Skip to main content

User Reviews for Isosorbide mononitrate

Isosorbide mononitrate has an average rating of 5.0 out of 10 from a total of 81 ratings on Drugs.com. 43% of reviewers reported a positive experience, while 48% reported a negative experience.

Condition Avg. Rating Reviews Compare
Angina  
4.1
48 reviews 132 medications
Angina Pectoris Prophylaxis  
6.0
22 reviews 132 medications
Heart Failure  
6.7
9 reviews 124 medications
Esophageal Spasm  Off-label
5.5
2 reviews 8 medications
Summary of Isosorbide mononitrate reviews 5.0 81 reviews

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published.

Reviews for Isosorbide mononitrate

nattlee · June 14, 2010

Imdur (isosorbide mononitrate) for Angina Pectoris Prophylaxis: “I was put on this medication along with a very low dose ACE inhibitor that controls my blood pressure. The Imdur ER is being used to alleviate my chest pain and it has done so completely. I have not have one single flair up at all since starting it! The only down fall is the headache that I have had. I am going to call my cardiologist today to see if I can take anything for that. I still give it a 10 even with the headache because the chest pain was worse than the headache!”

10 / 10
Was this helpful?YesNo
Granny · Taken for 6 months to 1 year · July 20, 2019

Imdur (isosorbide mononitrate) for Heart Failure: “Dr started me on Imdur for angina/heart failure-after about 1 week, shortness of breath gone and I have no chest pain. I couldn't even turn over in bed without getting short of breath no side effects all-still taking after 6mths & feel great.”

10 / 10
Was this helpful?YesNo
StanLee · Taken for less than 1 month · July 10, 2019

For Angina: “I was prescribed these tablets -isosorbide 40mg Modified-Release tablets to be taken 1 each morning. 8-10 hours after taking my first tablet I had to go to bed with a terrible headache starting at the back of my head, into my neck. The pain spread across my shoulders and into my arms. It felt like severe arthritis, and couldn't get relief no matter how I tried. I can't remember ever feeling pain like it, and got very little sleep that night. Nothing could persuade me to take another one of these tablets. Dreadful medication.”

1 / 10
Was this helpful?YesNo
Jackson · Taken for less than 1 month · July 15, 2019

Imdur (isosorbide mononitrate) for Angina: “I was taking 30mg and the doc increased the Imdur to 60 mg now I have a headache, can’t sleep feel like everything is moving or spinning , and pain in my neck and my low back feels disconnected when in bed and all I want to do is vomit, it has been 2 days since the increase”

7 / 10
Was this helpful?YesNo
mackie NYC NY · Taken for 2 to 5 years · June 11, 2020

For Angina: “Dr, put me on Isosorbide Mononitrate 60mg twice day, (did start with 30 twice day) I am 86 yrs have severe COPD. After reading 3 pages of reviews I am shocked at what other folks have had in side effects. I have had nothing in side effects that I am aware of and tightness in chest is now very rare. Have outstanding doctor for over 15 yrs. He gave me his cell phone years ago. He has made 2 house calls this year. I am really blessed. Been on med since Oct 2017.”

9 / 10
Was this helpful?YesNo
nana903 · June 22, 2009

For Esophageal Spasm: “This medicine has saved my life after months of having chest pains everyday. I became weak and felt like I had nothing to live for. The doctors ruled out my heart and ruled I had esophageal spasms. They had tried other medications that did not work. My gastroenterologist gave me the time released IMDUR. IT HAS GIVEN ME MY LIFE BACK IN JUST OVER A WEEK. I HAVE MY ENERGY BACK AND I AM HAPPY TO SAY NO CHEST PAIN. THE ONLY SIDE EFFECT IS A HEADACHE BUT I CAN HANDLE THAT WITH TYLENOL. I HAVE MY LIFE BACK. THANK YOU SO MUCH.”

10 / 10
Was this helpful?YesNo
Mwk1 · Taken for less than 1 month · September 8, 2020

For Angina: “Taken isosorbide mononitrate 30mg for 4 days. Had side effect of the most horrendous headache and neck pain and had to be sent home from work as pain was so bad. Lasted for about 8 hours. Not taking it tomorrow and will speak to Dr. Really confused about whether to continue with it. I expected a headache but this is ridiculous.”

Was this helpful?YesNo
Tosca · Taken for 5 to 10 years · January 22, 2020

For Angina: “Been taking extended release for five years. I had a pretty gnarly headache the first few days, was told to expect this, so that made it more tolerable. I have have had no side effects of note since then. Seems to help, although I have had angina occasionally while on it. My assumption here is I probably would have more angina without it.”

9 / 10
Was this helpful?YesNo
marklvnv · July 4, 2011

For Angina Pectoris Prophylaxis: “My doctor prescribed this medicine due to on-going chest pain. I have now been taking it for 1 week and have a headache everyday. Nothing seems to help stop them. I have taken aspirin, Tylenol and even acetaminophen with codeine for relief and so far none have worked. The headache is constant throughout the day and is throbbing and causes dizziness. The good side is the chest pain has gone away. I'm considering stopping this medicine as the headaches are pretty bad.”

7 / 10
Was this helpful?YesNo
Betboop · June 7, 2015

For Angina Pectoris Prophylaxis: “I have been on this med for a couple months and I must say I feel sooooo much better! I have been fortunate in that I never had the headaches as have been reported in the reviews! My doctor just increased dose to 60 mg which has really helped me with my activity - no more shortness of breathe or pain! I have Angina and this med has helped big time! I have my quality of life back!”

10 / 10
Was this helpful?YesNo
Sonny Beach · November 3, 2015

Imdur (isosorbide mononitrate) for Angina Pectoris Prophylaxis: “I had chest pain and palpitations. Was prescribed Imdur and took 1 tablet. That was the worst 3 days of my life. I prefer the angina to the "cure." Caused nausea, vomiting, intense pain (felt like my body was made of broken glass), every sound went right thru me, and every noise was excruciating. Never again.”

1 / 10
Was this helpful?YesNo
Sue · Taken for 6 months to 1 year · September 3, 2019

For Angina Pectoris Prophylaxis: “Jackson. My Dr put me on 30 mg and I had a killer headache all night so I wasn't going to take again but broke the tablet in half and took it. I still had a small headache. I suggest slowly increasing isosorbide until your body adjusts to it and then continue increasing until you reach the desired dose the dr wants you on. I told my cardiologist and he said that was ok..just a suggestion - you probably should check with your Doctor and see what they think.”

Was this helpful?YesNo
karlab65 · Taken for 2 to 5 years · January 18, 2021

Imdur (isosorbide mononitrate) for Heart Failure: “I’ve been taking Imdur for several years for angina, blood pressure and other conditions and I have never felt better. I can breathe again, no chest pains, and I can do things with my family again. After being on blood thinners over 20 years, this has been a godsend!”

10 / 10
Was this helpful?YesNo
Cavalinesman · Taken for 1 to 6 months · March 2, 2013

For Angina Pectoris Prophylaxis: “I have had great results with this medicine. I've been taking this for several months. The headaches have all but gone. "Guess I'm getting used to them". You need to hang in there with the headaches. The benefits are worth it.”

10 / 10
Was this helpful?YesNo
savemyheart · January 24, 2015

For Heart Failure: “I was exhausted and constantly gasping for breath. My cardiologist put me on isosorbide mononitrate, one pill a day. The difference was astounding. I no longer was gasping for breath and no longer had to take naps. The pill would wear off during the night so the doctor recently changed me to two/day. Am experiencing some pretty severe headaches and dizziness when get up to fast. Doctor had told me I would experience headaches but they would go away eventually.”

9 / 10
Was this helpful?YesNo
Hud · Taken for less than 1 month · June 26, 2019

For Angina: “I was prescribed this drug isosorbide mononitrate after going to hospital with angina. I was sick of using GTN spray, as it gave me sore throats & headaches. Only took these tablets 3x30 mg doses over 3 days & had to have a week off work. The side effects were dizziness, couldn't open my eyes or see properly, wasn't sure what I was doing, tired all the time - worst thing I've ever taken. Back to the spray & aspirin now. Rather have a few minutes angina ,than all the side effects of Carmil (UK brand of isosorbide). Never again. Just hope my appointment to have a stent fitted arrives soon.Been waiting since March.......”

1 / 10
Was this helpful?YesNo
Shepherdess · Taken for less than 1 month · February 20, 2018

For Angina: “I’ve got Prinzmetal Angina and my doctor put me on this medication after a particularly bad attack. I am already taking Amlodipine and GTN when required. The headache and neck ache from this medication has been severe. I can do nothing else but lay flat in a darkened room. No painkiller relieves it. If you are unlucky enough to get these side effects, they are horrendous. I persisted with it for a week, but it was disabling.”

Was this helpful?YesNo
Tr · Taken for less than 1 month · October 18, 2020

For Angina: “I was prescribed this medicine for high blood pressure and Rayauds. The first day I developed a headache. I took two aspirins which helped somewhat. I had to immediately lay down and rest. I thought the symptoms would get better so I took the meds the following day. The headache got worse followed by neck pain. I also felt nausea, chills, and became fatigue. I vomited and felt sick to my stomach. I’m usually a tough person and have a high tolerance but this medicine made me feel awful ! I was literally on bed rest the entire day and didn’t have an appetite. Smells would make me nauseous! I would never ever take this medicine again or recommend it to anyone!”

1 / 10
Was this helpful?YesNo
Yikes · Taken for less than 1 month · December 4, 2020

For Angina: “Isosorbide Mononitrate 10mg twice a day was prescribed by hospital doctor for possible angina and I have never felt so ill! Taken for 2 days but never again! It did stop my brief chest pains but I've had the worst ever headache for the whole time even waking me up in the night and which painkillers won't touch, also hurts down my neck and side of my face and making me feel sick. Just horrendous. Phoned GP who is changing them for beta blockers as fewer side affects.”

Was this helpful?YesNo
Sally66 · February 1, 2016

Imdur (isosorbide mononitrate) for Angina Pectoris Prophylaxis: “In bed 24 hours severe pain head to toe blurred vision vomiting light sensitive extreme this all happened on the day that I took imdur - I'm taking 30 milligrams the next day I was in bed till about 2 I felt 75% better did not take imdur called the doctor and told them what was going on would not recommend this medication to my worst enemy”

1 / 10
Was this helpful?YesNo
Babs · Taken for less than 1 month · June 11, 2019

For Angina: “Started on Isosorbide mononitrate 30mg yesterday. Have had angina, SOB (shortness of breath), right hand and arm icy cold, since quad by-pass in 2017. Immediately after taking first dose felt "yukky", had the headache, dizzy, very tired, took an Ibuprofen and sat in recliner for about 2 hours, then felt much better and was able to walk in my yard with no chest pain (first since surgery)!. My right hand is warm! This morning took med then went back to bed for an hour. Slight headache right now. Will take Ibuprofen again. Still no chest pain or SOB. Right hand was cold, but is now warm again! I pray this continues.”

8 / 10
Was this helpful?YesNo
Mom · Taken for 1 to 6 months · August 4, 2018

For Angina: “My daughter was put on this for her resistant high blood pressure. It does the job of lowering her pressure very well, but it makes her heart beat erratically and makes her feel terrible all of the time. Severe headaches, a weak, heavy feeling, nausea, dizziness and breathlessness. It is really a tough drug to take. We had to stop the extended release and go with the normal one that only lasts a few hours just to give her some relief. Once she gets more used to it we might go back to ext. release. But in the meantime, its completely debilitating.”

5 / 10
Was this helpful?YesNo
Tahoe84ves · September 13, 2017

For Angina: “The headaches caused by this medication is worse than the condition it is supposed to treat. The pain goes on for at least 24 hours..it is debilitating and cannot be treated with Tylenol or cool compresses...avoid this med at all costs!”

Was this helpful?YesNo
Sandinnalee1 · Taken for less than 1 month · November 3, 2017

For Angina: “I've been on it 8 days. The dosage is 30 mg. I'm having stiff neck. The most terrible headache. It is for Angina. It is helping the chest pain. They say after a few weeks headaches will subside. I sure hope so.”

2 / 10
Was this helpful?YesNo
NCDavid · February 19, 2017

Imdur (isosorbide mononitrate) for Angina Pectoris Prophylaxis: “Took half dose, 15 mg, and spent two days feeling terrible. It caused chest and back pain, shortness of breath, confusion, dizziness, anxiety, and a general really sick feeling. It did relieve angina but it was not worth the side effects. Really bad medicine.”

1 / 10
Was this helpful?YesNo

This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.