Medications for Raynaud's Syndrome

Other names: Raynaud's Disease; Raynaud's Phenomenon

Raynaud's Syndrome is a condition in which cold temperatures or strong emotions cause blood vessel spasms that block blood flow to the fingers, toes, ears, and nose.

Drugs used to treat Raynaud's Syndrome

The following list of medications are in some way related to or used in the treatment of this condition.

Drug name	Rating	Reviews	Rx/OTC	Pregnancy	CSA	Alcohol
amlodipine	5.5	16 reviews	Rx	C	N
Generic name: amlodipine systemic Brand name: Norvasc Drug class: calcium channel blocking agents For consumers: dosage, interactions, side effects For professionals: AHFS DI Monograph, Prescribing Information

nifedipine	7.7	43 reviews	Rx	C	N
Generic name: nifedipine systemic Brand names: Adalat, Procardia Drug class: calcium channel blocking agents For consumers: dosage, interactions, side effects For professionals: AHFS DI Monograph, Prescribing Information

Norvasc	6.0	4 reviews	Rx	C	N
Generic name: amlodipine systemic Drug class: calcium channel blocking agents For consumers: dosage, interactions, side effects For professionals: Prescribing Information

Adalat	8.3	7 reviews	Rx	C	N
Generic name: nifedipine systemic Drug class: calcium channel blocking agents For consumers: dosage, interactions, side effects

diltiazem Off-label	8.0	1 review	Rx	C	N
Generic name: diltiazem systemic Drug class: calcium channel blocking agents, group IV antiarrhythmics For consumers: dosage, interactions, side effects For professionals: AHFS DI Monograph, Prescribing Information Off-label: Yes

Nitro-Bid	10	2 reviews	Rx	C	N	X
Generic name: nitroglycerin systemic Drug class: antianginal agents, vasodilators For consumers: dosage, interactions, side effects For professionals: Prescribing Information

Procardia	7.7	6 reviews	Rx	C	N
Generic name: nifedipine systemic Drug class: calcium channel blocking agents For consumers: dosage, interactions, side effects For professionals: Prescribing Information

nitroglycerin	10	2 reviews	Rx	C	N	X
Generic name: nitroglycerin systemic Brand name: Nitro-Bid Drug class: antianginal agents, vasodilators For consumers: dosage, interactions, side effects For professionals: AHFS DI Monograph, Prescribing Information

felodipine	9.5	2 reviews	Rx	C	N
Generic name: felodipine systemic Drug class: calcium channel blocking agents For consumers: dosage, interactions, side effects For professionals: AHFS DI Monograph, Prescribing Information

prazosin	9.5	2 reviews	Rx	C	N	X
Generic name: prazosin systemic Brand name: Minipress Drug class: antiadrenergic agents, peripherally acting For consumers: dosage, interactions, side effects For professionals: AHFS DI Monograph

trolamine salicylate Off-label	5.5	2 reviews	OTC	N	N
Generic name: trolamine salicylate topical Brand names: Arthricream, Asper-Flex, Myoflex Drug class: topical rubefacient For consumers: dosage, side effects Off-label: Yes

Cardura	Rate	Add review	Rx	C	N	X
Generic name: doxazosin systemic Drug class: antiadrenergic agents, peripherally acting, alpha-adrenoreceptor antagonists For consumers: dosage, interactions, side effects For professionals: Prescribing Information

Minipress	Rate	Add review	Rx	C	N	X
Generic name: prazosin systemic Drug class: antiadrenergic agents, peripherally acting For consumers: dosage, interactions, side effects For professionals: Prescribing Information

doxazosin	Rate	Add review	Rx	C	N	X
Generic name: doxazosin systemic Brand name: Cardura Drug class: antiadrenergic agents, peripherally acting, alpha-adrenoreceptor antagonists For consumers: dosage, interactions, side effects For professionals: AHFS DI Monograph, Prescribing Information

Arthricream Off-label	1.0	1 review	OTC	N	N
Generic name: trolamine salicylate topical Drug class: topical rubefacient For consumers: dosage, side effects Off-label: Yes

isoxsuprine	9.0	1 review	Rx	C	N
Generic name: isoxsuprine systemic Drug class: peripheral vasodilators For consumers: interactions, side effects For professionals: Prescribing Information

Sular	1.0	1 review	Rx	C	N
Generic name: nisoldipine systemic Drug class: calcium channel blocking agents For consumers: dosage, interactions, side effects For professionals: Prescribing Information

Asper-Flex Off-label	Rate	Add review	OTC	N	N
Generic name: trolamine salicylate topical Drug class: topical rubefacient For consumers: dosage, side effects Off-label: Yes

isradipine	5.0	1 review	Rx	C	N
Generic name: isradipine systemic Drug class: calcium channel blocking agents For consumers: dosage, interactions, side effects For professionals: AHFS DI Monograph, Prescribing Information

Myoflex Off-label	Rate	Add review	OTC	N	N
Generic name: trolamine salicylate topical Drug class: topical rubefacient For consumers: dosage, side effects Off-label: Yes

nisoldipine	5.5	2 reviews	Rx	C	N
Generic name: nisoldipine systemic Brand name: Sular Drug class: calcium channel blocking agents For consumers: dosage, interactions, side effects For professionals: AHFS DI Monograph, Prescribing Information

Learn more about Raynaud's Syndrome

Care guides

Symptoms and treatments

Raynaud's Phenomenon

Legend

Rating	For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).
Activity	Activity is based on recent site visitor activity relative to other medications in the list.
Rx	Prescription only.
OTC	Over-the-counter.
Rx/OTC	Prescription or Over-the-counter.
Off-label	This medication may not be approved by the FDA for the treatment of this condition.
EUA	An Emergency Use Authorization (EUA) allows the FDA to authorize unapproved medical products or unapproved uses of approved medical products to be used in a declared public health emergency when there are no adequate, approved, and available alternatives.

Pregnancy Category
A	Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B	Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C	Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D	There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X	Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N	FDA has not classified the drug.

Controlled Substances Act (CSA) Schedule
M	The drug has multiple schedules. The schedule may depend on the exact dosage form or strength of the medication.
U	CSA Schedule is unknown.
N	Is not subject to the Controlled Substances Act.
1	Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2	Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3	Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4	Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5	Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.

Alcohol
X	Interacts with Alcohol.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer