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Antiadrenergic agents, peripherally acting

What are Antiadrenergic agents, peripherally acting?

Alpha adrenoreceptor antagonists prevent the stimulation of alpha-adrenergic receptors at the nerve endings of the sympathetic nervous system. There are two types of alpha-adrenergic receptors, alpha 1 (on the vascular smooth muscle) and alpha 2 (on the vascular smooth muscle and sympathetic nerve terminals).

Alpha-adrenoreceptor antagonists are classed either as non-selective alpha adrenoreceptor antagonists, alpha1-selective antagonists, alpha2-selective antagonists and ergot derivatives.

The medicines used as cardiovascular agents are alpha1-selective antagonists. Alpha1-selective antagonists block the alpha adrenoreceptors on the vascular smooth muscle and widen the arteries, causing vasodilatation and a drop in blood pressure. These agents are used to treat hypertension.

Alpha1-receptor antagonists also cause relaxation of the smooth muscle of the bladder neck and prostate capsule. The longer acting alpha1 antagonists are used to treat urinary retention related to benign prostate hypertrophy.

List of Antiadrenergic agents, peripherally acting:

View by  Brand | Generic
Drug Name Reviews Avg. Ratings
Cardura XL (Pro)
Generic name: doxazosin
3 reviews
Cardura (Pro)
Generic name: doxazosin
6 reviews
Minipress (Pro)
Generic name: prazosin
14 reviews
Hytrin (Pro)
Generic name: terazosin
15 reviews
Uroxatral (Pro)
Generic name: alfuzosin
19 reviews
Flomax (Pro)
Generic name: tamsulosin
248 reviews
Rapaflo (Pro)
Generic name: silodosin
96 reviews
Jalyn (Pro)
Generic name: dutasteride / tamsulosin
19 reviews
Generic name: guanadrel
0 reviewsAdd rating
Generic name: mecamylamine
0 reviewsAdd rating
Ismelin (Pro)
Generic name: guanethidine
0 reviewsAdd rating
Vecamyl (Pro)
Generic name: mecamylamine
0 reviewsAdd rating
For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

See Also

Medical conditions associated with antiadrenergic agents, peripherally acting: