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Isosorbide mononitrate and Migraine: What Users Say

Migraine: mentioned by 4 users (3.7%)

Based on user experiences from 109 Isosorbide mononitrate reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

headaches 57.8%
dizziness 17.4%
nausea 11.0%
pain 9.2%
neck pain 8.3%
chest pain 6.4%
shortness of breath 5.5%
weakness 4.6%
back pain 3.7%
migraine 3.7%

Reviews for Isosorbide mononitrate

  • Wic...
  • Taken for less than 1 month
  • September 3, 2017

For Angina "I had a terrible experience on this drug. It was supposed to control my chest pain but instead worsened my pain. I also had migraines. In spite of these adverse reactions, my doctor wants me to try it again. No thank you."

1 / 10
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20 Report
  • Kel...
  • Taken for less than 1 month
  • August 8, 2021

Isosorbide mononitrate for Angina "Went to the ER last Sunday for chest pain/angina attack, couldn't walk up the stairs without feeling like I was having a heart attack, so the new cardiologist put me on Imdur 30 mg. The first day I was fine, the second day about 3 to 5 hours after taking it I came down with an ungodly migraine. I have been on it now for 6 days, and 5 of them I have had a migraine - not cool. But I have to admit that I'd rather have the headache because it has been heavenly being able to walk around with zero heart attack-like pain."

10 / 10
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9 Report
  • Rap...
  • Taken for 1 to 6 months
  • May 31, 2023

"I took this after a heart stent. I experienced swelling in my legs, and dry, itchy skin, hot, tingly skin, swelling in my face and throat, migraines, dizziness, nausea, dilated veins so much they appeared purple. Dosage 30 mg. Supposed to take it in the morning, but it made me so sick I took it at night."

1 / 10
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2 Report
  • Ano...
  • Taken for less than 1 month
  • August 23, 2025

"I took the first Imdur in early morning, within 2 hours, I had a horrible headache, neck pain, and shoulder pain. 60 mg dose. After 18 hrs, I still have severe neck pain and a horrible migraine. I haven’t slept and feel anxious."

1 / 10
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0 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.