Nitroglycerin User Reviews & Ratings
Brand names: Nitrostat, Nitro-Bid, Rectiv, Nitrolingual Pumpspray, Nitro-Dur, Nitrostat Tablets, Minitran, Nitro-Time NitroMist Deponit Nitro TD Patch-A GoNitro …show all brand names
Nitroglycerin has an average rating of 7.5 out of 10 from a total of 54 reviews on Drugs.com. 64% of reviewers reported a positive experience, while 13% reported a negative experience.
Condition | Avg. Rating | Reviews | Compare |
---|---|---|---|
Anal Fissure and Fistula | 38 reviews for Anal Fissure and Fistula | 1 medications | |
Angina | 8 reviews for Angina | 127 medications | |
Heart Attack | 2 reviews for Heart Attack | 126 medications | |
High Blood Pressure | 2 reviews for High Blood Pressure | 275 medications | |
Raynaud's Syndrome | 2 reviews for Raynaud's Syndrome | 29 medications | |
Angina Pectoris Prophylaxis | 1 reviews for Angina Pectoris Prophylaxis | 136 medications | |
Heart Failure | 1 reviews for Heart Failure | 128 medications |
Reviews for Nitroglycerin
- Jus...
- Taken for less than 1 month
- February 13, 2020
Rectiv (nitroglycerin) for Anal Fissure and Fistula "Dealt with anal fissures for multiple years. Lived in 24/7 anxiety. Spent countless hours researching the internet for solutions. Felt like I was becoming as knowledgeable as a colorectal surgeon. The first couple of times I tried Rectiv, the headaches were insane. Very intense. To the point I quit taking it. I started up again and dealt with it, and after a couple of days, the headaches went away—as did my symptoms. The 0.4% nitro solution can be made into a 0.2% compound at a specialty pharmacy—which will ease the headaches. (And only cost $17!) Bottom line is: the stuff works."
- vig...
- January 18, 2009
Nitro-Bid (nitroglycerin) for Raynaud's Syndrome "I am 60 years old and have had Raynaud's syndrome for 10 years. The first episode was when I was diagnosed, when I looked like I would lose a finger from severe frostbite. However, a wonderful surgeon told me to try Nitro-Bid cream on that finger for 7 days, before resorting to removing the finger. It was miraculous as within those 7 days my skin started to renew itself and the sheer pain of it all was gone within 3 days. He saved my index finger on my left hand, and I was extremely grateful."
Frequently asked questions
- How do you take GoNitro to treat an angina attack (chest pain)?
- What is the shelf life of nitroglycerin tablets?
- Bil...
- Taken for less than 1 month
- January 12, 2020
Rectiv (nitroglycerin) for Anal Fissure and Fistula "Suffered excruciating butt pain on and off over the last year. The anticipation of another bowel movement caused great anxiety. Tried diet change and fiber supplements. Started applying Rectiv three days ago. On my fourth day. All pain has subsided. Very slight “tingle” in my head when initially used each time. Wouldn’t consider it a headache, but more of an indication the medication was taking effect. Dr. prescribed the day before I was leaving for vacation to the Keys. Writing this on the beach - pain-free."
- Ame...
- May 31, 2017
Rectiv (nitroglycerin) for Anal Fissure and Fistula "I struggled with intense pain and bleeding due to a fissure for several months. Assuming it was hemorrhoids, I tried multiple over-the-counter medicines, but nothing worked. My OB/GYN was the one who realized it was a fissure and prescribed Rectiv. The headaches were rough at first, and I almost quit using the ointment because of them. I'm so glad I didn't, though. Within one week, the headaches were gone, and my fissure symptoms were calming down. By week two, I was totally back to normal-no pain, no bleeding. I continued using it for another week, just to be sure I was completely healed. I've been off it for two weeks now, and I'm still symptom-free. I can't sing the praises of this medicine enough!!"
Are you taking this medicine?
Your review helps others make informed decisions.- sca...
- Taken for less than 1 month
- January 27, 2021
Rectiv (nitroglycerin) for Anal Fissure and Fistula "This medicine sat on my shelf for over 6 months - I was so afraid of the 'worst headache ever' described in many posts. I finally became desperate enough to use it and am on the 5th day now. Please don't be afraid to try this. It has absolutely helped the fissure. No pain or blood the last 3 days (after over 1 year of pain and bleeding). Every application I do get an unpleasant pressure sensation in my head immediately (which is creepy), but it does go away in an hour. Only once was it a full-on headache and I think I used too much of the product. But not even so bad of a headache that I took Tylenol or Advil for it. Be very careful to only apply the 1 inch amount. The product does burn my skin a bit - I suspect the PEG or lanolin ingredients. If I ever need it again, I would ask about a compounding pharmacy preparing a hypo-allergenic version. I am F, 5'7 weight 120. I am usually very sensitive to medicines and often choose pediatric doses of products."
- Rel...
- Taken for less than 1 month
- September 4, 2018
Rectiv (nitroglycerin) for Anal Fissure and Fistula "I suffered for over a year with an anal fissure that was so painful I’d lay in the bath 3-4 times a day to get relief. It was also infected and was leaking a horrible, smelly, clear discharge. I finally went to the doctor and had it checked out. He prescribed this to see if it would work, and within a couple weeks I was healed and had 0 pain. The headaches only last a week or less from the first use. This stuff is amazing, and I can’t praise it enough. I thought I was gonna have to deal with the excruciating pain forever."
- Cos...
- Taken for less than 1 month
- December 6, 2021
Rectiv (nitroglycerin) for Anal Fissure and Fistula "I have been struggling with an anal fissure for about 3 months. Tried prescription-strength lidocaine, which didn’t help at all. Today, my doctor prescribed Rectiv, and I have to say it really, really works to alleviate the pain in my butt. That’s the good news. The bad news is that within literally 5 minutes of applying an inch of Rectiv, I am experiencing one of the worst headaches I have ever had. It is excruciating to even look at this screen. Took over-the-counter headache meds, but after three hours, still no relief from the headache. It’s almost worse than the pain from the fissure. Almost, but not quite. The other problem with this medication is my insurance will only cover 20% of the cost. That means I paid $499.00 out of pocket for one tube of this ointment! This is unacceptable. Drug manufacturers and insurance companies have got to get together and work this out so average people can afford this care. If I were on a fixed income, there would be no way to get access."
- Bea...
- Taken for less than 1 month
- August 24, 2015
Rectiv (nitroglycerin) for Anal Fissure and Fistula "I developed anal fissures after using Invokamet and Invokana. My GI Dr. prescribed Rectiv to heal them. It worked! However, I got an instant migraine each time. You cannot take aspirin, so I took my migraine medicine - Fiorcet. It took about two weeks to heal. A real godsend! Only downfall was the cost - $525.00 per tube. Insurance covered it, thankfully!"
- Ugh...
- Taken for less than 1 month
- April 18, 2020
Rectiv (nitroglycerin) for Anal Fissure and Fistula "Worst headache ever, instantly after application of Rectiv. It does alleviate the rectal hell I've experienced. I am miserable, and I'm just praying this heals. I DON'T KNOW HOW MUCH LONGER I CAN DO THE FISSURE OR THIS MEDICATION."
- Pri...
- February 24, 2016
For Angina "I have had heart disease for many years and always have a bottle (tiny!) of sublingual nitros in my pocket. When I feel chest pain, one under the tongue and the pain goes away, in my case, every time. The nitro works very quickly to dilate your blood vessels, allowing more blood and oxygen to get to your heart muscle. Ask your doctor how to proceed should one pill not relieve the pain. Sublinguals have a limited life, once the bottle is opened the first time, about 3-6 months. If you find yourself using all the pills within that time (25 tiny tablets, typically), then they are best. If you only need it occasionally, get the pump spray as it has a much longer life. It is, however, more expensive."
- Fis...
- Taken for less than 1 month
- June 10, 2021
Rectiv (nitroglycerin) for Anal Fissure and Fistula "My advice is to take 2 Tylenol Extra Strength or ibuprofen 15 min before applying nitroglycerin ointment to the anal area. This will help with the headache that you will get. Use a small dab, like on a cotton swab, and apply to the outside of the anus. Inside application and you're asking for a tear-your-head-apart headache. Do this at night when you are home for the day. I wouldn't advise using this before or during the workday, because you can experience a back-of-the-head migraine for around 1-2 hours. And you more than likely won't make it through the workday."
- JLa...
- May 10, 2021
Rectiv (nitroglycerin) for Anal Fissure and Fistula "After countless visits to the doctor, an emergency room physician figured out I had a fissure and not hemorrhoids. For the side effect of headache? Take some Advil and drink some water, and it doesn’t even hurt anymore. This medication works. In the three days I’ve been using it, my pain has reduced substantially, and my bleeding has stopped."
- Jul...
- March 23, 2018
Rectiv (nitroglycerin) for Anal Fissure and Fistula "This is a fantastic medication. I was trying everything over the counter, and nothing really helped till my doctor put me on Rectiv. I thank God for this medication and my doctor for prescribing it. Within 3 days of use, the pain subsided, and I felt a major difference. I'm back to my old self again."
- APa...
- Taken for less than 1 month
- April 28, 2020
Rectiv (nitroglycerin) for Anal Fissure and Fistula "I've been using this ointment for three days now and just started noticing that bowel movements are less painful. The headache side effect is a real thing, but for me, it isn't strong and only lasts for about 20-30 minutes. It does happen every single time though, and it's almost instant. My insurance did cover this, but I still paid $80.00 for one tube."
- RNa...
- Taken for less than 1 month
- August 15, 2019
For Anal Fissure and Fistula "I'm a GI nurse, and I was in so much pain. Tried to self-manage, thinking it was only hemorrhoids, but in fact, I had a good-sized fissure and was prescribed this. Yes, it is expensive, I was almost tempted to leave it at the pharmacy, but I decided that I needed to just take care of the issue. First dose was scary, I had palpitations, I was sweating, and I instantly got a headache. For my second dose, I used a little less (pea-sized), and it was okay. Yes, there is a headache, but it went away within an hour. I’m on day 3, and I’m already seeing an improvement. I don’t think I would use it for 3 weeks like I was prescribed, but yes, meds work. FYI, use gloves when handling this med."
- AL5...
- Taken for less than 1 month
- July 22, 2020
For Anal Fissure and Fistula "This part of the leaflet my hospital NHS gave me. About 60-70% of people with a chronic anal fissure are cured with a 6-8 week course of GTN. Therefore, the chance of a cure by using GTN is better than with the supportive method alone. You should rub a pea-sized amount of the ointment into the skin around the rim of the anus 2-3 times a day. Do not push it inside the anus. If you do, it will be absorbed into the bloodstream 3, and you are more likely to get side effects, such as a headache. It is important that you complete the full course of treatment, as it may take 6-8 weeks of treatment for the fissure to heal fully. However, symptoms such as pain may ease quickly. Hope it helps, guys and girls."
- Ard...
- March 27, 2012
For Angina "This spray is very effective in eradicating nocturnal angina pain and as a precursor to physical exercise, thereby inhibiting pain. Very effective pain reliever in a convenient delivery system, fantastic!"
- vir...
- Taken for 10 years or more
- April 18, 2020
Nitrolingual Pumpspray (nitroglycerin) for Angina "I have used Nitrolingual spray for about 10 years now and hate going out anywhere without it. Just a note though. On the bottle, it says '200 doses'... absolutely no way. Further, about 8 mm height of the liquid is left in each bottle and not able to be dispensed. Surely a better designed bottle/dispenser is not that hard to come up with. That's probably over 300 mm in depth wasted over the 10 years I have used the product. Plus, I will be out walking and need the spray. Seeing there seems to be plenty in the bottle, I take it with me. Every time I get caught and am not able to spray any of the product."
- tnu...
- March 10, 2014
Rectiv (nitroglycerin) for Anal Fissure and Fistula "I'm on day 2 of this product, and I 'feel' a drastic difference. I am forever grateful to my doctor for prescribing this. Three years ago, I had the same issue, and I suffered for three months with excruciating pain during my bowel movement to the point I added to my misery by holding it for up to a week at a time to suffer from as few painful bowel motions as possible, all because I was too embarrassed to show this problem to my doctor. Never again, and I really thank the pharmacist for the coupon to bring my cost down to $40. There is a mild side effect, I didn't have a headache, more so painless throbbing in my head for the first 1-2 hours after application. I was still able to function and get through my clinicals without feeling faint or ill."
- for...
- September 26, 2013
Nitro-Bid (nitroglycerin) for Heart Attack "My dad is in the last stages of congestive heart failure. This mainly means he still functions as much as he can but will continue to degrade. His heart seemed to hurt very consistently. His Dr. gave him Nitro-Bid. He applied it as a cream to the chest area 1 or 2 times a day. After less than 2 months, he was only using it as needed, which was perhaps 1-2 times a month. A very good, fast-acting addition to comfort care."
- Mfi...
- January 23, 2020
Rectiv (nitroglycerin) for Anal Fissure and Fistula "I have never had such a severe headache in my life. Made the mistake of using before bed. Headache kept me up all night into the morning, finally had to take caffeine pills to try to constrict the blood vessels in my head. I will NEVER use this again. Rather have pain in my butt than feel like my head is being ripped apart."
- Cba...
- April 25, 2019
Rectiv (nitroglycerin) for Anal Fissure and Fistula "Tried this cream (Rectiv) once, and I had a severe headache. Not knowing it was the cause, I tried the second dose, and I had an excruciating headache that not even painkillers could take away. Didn’t take it again..."
- MKa...
- Taken for 1 to 6 months
- August 20, 2018
For Anal Fissure and Fistula "I have had a fissure for a month now. Thinking it was a hemorrhoid, I tried to treat it myself. Unfortunately for me, the pain got worse one day and was so bad I had to go to the ER. Just so they could prescribe me some kind of painkiller... which they didn't do. Fast forward two weeks, and I have an appointment with a specialist. He applies the cream for inspection, and just that small amount for the digital exam was enough to give me almost instant pain relief. Instant as in a few minutes later, the pain was bearable enough where I could sit and sleep. If you are having symptoms of hemorrhoids, just go in and get your body checked out. I was in high school when I got my first one and did not have any kind of rectal exam due to embarrassment until I was 25. Don't be me. Get an exam and get relief, and get it fixed. Just don't go to a crappy ER like I did."
- pis...
- January 23, 2020
For High Blood Pressure "I went in for my Medicare 1st physical for the insurance. I liked the doctor. My blood pressure was high, 191/113, which was about average for me. In fact, just days before my appointment it was 234/117. Anyway, he wanted me to go to the hospital. I said no and signed a paper so he would not be responsible. Fine. He then proceeded to have his assistant put a nitro bid 25 on my chest and sent me home with a prescription of clonidine. By the time I arrived home, my head was screaming off my shoulders. I was having chest pressure, weak, and could not function. I spent the next 3 days in bed. He said to keep it on for 6 hours. I was done at 5. My blood pressure went to 237/120. As far as the clonidine, let's see, it causes liver and kidney failure, makes you weak, fatigued, can't drive, headaches, causes you to lose your hair, and makes you nauseated. So how are these things helping my blood pressure? Oh, by the way, I felt great before going to the doctor."
More about nitroglycerin
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- During pregnancy
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- Drug class: antianginal agents
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Patient resources
- Nitroglycerin oral/sublingual drug information
- Nitroglycerin rectal
- Nitroglycerin topical
- Nitroglycerin transdermal
- Nitroglycerin (Intravenous) (Advanced Reading)
Other brands
Nitrostat, Nitro-Bid, Nitrolingual Pumpspray, Rectiv, ... +10 more
Professional resources
- Nitroglycerin monograph
- Nitroglycerin (Topical) (AHFS Monograph)
- Nitroglycerin Dextrose (FDA)
- Nitroglycerin ER (FDA)
- Nitroglycerin Injection (FDA)
Other brands
Nitrostat, Nitro-Bid, Nitrolingual Pumpspray, Rectiv, ... +5 more
Nitrostat (nitroglycerin) for Angina "My cardiologist recommended this drug to relieve shortness of breath at night due to atrial fibrillation. The sublingual 0.4 mg tablet gives a slight burning sensation under the tongue, which is not uncomfortable. A slight headache was felt on the forehead but was of short duration. The immediate dilation of the blood vessels achieves relief within one minute. Very positive results."