Antianginal agents is a term used to describe a wide variety of medicines that are used in the management of angina. Angina is a heart condition characterized by a narrowing of the coronary arteries (the arteries of the heart). Chest pain is its main symptom.
Examples of antianginal agents include:
Nitrates (eg, isosorbide dinitrate, isosorbide mononitrate, nitroglycerin). These relax smooth muscle within the blood vessels, widening them and making it easier for blood and oxygen to reach the heart
Calcium antagonists (eg, diltiazem, nifedipine, nimodipine, verapamil). These inhibit calcium transfer into cells thereby inhibiting contraction of vascular smooth muscle
Beta blockers (eg, atenolol, pindolol, propranolol, metoprolol). These slow the heart, reducing how hard it has to work
Ranolazine. The exact way it exerts its antianginal effect is not known but may be through inhibition of ion channels during cardiac repolarization.
Subscribe to receive email notifications whenever new articles are published.
Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Data sources include Micromedex® (updated Oct 2nd, 2017), Cerner Multum™ (updated Oct 4th, 2017), Wolters Kluwer™ (updated Oct 2nd, 2017) and others. To view content sources and attributions, please refer to our editorial policy.