Skip to main content

Medications for Raynaud's Syndrome

Other names: Raynaud's Disease; Raynaud's Phenomenon

Raynaud's Syndrome is a condition in which cold temperatures or strong emotions cause blood vessel spasms that block blood flow to the fingers, toes, ears, and nose.

Drugs used to treat Raynaud's Syndrome

The medications listed below are related to or used in the treatment of this condition.

Filter
Drug name Rating Reviews Activity ? Rx/OTC Pregnancy CSA Alcohol
amlodipine Off-label 5.1 20 reviews for amlodipine to treat Raynaud's Syndrome
Rx C N X
Generic name:
amlodipine systemic
Drug class:
calcium channel blocking agents
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
nifedipine Off-label 7.7 44 reviews for nifedipine to treat Raynaud's Syndrome
Rx C N X
Generic name:
nifedipine systemic
Drug class:
calcium channel blocking agents
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
diltiazem Off-label 4.5 2 reviews for diltiazem to treat Raynaud's Syndrome
Rx C N X
Generic name:
diltiazem systemic
Drug class:
calcium channel blocking agents, group IV antiarrhythmics
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
Nitro-Bid 10 2 reviews for Nitro-Bid to treat Raynaud's Syndrome
Rx C N X
Generic name:
nitroglycerin systemic
Drug class:
antianginal agents, vasodilators
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
nitroglycerin 10 2 reviews for nitroglycerin to treat Raynaud's Syndrome
Rx C N X
Generic name:
nitroglycerin systemic
Brand name:
Nitro-Bid
Drug class:
antianginal agents, vasodilators
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
prazosin 9.5 2 reviews for prazosin to treat Raynaud's Syndrome
Rx C N X
Generic name:
prazosin systemic
Brand name:
Minipress
Drug class:
antiadrenergic agents, peripherally acting
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
felodipine 9.5 2 reviews for felodipine to treat Raynaud's Syndrome
Rx C N X
Generic name:
felodipine systemic
Drug class:
calcium channel blocking agents
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
trolamine salicylate Off-label 5.5 2 reviews for trolamine salicylate to treat Raynaud's Syndrome
OTC N N
Generic name:
trolamine salicylate topical
Brand names:
Arthricream, Asper-Flex, Myoflex
Drug class:
topical rubefacient
For consumers:
dosage, side effects
Off-label:
Yes
Cardura Rate Add review
Rx C N X
Generic name:
doxazosin systemic
Drug class:
antiadrenergic agents, peripherally acting, alpha-adrenoreceptor antagonists
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
doxazosin Rate Add review
Rx C N X
Generic name:
doxazosin systemic
Brand name:
Cardura
Drug class:
antiadrenergic agents, peripherally acting, alpha-adrenoreceptor antagonists
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
isoxsuprine 9.0 1 review for isoxsuprine to treat Raynaud's Syndrome
Rx C N
Generic name:
isoxsuprine systemic
Drug class:
peripheral vasodilators
For consumers:
interactions, side effects
For professionals:
Prescribing Information
Minipress Rate Add review
Rx C N X
Generic name:
prazosin systemic
Drug class:
antiadrenergic agents, peripherally acting
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Arthricream Off-label 1.0 1 review for Arthricream to treat Raynaud's Syndrome
OTC N N
Generic name:
trolamine salicylate topical
Drug class:
topical rubefacient
For consumers:
dosage, side effects
Off-label:
Yes
Sular 1.0 1 review for Sular to treat Raynaud's Syndrome
Rx C N X
Generic name:
nisoldipine systemic
Drug class:
calcium channel blocking agents
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Asper-Flex Off-label Rate Add review
OTC N N
Generic name:
trolamine salicylate topical
Drug class:
topical rubefacient
For consumers:
dosage, side effects
Off-label:
Yes
isradipine 5.0 1 review for isradipine to treat Raynaud's Syndrome
Rx C N X
Generic name:
isradipine systemic
Drug class:
calcium channel blocking agents
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Myoflex Off-label Rate Add review
OTC N N
Generic name:
trolamine salicylate topical
Drug class:
topical rubefacient
For consumers:
dosage, side effects
Off-label:
Yes
nisoldipine 5.5 2 reviews for nisoldipine to treat Raynaud's Syndrome
Rx C N X
Generic name:
nisoldipine systemic
Brand name:
Sular
Drug class:
calcium channel blocking agents
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information

Learn more about Raynaud's Syndrome

Care guides

Symptoms and treatments

Legend

Rating For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).
Activity Activity is based on recent site visitor activity relative to other medications in the list.
Rx Prescription only.
OTC Over-the-counter.
Rx/OTC Prescription or Over-the-counter.
Off-label This medication may not be approved by the FDA for the treatment of this condition.
EUA An Emergency Use Authorization (EUA) allows the FDA to authorize unapproved medical products or unapproved uses of approved medical products to be used in a declared public health emergency when there are no adequate, approved, and available alternatives.
Expanded Access Expanded Access is a potential pathway for a patient with a serious or immediately life-threatening disease or condition to gain access to an investigational medical product (drug, biologic, or medical device) for treatment outside of clinical trials when no comparable or satisfactory alternative therapy options are available.
Pregnancy Category
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act (CSA) Schedule
M The drug has multiple schedules. The schedule may depend on the exact dosage form or strength of the medication.
U CSA Schedule is unknown.
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.