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Doxazosin Side Effects

Medically reviewed by Last updated on Mar 29, 2024.

Applies to doxazosin: oral tablet, oral tablet extended release.

Serious side effects of Doxazosin

Along with its needed effects, doxazosin may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur while taking doxazosin:

More common

Less common


Incidence not known

Other side effects of Doxazosin

Some side effects of doxazosin may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Less common

Incidence not known

For Healthcare Professionals

Applies to doxazosin: oral tablet, oral tablet extended release.


The most common adverse reaction was dizziness.[Ref]

Nervous system

Very common (10% or more): Dizziness (up to 19%)

Common (1% to 10%): Somnolence, headache, vertigo

Uncommon (0.1% to 1%): Cerebrovascular accident, hypoesthesia, syncope, tremor, tinnitus

Very rare (less than 0.01%): Dizziness postural, paresthesia

Frequency not reported: Taste disturbance[Ref]


Very common (10% or more): Fatigue/malaise (12%)

Common (1% to 10%): Asthenia, chest pain, influenza-like symptoms

Uncommon (0.1% to 1%): Pain, facial edema[Ref]


Common (1% to 10%): Dyspnea, rhinitis, respiratory tract infection, bronchitis, cough

Uncommon (0.1% to 1%): Epistaxis

Very rare (less than 0.01%): Bronchospasm

Postmarketing reports: Bronchospasm aggravated[Ref]


Common (1% to 10%): Dry mouth, abdominal pain, dyspepsia, nausea

Uncommon (0.1% to 1%): Constipation, flatulence, vomiting, gastroenteritis, diarrhea

Frequency not reported: Gastrointestinal obstruction[Ref]


Common (1% to 10%): Polyuria, urinary tract infection, cystitis, urinary incontinence

Uncommon (0.1% to 1%): Dysuria, micturition frequency, hematuria, impotence

Very rare (less than 0.01%): Micturition disorder, nocturia, priapism

Frequency not reported: Retrograde ejaculation[Ref]


Common (1% to 10%): Hypotension, postural hypotension, palpitation, tachycardia

Uncommon (0.1% to 1%): Angina pectoris, myocardial infarction

Very rare (less than 0.01%): Bradycardia, cardiac arrhythmias, hot flushes[Ref]


Common (1% to 10%): Edema, peripheral edema

Uncommon (0.1% to 1%): Gout, appetite increased, anorexia, weight increased[Ref]


Common (1% to 10%): Myalgia, back pain

Uncommon (0.1% to 1%): Arthralgia

Rare (less than 0.1%): Muscle cramps, muscle weakness[Ref]


Common (1% to 10%): Pruritus

Uncommon (0.1% to 1%): Skin rash

Very rare (less than 0.01%): Urticaria, purpura, alopecia[Ref]


Uncommon (0.1% to 1%): Agitation, depression, anxiety, insomnia, nervousness

Frequency not reported: Libido decreased[Ref]


Uncommon (0.1% to 1%): Abnormal liver function tests

Very rare (less than 0.01%): Cholestasis, hepatitis, jaundice

Postmarketing reports: Hepatitis cholestatic[Ref]


Uncommon (0.1% to 1%): Allergic drug reaction

Postmarketing reports: Allergic reaction[Ref]


Very rare (less than 0.01%): Leukopenia, thrombocytopenia

Frequency not reported: White blood cell counts decreased, neutrophil count decreased[Ref]


Very rare (less than 0.01%): Blurred vision

Frequency not reported: Intraoperative Floppy Iris Syndrome (IFIS)[Ref]


Very rare (less than 0.01%): Gynecomastia[Ref]


Very rare (less than 0.01%): Diuresis increased[Ref]


1. (2001) "Product Information. Cardura (doxazosin)." Pfizer U.S. Pharmaceuticals

2. Cerner Multum, Inc. "UK Summary of Product Characteristics."

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.