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User Reviews for Isosorbide mononitrate

Isosorbide mononitrate has an average rating of 5.1 out of 10 from a total of 61 ratings on 45% of those users who reviewed Isosorbide mononitrate reported a positive effect, while 45% reported a negative effect.

Condition Avg. Rating Reviews Compare
33 reviews 130 medications
Angina Pectoris Prophylaxis  
19 reviews 131 medications
Heart Failure  
7 reviews 123 medications
Esophageal Spasm  Off-label
2 reviews 8 medications
Summary of Isosorbide mononitrate reviews 5.1 61 reviews

Reviews may be moderated or edited before publication to correct grammar and spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest in the medication will not be published. As reviews and ratings are subjective and self-reported, this information should not be used as the basis for any statistical analysis or scientific studies.

Reviews for Isosorbide mononitrate

karlab65 · Taken for 2 to 5 years January 18, 2021

Imdur (isosorbide mononitrate) for Heart Failure: “I’ve been taking Imdur for several years for angina, blood pressure and other conditions and I have never felt better. I can breathe again, no chest pains, and I can do things with my family again. After being on blood thinners over 20 years, this has been a godsend!”

10 / 10
Yikes · Taken for less than 1 month December 4, 2020

For Angina: “Isosorbide Mononitrate 10mg twice a day was prescribed by hospital doctor for possible angina and I have never felt so ill! Taken for 2 days but never again! It did stop my brief chest pains but I've had the worst ever headache for the whole time even waking me up in the night and which painkillers won't touch, also hurts down my neck and side of my face and making me feel sick. Just horrendous. Phoned GP who is changing them for beta blockers as fewer side affects.”

Tr · Taken for less than 1 month October 18, 2020

For Angina: “I was prescribed this medicine for high blood pressure and Rayauds. The first day I developed a headache. I took two aspirins which helped somewhat. I had to immediately lay down and rest. I thought the symptoms would get better so I took the meds the following day. The headache got worse followed by neck pain. I also felt nausea, chills, and became fatigue. I vomited and felt sick to my stomach. I’m usually a tough person and have a high tolerance but this medicine made me feel awful ! I was literally on bed rest the entire day and didn’t have an appetite. Smells would make me nauseous! I would never ever take this medicine again or recommend it to anyone!”

1 / 10
nattlee June 14, 2010

Imdur (isosorbide mononitrate) for Angina Pectoris Prophylaxis: “I was put on this medication along with a very low dose ACE inhibitor that controls my blood pressure. The Imdur ER is being used to alleviate my chest pain and it has done so completely. I have not have one single flair up at all since starting it! The only down fall is the headache that I have had. I am going to call my cardiologist today to see if I can take anything for that. I still give it a 10 even with the headache because the chest pain was worse than the headache!”

10 / 10
Granny · Taken for 6 months to 1 year July 20, 2019

Imdur (isosorbide mononitrate) for Heart Failure: “Dr started me on Imdur for angina/heart failure-after about 1 week, shortness of breath gone and I have no chest pain. I couldn't even turn over in bed without getting short of breath no side effects all-still taking after 6mths & feel great.”

10 / 10
Jackson · Taken for less than 1 month July 15, 2019

Imdur (isosorbide mononitrate) for Angina: “I was taking 30mg and the doc increased the Imdur to 60 mg now I have a headache, can’t sleep feel like everything is moving or spinning , and pain in my neck and my low back feels disconnected when in bed and all I want to do is vomit, it has been 2 days since the increase”

7 / 10
StanLee · Taken for less than 1 month July 10, 2019

For Angina: “I was prescribed these tablets -isosorbide 40mg Modified-Release tablets to be taken 1 each morning. 8-10 hours after taking my first tablet I had to go to bed with a terrible headache starting at the back of my head, into my neck. The pain spread across my shoulders and into my arms. It felt like severe arthritis, and couldn't get relief no matter how I tried. I can't remember ever feeling pain like it, and got very little sleep that night. Nothing could persuade me to take another one of these tablets. Dreadful medication.”

1 / 10
mackie NYC NY · Taken for 2 to 5 years June 11, 2020

For Angina: “Dr, put me on Isosorbide Mononitrate 60mg twice day, (did start with 30 twice day) I am 86 yrs have severe COPD. After reading 3 pages of reviews I am shocked at what other folks have had in side effects. I have had nothing in side effects that I am aware of and tightness in chest is now very rare. Have outstanding doctor for over 15 yrs. He gave me his cell phone years ago. He has made 2 house calls this year. I am really blessed. Been on med since Oct 2017.”

9 / 10
nana903 June 22, 2009

For Esophageal Spasm: “This medicine has saved my life after months of having chest pains everyday. I became weak and felt like I had nothing to live for. The doctors ruled out my heart and ruled I had esophageal spasms. They had tried other medications that did not work. My gastroenterologist gave me the time released IMDUR. IT HAS GIVEN ME MY LIFE BACK IN JUST OVER A WEEK. I HAVE MY ENERGY BACK AND I AM HAPPY TO SAY NO CHEST PAIN. THE ONLY SIDE EFFECT IS A HEADACHE BUT I CAN HANDLE THAT WITH TYLENOL. I HAVE MY LIFE BACK. THANK YOU SO MUCH.”

10 / 10
marklvnv July 4, 2011

For Angina Pectoris Prophylaxis: “My doctor prescribed this medicine due to on-going chest pain. I have now been taking it for 1 week and have a headache everyday. Nothing seems to help stop them. I have taken aspirin, Tylenol and even acetaminophen with codeine for relief and so far none have worked. The headache is constant throughout the day and is throbbing and causes dizziness. The good side is the chest pain has gone away. I'm considering stopping this medicine as the headaches are pretty bad.”

7 / 10
Mwk1 · Taken for less than 1 month September 8, 2020

For Angina: “Taken isosorbide mononitrate 30mg for 4 days. Had side effect of the most horrendous headache and neck pain and had to be sent home from work as pain was so bad. Lasted for about 8 hours. Not taking it tomorrow and will speak to Dr. Really confused about whether to continue with it. I expected a headache but this is ridiculous.”

Betboop June 7, 2015

For Angina Pectoris Prophylaxis: “I have been on this med for a couple months and I must say I feel sooooo much better! I have been fortunate in that I never had the headaches as have been reported in the reviews! My doctor just increased dose to 60 mg which has really helped me with my activity - no more shortness of breathe or pain! I have Angina and this med has helped big time! I have my quality of life back!”

10 / 10
Sue · Taken for 6 months to 1 year September 3, 2019

For Angina Pectoris Prophylaxis: “Jackson. My Dr put me on 30 mg and I had a killer headache all night so I wasn't going to take again but broke the tablet in half and took it. I still had a small headache. I suggest slowly increasing isosorbide until your body adjusts to it and then continue increasing until you reach the desired dose the dr wants you on. I told my cardiologist and he said that was ok..just a suggestion - you probably should check with your Doctor and see what they think.”

Tosca · Taken for 5 to 10 years January 22, 2020

For Angina: “Been taking extended release for five years. I had a pretty gnarly headache the first few days, was told to expect this, so that made it more tolerable. I have have had no side effects of note since then. Seems to help, although I have had angina occasionally while on it. My assumption here is I probably would have more angina without it.”

9 / 10
Shepherdess · Taken for less than 1 month February 20, 2018

For Angina: “I’ve got Prinzmetal Angina and my doctor put me on this medication after a particularly bad attack. I am already taking Amlodipine and GTN when required. The headache and neck ache from this medication has been severe. I can do nothing else but lay flat in a darkened room. No painkiller relieves it. If you are unlucky enough to get these side effects, they are horrendous. I persisted with it for a week, but it was disabling.”

Hud · Taken for less than 1 month June 26, 2019

For Angina: “I was prescribed this drug isosorbide mononitrate after going to hospital with angina. I was sick of using GTN spray, as it gave me sore throats & headaches. Only took these tablets 3x30 mg doses over 3 days & had to have a week off work. The side effects were dizziness, couldn't open my eyes or see properly, wasn't sure what I was doing, tired all the time - worst thing I've ever taken. Back to the spray & aspirin now. Rather have a few minutes angina ,than all the side effects of Carmil (UK brand of isosorbide). Never again. Just hope my appointment to have a stent fitted arrives soon.Been waiting since March.......”

1 / 10
savemyheart January 24, 2015

For Heart Failure: “I was exhausted and constantly gasping for breath. My cardiologist put me on isosorbide mononitrate, one pill a day. The difference was astounding. I no longer was gasping for breath and no longer had to take naps. The pill would wear off during the night so the doctor recently changed me to two/day. Am experiencing some pretty severe headaches and dizziness when get up to fast. Doctor had told me I would experience headaches but they would go away eventually.”

9 / 10
Cavalinesman · Taken for 1 to 6 months March 2, 2013

For Angina Pectoris Prophylaxis: “I have had great results with this medicine. I've been taking this for several months. The headaches have all but gone. "Guess I'm getting used to them". You need to hang in there with the headaches. The benefits are worth it.”

10 / 10
Sonny Beach November 3, 2015

Imdur (isosorbide mononitrate) for Angina Pectoris Prophylaxis: “I had chest pain and palpitations. Was prescribed Imdur and took 1 tablet. That was the worst 3 days of my life. I prefer the angina to the "cure." Caused nausea, vomiting, intense pain (felt like my body was made of broken glass), every sound went right thru me, and every noise was excruciating. Never again.”

1 / 10
Sally66 February 1, 2016

Imdur (isosorbide mononitrate) for Angina Pectoris Prophylaxis: “In bed 24 hours severe pain head to toe blurred vision vomiting light sensitive extreme this all happened on the day that I took imdur - I'm taking 30 milligrams the next day I was in bed till about 2 I felt 75% better did not take imdur called the doctor and told them what was going on would not recommend this medication to my worst enemy”

1 / 10
Babs · Taken for less than 1 month June 11, 2019

For Angina: “Started on Isosorbide mononitrate 30mg yesterday. Have had angina, SOB (shortness of breath), right hand and arm icy cold, since quad by-pass in 2017. Immediately after taking first dose felt "yukky", had the headache, dizzy, very tired, took an Ibuprofen and sat in recliner for about 2 hours, then felt much better and was able to walk in my yard with no chest pain (first since surgery)!. My right hand is warm! This morning took med then went back to bed for an hour. Slight headache right now. Will take Ibuprofen again. Still no chest pain or SOB. Right hand was cold, but is now warm again! I pray this continues.”

8 / 10
Lin · Taken for 10 years or more October 6, 2019

Imdur (isosorbide mononitrate) for Angina: “Dr increased me from 30 to 60 two days ago. Been on 30 for 17 years. Was no longer helping angina or high blood pressure. It seems to be helping pressure but having some chest pain. Also have severe COPD.”

10 / 10
Donaldw4 · Taken for 2 to 5 years January 15, 2020

For Angina Pectoris Prophylaxis: “I've been taking Isosorbide 30 mg ER dose 3 times a day for years to help angina. I also have a pacemaker. No headaches and I feel better than I did before this medicine was prescribed by my cardiologist.”

10 / 10
Theresahs59 September 25, 2017

For Angina: “I have been taking isosorbide mononitrate 30mg tablets for a little over 2 months now. For the first 4 to 5 days I did experience headaches, however, they did subside. I have, now, started to experience a headache every now and again though. I have, also, started to have the same chest pain, again, which had completely gone away until now. My biggest complaint and concern is that I find myself EXTREMELY tired, every single day, for the past 2 weeks! It does not matter if I sleep 8 or more hours I still wake up feeling like I have had no sleep at all! I can sit down on my couch or at the kitchen table and fall asleep sitting straight up and have slept that way for hours! I don't understand this but other that that I'm ok with the medicine.”

8 / 10
Phyllie · Taken for 1 to 6 months September 16, 2014

For Angina Pectoris Prophylaxis: “I have been on the medication about a month now. Fortunately, I have not had any headaches and the chest pain is gone for the most part. The side effects I have had are dizziness, sweats, feeling faint. So far, the good is outweighing the bad.”

8 / 10
Tahoe84ves September 13, 2017

For Angina: “The headaches caused by this medication is worse than the condition it is supposed to treat. The pain goes on for at least 24 is debilitating and cannot be treated with Tylenol or cool compresses...avoid this med at all costs!”

Mom · Taken for 1 to 6 months August 4, 2018

For Angina: “My daughter was put on this for her resistant high blood pressure. It does the job of lowering her pressure very well, but it makes her heart beat erratically and makes her feel terrible all of the time. Severe headaches, a weak, heavy feeling, nausea, dizziness and breathlessness. It is really a tough drug to take. We had to stop the extended release and go with the normal one that only lasts a few hours just to give her some relief. Once she gets more used to it we might go back to ext. release. But in the meantime, its completely debilitating.”

5 / 10
Sandinnalee1 · Taken for less than 1 month November 3, 2017

For Angina: “I've been on it 8 days. The dosage is 30 mg. I'm having stiff neck. The most terrible headache. It is for Angina. It is helping the chest pain. They say after a few weeks headaches will subside. I sure hope so.”

2 / 10

This information is NOT intended to endorse any particular medication. While these reviews might be helpful, they are not a substitute for the expertise, knowledge and judgement of healthcare practitioners.