a day, not to exceed 16 mg/day
Usual Pediatric Dose for Allergic Rhinitis
0.25 mg/kg/day or 8 mg/m2 body surface area in 2 to 3 divided doses, or by age as follows:
2 to 6 years: 2 mg orally two to three times a day, not to exceed 12 mg/day
7 to 14 years: 4 mg orally two to three times a day, not to exceed 16 mg/day
Usual Pediatric Dose for Pruritus
0.25 mg/kg/day or 8 mg/m2 body surface area in 2 to 3 divided doses, or by age as follows:
2 to 6 years: 2 mg orally two to three times a day, not to exceed 12 mg/day
7 to 14 years: 4 mg orally two to three times a day, not to exceed 16 mg/day
Usual Pediatric Dose for Urticaria
0.25 mg/kg/day or 8 mg/m2 body surface area in 2 to 3 divided doses, or by age as follows:
2 to 6 years: 2 mg orally two to three times a day, not to exceed 12 mg/day
7 to 14 years: 4 mg orally two to three times a day, not to exceed 16 mg/day
Usual Pediatric Dose for Anorexia
> 13 years: 2 mg orally 4 times a day. May be increased gradually over a 3 week period to 8 mg 4 times a day. Maximum dose is 32 mg/day.
Usual Pediatric Dose for Migraine
4 mg orally two to three times a day
Renal Dose Adjustments
Data not available
Liver Dose Adjustments
The pharmacokinetics of cyproheptadine in patients with liver disease have not been studied. Since cyproheptadine is primarily metabolized by the liver, caution is advised when it is administered to patients with impaired hepatic function.
Precautions
Cyproheptadine should not be used in newborn or premature infants.
Dialysis
Data not available
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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