Isosorbide mononitrate and Chest Pain: What Users Say

• The...
• September 25, 2017

For Angina "I have been taking isosorbide mononitrate 30 mg tablets for a little over 2 months now. For the first 4 to 5 days, I did experience headaches, however, they did subside. I have now started to experience a headache every now and again, though. I have also started to have the same chest pain again, which had completely gone away until now. My biggest complaint and concern is that I find myself EXTREMELY tired every single day for the past 2 weeks! It does not matter if I sleep 8 or more hours, I still wake up feeling like I have had no sleep at all! I can sit down on my couch or at the kitchen table and fall asleep sitting straight up and have slept that way for hours! I don't understand this, but other than that, I'm okay with the medicine."

• NCD...
• February 19, 2017

Isosorbide mononitrate for Angina Pectoris Prophylaxis "Took half dose, 15 mg, and spent two days feeling terrible. It caused chest and back pain, shortness of breath, confusion, dizziness, anxiety, and a general really sick feeling. It did relieve angina, but it was not worth the side effects. Really bad medicine."

• Lin...
• Taken for 10 years or more
• October 6, 2019

Isosorbide mononitrate for Angina "Dr. increased me from 30 to 60 two days ago. Been on 30 for 17 years. Was no longer helping angina or high blood pressure. It seems to be helping pressure but having some chest pain. Also have severe COPD."

• Lot...
• Taken for 1 to 6 months
• April 19, 2018

For Heart Failure "I recently had 2 stents placed in my heart. I was put on 60 mg ER Indur. I have been on it for 30 days. The headaches are horrendous, body aches, back pain, dizziness, extreme exhaustion, mental confusion. I feel like my brain is in a constant state of confusion. The headaches are still bad 30 days later. When I stopped taking the medication, all the symptoms eventually left, including my chest pains. I might have had better results if they had started me on a lower dose. I do not want to take this medication anymore."

• got...
• Taken for less than 1 month
• November 20, 2016

For Angina "My brother was put on this medication on Wednesday; yesterday (Saturday) he was taken to the ER with side effects from this. He felt like his chest was caving in, severe headache, couldn't get warm enough. His blood pressure went severely low, and his heart rate went high. He is still in the hospital today for observation. Would not recommend this drug to anyone."

• Anonymous
• Taken for 1 to 6 months
• May 29, 2024

For Angina "I have unstable angina and always felt very much at risk and vulnerable. Started taking isosorbide mononitrate and the first four days had terrible headaches. I knew this was possible and persevered. The headaches reduced in severity and within 10 days had stopped. No more severe chest pain. I have had a few mild episodes of chest pain, but not enough to use my GTN spray. I feel so much better and secure. Glad I persevered with them."

• Bre...
• Taken for 1 to 6 months
• July 15, 2021

For Angina "Was prescribed the ER tablet. Took it for three months, no problems. Then the excruciating headaches began, which were relieved by nothing... 24 hours a day. All I could do was stay in bed. When the pill was in effect for about only 8 hours a day, before the onset of headaches, I felt great, but when it wore off, I couldn't do anything. Everything caused chest pain. After the fourth month, the headaches were still excruciating, so I stopped taking it. Have had only one episode of angina since then, which seems to be brought on by stress. I just find I have to be careful not to overdo physically, and I do fine. This med has so many side effects you can't even count them all. I wondered if it was causing some strange adverse effect in my brain because the headaches didn't start until I had been on it about 3 months. Asked my cardiologist about this and why the delayed headache. His answer, 'I don't know.' Big help that was."