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Isosorbide mononitrate User Reviews & Ratings (Page 3)

Isosorbide mononitrate has an average rating of 5.2 out of 10 from a total of 105 reviews on Drugs.com. 42% of reviewers reported a positive experience, while 45% reported a negative experience.

Reviews for Isosorbide mononitrate

Commonly mentioned side effects
  • bha...
  • Taken for 10 years or more
  • August 18, 2018

"I am told that I had IHD (ischemic heart disease) in the year 1977. I have never experienced angina or dyspnea or sweating, never in my life. After 20 years, when I had some burning sensation in my hands, my doctor prescribed Ismo 10 mg twice a day. Believe it or not, I have been taking this medicine for the last 22 years until my new cardiologist asked me to stop since I have been experiencing vertigo for the last 6 years. He said that nitrates may cause vertigo. Believe me, when I stopped the drug, from the first day itself, my vertigo and dizziness have gone."

10 / 10
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17 Report
  • LDi...
  • March 10, 2017

Isosorbide mononitrate for Angina "Was prescribed this medication by a new cardiologist while hospitalized to help with spasms associated with Prinzmetal's (variant) angina. So far, I feel a difference in my condition, but will form a more solid opinion when I'm on Imdur a bit longer."

7 / 10
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25 Report
  • Jac...
  • Taken for less than 1 month
  • August 2, 2017

For Angina "Was prescribed this after a heart attack and had a stent in. Have been taking just 30 mg of Carmel XL, and today will be my last day. Pounding headache, nothing can help. Can only lie down, every tiny movement hurts. Can't see properly. Not having angina attacks since surgery, so don't see the point of this medicine, surely a spray when needed is better? Would not recommend, but feel I have been misprescribed by the hospital."

1 / 10
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18 Report
  • Bos...
  • Taken for 1 to 2 years
  • October 5, 2021

For Angina "My husband was given isosorbide 2 years ago as he got so very anxious, etc. The hospital thought that this would stop him from having an angina attack, which it has, but the side effects are awful. He suffers from headaches, does not eat like he used to, and he loved his hot cooked home food, so that has gone, and will just eat a bowl of cereal for supper. We have a sandwich and a piece of cake at lunchtime, breakfast, and that is all. The other side effects include headache, feeling dizzy, not sleeping any longer than 2 hours each night, also complains of having a hot head, but not every day. He just sits and doesn't feel like doing anything, and I can understand if he is feeling like this. Also, his eyes run in the morning, but I think this is because he does not have enough sleep. I would desperately like him to come off these awful tablets, as his tests show that his heart, thank God, is alright, and his blood pressure now is where it should be. He also takes 1 aspirin each morning. Please help."

1 / 10
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10 Report
  • New...
  • Taken for less than 1 month
  • January 28, 2017

For Angina "I am only 39 and had my first heart attack on Jan 5th, 2017, caused by a 100% blockage and an 80% blockage. I go back on Jan 31st for another stent, and today, 1/28/17, is my first day taking the 30 mg isosorb mononitrate ER, and it's horrible so far. Bad headache all day, sick to my stomach, and heart palpitations all day. Really feeling like I should go to the ER. Do not recommend this medication."

2 / 10
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21 Report

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  • Anonymous
  • Taken for less than 1 month
  • October 17, 2022

For Angina "This medication was prescribed to help increase blood flow through a blocked artery (85-90% of the circumflex), although I'm fairly functional. I am also on Metoprolol for blood pressure and a recently prescribed statin, along with baby aspirin. I took 1/2 of my 30 mg pill yesterday and got an annoying headache. Today I took the full pill first thing in the morning and now have a really bad headache bordering on the feel of a migraine, minus the nausea-though I do feel a little queasy. I feel so bad that I am considering discontinuing it-though thanks to some of the reviews here, I will try to take it for a week before making that decision in case I can become accustomed to it. I have stable angina, so at this point, the horrible side effects are not worth it for the supposed benefit. I'd rather get winded and take it slower than be in the state I'm in."

1 / 10
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7 Report
  • Kel...
  • Taken for less than 1 month
  • August 8, 2021

Isosorbide mononitrate for Angina "Went to the ER last Sunday for chest pain/angina attack, couldn't walk up the stairs without feeling like I was having a heart attack, so the new cardiologist put me on Imdur 30 mg. The first day I was fine, the second day about 3 to 5 hours after taking it I came down with an ungodly migraine. I have been on it now for 6 days, and 5 of them I have had a migraine - not cool. But I have to admit that I'd rather have the headache because it has been heavenly being able to walk around with zero heart attack-like pain."

10 / 10
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9 Report
  • Anonymous
  • Taken for 1 to 6 months
  • May 29, 2024

For Angina "I have unstable angina and always felt very much at risk and vulnerable. Started taking isosorbide mononitrate and the first four days had terrible headaches. I knew this was possible and persevered. The headaches reduced in severity and within 10 days had stopped. No more severe chest pain. I have had a few mild episodes of chest pain, but not enough to use my GTN spray. I feel so much better and secure. Glad I persevered with them."

9 / 10
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3 Report
  • Nor...
  • Taken for 10 years or more
  • November 13, 2016

For Angina "I have been treated since heart attacks and bypass surgery. I also suffer from Raynaud's disease, and before isosorbide, my hands caused so much pain. Turning white, blue, then red. Very painfully if it’s cold, even indoors, I wear gloves. But since isosorbide, my hands stay pretty normal. Love it."

10 / 10
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15 Report
  • Bre...
  • Taken for 1 to 6 months
  • July 15, 2021

For Angina "Was prescribed the ER tablet. Took it for three months, no problems. Then the excruciating headaches began, which were relieved by nothing... 24 hours a day. All I could do was stay in bed. When the pill was in effect for about only 8 hours a day, before the onset of headaches, I felt great, but when it wore off, I couldn't do anything. Everything caused chest pain. After the fourth month, the headaches were still excruciating, so I stopped taking it. Have had only one episode of angina since then, which seems to be brought on by stress. I just find I have to be careful not to overdo physically, and I do fine. This med has so many side effects you can't even count them all. I wondered if it was causing some strange adverse effect in my brain because the headaches didn't start until I had been on it about 3 months. Asked my cardiologist about this and why the delayed headache. His answer, 'I don't know.' Big help that was."

1 / 10
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8 Report
  • Ken...
  • Taken for less than 1 month
  • October 10, 2022

For Angina "I was prescribed this medicine - isosorbide 30 mg. First, I thought something was wrong with me. After a couple of days, I started having headaches, dizziness, nasal pain, and pain spread across my arm, shoulder, and back. Trying to walk around the house, I cannot balance well, afraid of falling down. I need to stay in bed. I felt fatigued. I found out this was a side effect of the isosorbide medicine. What kind of medicine tries to accomplish more harm than help? Dreadful medication."

1 / 10
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7 Report
  • Doc...
  • Taken for 1 to 6 months
  • April 24, 2018

For Angina "I have been on this drug for 6 months. 30 mg. I have not experienced any side effects. Recently increased the amount to 60 mg, and the first few days I was very dizzy and felt weak. I am confident I will get used to the higher dosage."

9 / 10
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14 Report
  • It ...
  • Taken for 2 to 5 years
  • May 6, 2017

For Angina Pectoris Prophylaxis "No more! Everything upsets me on this med! Always irate, temperamental. Dry mouth so bad - had 4 teeth pulled. Cry, cry, cry. I'm so angry 'doc' never listened, shame on you, all of you, it's my body, and you ruined it forever!"

1 / 10
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21 Report
  • Cin...
  • Taken for less than 1 month
  • January 16, 2025

Isosorbide mononitrate for Angina "Was put on Imdur (1/2 30 mg tab) after heart catheterization. Worst 6 days of my life. I tried to wait out the week for my system to acclimate to the meds, but I couldn't do it. I would take the meds at 6 a.m. and by 8 a.m. I would have the worst headache. Nothing helped. I tried everything: Tylenol, heat packs, cold packs, even my migraine cocktail. By day 6, it was so bad I had to go to the ER for a shot of Toradol. I was completely down for 6 days. Doctor finally discontinued Imdur and is trying something else. This may work for some, but not for me."

1 / 10
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1 Report
  • Wen...
  • June 30, 2018

For Esophageal Spasm "I have no pain, but at a swallow test, was diagnosed with esophageal spasms along with a small hiatal hernia. I am having a lump-like feeling in my throat when I make saliva, but not when I eat or drink. I was prescribed half of a 30 mg tablet daily. I have taken it twice and got a headache, but not a really bad one. I’m wondering if I even need to take it."

1 / 10
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12 Report
  • Jay...
  • Taken for 1 to 6 months
  • December 11, 2024

For Heart Failure "Terrible, terrible headaches. I took the medicine at 4am, and it’s now 7:45am. I’m contemplating calling off from work because I’m not sure I can function. My cardiologist prescribed 120 mg. So last night I had one, and my heart rate was beating so fast. I toss all night long. Heartburn, and I felt acid reflux. The headaches are just terrible. My chest pain is gone, but the headache is still present. I’ve been without this medicine for a month, and I wonder if that’s the reason for the reaction I’m having."

7 / 10
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1 Report
  • Tan...
  • Taken for less than 1 month
  • November 14, 2021

For Angina "Dr. prescribed Ismo 30 mg, and after taking it, I felt so much head and neck pain, but I slept right away. The next day, no headache was felt, but my neck and shoulders were really hurting. Then, after a few minutes, my heart started pounding fast, and I felt like I was losing my breath. This went on for hours. I could not sleep because of difficulty in breathing, and my heart was palpitating through the night. I can't sleep. It felt like my heart was racing. I feel restless and like I have insomnia. I stopped the med after that 1 dose. I will go to another doctor for a second opinion."

1 / 10
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5 Report
  • ceb...
  • Taken for 1 to 2 years
  • January 22, 2022

For Angina Pectoris Prophylaxis "I have been taking isosorbide mononitrate for over a year now for stable angina pectoris. I take it at 10 A.M. in the morning rather than when I get up, which works best for me because its effect only lasts 9 hours for me, and if I take it too early, I have a severe rebound period beginning at about the 9-hour mark... eating the evening meal at 6 P.M. causes a hard angina attack if I am in the rebound period. In my rebound period, walking 50-60 feet or any similar activity brings on an attack, and I have to take one 0.4 mg nitroglycerin sublingual tablet as a minimum, and if I don't catch it early, two or three nitro tabs. My rebound period is most problematic from about 9 hours to 14 hours after taking the drug. In the mornings after resting overnight, I'm good."

9 / 10
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4 Report
  • 3...
  • Taken for less than 1 month
  • January 1, 2022

For Angina "After leaving the hospital, I was prescribed isosorbide mononitrate. I took 1, and the headache was so severe I couldn't sleep, and it lasted 8 hours. Had to take aspirin to get it manageable. Waited a day to understand what just happened. On the third day (today), I cut the pill in half and tried again. At 10 am, I took it, and by 12:30, I started getting dizzy, and the headache returned like a three-penny nail. It is now 6 pm, and it is now manageable. Seriously, I DON'T think I can deal with this."

1 / 10
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5 Report
  • Sta...
  • Taken for less than 1 month
  • March 6, 2022

For Angina "Was on a 30 mg tablet with no side effects, now on 60 mg and get the most horrendous headaches. Paracetamol, ibuprofen, or any other pain reliever is useless as they don't work. Would have thought that in this day and age they could produce something that has no side effects."

3 / 10
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3 Report
  • Caz...
  • Taken for 2 to 5 years
  • March 10, 2022

For Angina "I've been 3 years on 60 mgs now, and the last few months started to feel very ill. I have frozen shoulder, and after 3 months of acupuncture and chiropractor, it's not getting better. Along with headaches, back ache, and a general constant feeling of life being drained out of me. This situation is making me very depressed and feeling hopeless. I did try to cut the pills in half for a week and became so ill and unable to stand I have had to go back on them. I will now try to wean off them in smaller doses as I cannot keep existing like this. The cardiologist had said no way in stopping taking them, he was adamant. Then when I said I'd had frozen shoulder for the last few months, he was 'oh, you got frozen shoulder, ok, stop taking them.' It was ONLY THEN that I looked at side effects, and frozen shoulder is or can be one of them... It's been SO debilitating, I'm at my wits' end to think this could largely be because of medication... leaves me totally frustrated."

3 / 10
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3 Report
  • Rap...
  • Taken for 1 to 6 months
  • May 31, 2023

"I took this after a heart stent. I experienced swelling in my legs, and dry, itchy skin, hot, tingly skin, swelling in my face and throat, migraines, dizziness, nausea, dilated veins so much they appeared purple. Dosage 30 mg. Supposed to take it in the morning, but it made me so sick I took it at night."

1 / 10
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2 Report
  • Wic...
  • July 14, 2021

For Angina "I’ve got angina and have been prescribed this drug, 10 mg twice a day. Horrendous headache that just lasts all day, every day. Taking paracetamol, but I’m worried about having to take too much. Will ask my GP about it at check-up."

4 / 10
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3 Report
  • ceb...
  • Taken for 1 to 2 years
  • June 11, 2022

For Angina Pectoris Prophylaxis "I have been taking 60 mg of the extended-release isosorbide mononitrate for more than a year. For me, it works for 9.5 to 10 hours, and then I have a 'rebound' period of about 4 hours where I can't do anything but sit still and avoid any stress at all, or I have an angina attack. The rebound period has been getting worse the past couple of months, and I have had attacks while sitting doing nothing. I take the dose at 10 o'clock a.m. so that the rebound won't start until 7:30 - 8:00 in the evening. I have had to start taking 0.4 mg nitroglycerin at 8 o'clock and again at 9:30 to get through the evening without an attack."

8 / 10
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2 Report
  • Ben...
  • Taken for 2 to 5 years
  • May 11, 2022

For Angina "I’ve been taking the medicine since 2019 after a heart attack for angina. 30 mg once a day. Unfortunately, if I stop it, there is a withdrawal, and the pain comes back. So I need to keep on taking it. Headache and dizziness are bad."

8 / 10
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2 Report

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