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Sular

Generic Name: nisoldipine (nye ZOL di peen)
Brand Name: Sular

What is Sular (nisoldipine)?

Nisoldipine is calcium channel blocker that relaxes (widens) blood vessels and improves blood flow.

Nisoldipine is used to treat high blood pressure (hypertension).

Nisoldipine may also be used for purposes not listed in this medication guide.

What is the most important information I should know about Sular (nisoldipine)?

Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

What should I discuss with my healthcare provider before taking Sular (nisoldipine)?

You should not use this medicine if you are allergic to nisoldipine, or to similar medications such as amlodipine, felodipine, nicardipine, nifedipine, or nimodipine.

To make sure nisoldipine is safe for you, tell your doctor if you have:

  • coronary artery disease;

  • congestive heart failure;

  • liver disease; or

  • asthma, or a history of severe allergic reaction (sneezing, runny or stuffy nose, wheezing, shortness of breath) after taking aspirin.

It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

It is not known whether nisoldipine passes into breast milk or if it could affect the nursing baby. Tell your doctor if you are breast-feeding.

Nisoldipine is not approved for use by anyone younger than 18 years old.

How should I take Sular (nisoldipine)?

Follow all directions on your prescription label. Your doctor may occasionally change your dose. Do not use this medicine in larger or smaller amounts or for longer than recommended.

Take nisoldipine on an empty stomach, at least 1 hour before or 2 hours after a meal.

Do not crush, chew, or break a nisoldipine tablet. Swallow it whole.

Your blood pressure will need to be checked often.

Keep using this medicine as directed, even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medicine for the rest of your life.

Store at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking Sular (nisoldipine)?

Grapefruit and grapefruit juice may interact with nisoldipine and lead to unwanted side effects. Avoid the use of grapefruit products while taking nisoldipine.

Sular (nisoldipine) side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • a light-headed feeling, like you might pass out;

  • swelling in your legs or ankles;

  • pounding heartbeats or fluttering in your chest; or

  • chest pain or pressure, pain spreading to your jaw or shoulder.

Common side effects may include:

  • headache, dizziness;

  • sore throat, sinus pain;

  • rash; or

  • nausea.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Sular (nisoldipine)?

Tell your doctor about all your current medicines and any you start or stop using, especially:

  • any other heart or blood pressure medicines;

  • cimetidine;

  • imatinib;

  • nefazodone;

  • St. John's wort;

  • an antibiotic--clarithromycin, telithromycin;

  • antifungal medicine--itraconazole, ketoconazole, posaconazole, voriconazole;

  • antiviral medicine to treat hepatitis or HIV/AIDS--atazanavir, boceprevir, cobicistat, delavirdine, efavirenz, fosamprenavir, indinavir, nelfinavir, ritonavir, saquinavir;

  • seizure medicine--carbamazepine, phenytoin; or

  • tuberculosis medicine--isoniazid, rifampin.

This list is not complete and many other drugs can interact with nisoldipine. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Give a list of all your medicines to any healthcare provider who treats you.

See also: Side effects (in more detail)

Where can I get more information?

  • Your pharmacist can provide more information about nisoldipine.
  • Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
  • Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2012 Cerner Multum, Inc. Version: 6.01.

Date modified: October 13, 2017
Last reviewed: April 03, 2017

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