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User Reviews for Glycopyrronium topical to treat Hyperhidrosis

Also known as: Qbrexza

Glycopyrronium topical has an average rating of 5.8 out of 10 from a total of 37 ratings for the treatment of Hyperhidrosis. 41% of reviewers reported a positive experience, while 30% reported a negative experience.

Glycopyrronium topical rating summary

5.8/10 average rating

37 ratings from 40 user reviews.

Compare all 15 medications used in the treatment of Hyperhidrosis.

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Reviews for Glycopyrronium topical

BooBoo · Taken for less than 1 month · April 19, 2021

Qbrexza (glycopyrronium): “Tried Qbrexza for underarm sweating. This product does what it’s supposed to - it stops sweating. However, the side effects are simply not worth it. I had severe dry mouth and nose within 4hrs of using under my arms. I did not sweat anywhere else either - hands, face, groin, feet, for that matter. I could barely talk or swallow and drank/sipped water constantly. It’s now been 14 hours since initial application and I’m up at 3:30am unable to sleep due to this dry mouth. I had to skip dinner because I had zero saliva to help breakdown my food. My eyes are also looking red and dry, but I’m not ‘feeling’ any issue with them. This dry mouth is incredibly horrible though. Had I have known it was going to be this severe, I’d have passed in a heartbeat. After all the water I have drank in the past 14 hours - literally over 1.5 gallons, I am worried as peeing is getting increasing difficult.”

2 / 10
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DDBMD · November 3, 2020

Qbrexza (glycopyrronium): “I'm an ER doc, taking Adderall since high school. I tried older meds first for my hyperhidrosis, Robinul & Oxybutynin, both failed, were terrible, did nothing for sweating. Once Qbrexza was introduced I was amongst the first to try it and it truly works 100%. Although FDA approved for underarm sweating, it has stopped all my sweating. Since there is no generic, a month supply costs somewhere around $700.00 if paying cash. Thus, insurance companies may not cover it at first if you haven't tried the cheap meds (referenced above) first. The best way to get it covered by your insurance is to have your Dermatologist document in their progress note that you are a 4 on the HDSS (Hyperhidrosis Disease Severity Scale), Google it and it will be one of the first results. This is a surefire way to get your insurance plan to cover it, especially when a prior authorization and or/ medical necessity review is required. I've never had/ heard of/ learned of a solution to stop the Adderall sweats until this med came out.”

10 / 10
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CC · Taken for less than 1 month · July 12, 2019

Qbrexza (glycopyrronium): “Used to have to wear panty liners in my shirts to cover armpit sweat. Could be 100 degrees or -18 and I was pitting out! Been on for almost two weeks, soooooo much better!!!!!!! I have had none of the side effects, not one. Try this product! Its a game changer!”

9 / 10
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Jill · Taken for less than 1 month · September 7, 2019

Qbrexza (glycopyrronium): “Qbrexza works! There are side effects, but they are manageable. I use Qbrexza every other day and limit my swipes to one per area. I also use an all natural deodorant (non-aluminum) to minimize dry itchy skin. Since using Qbrexza, I am gaining a confidence that I never thought I would have!”

9 / 10
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BKG123 · Taken for 6 months to 1 year · September 18, 2019

Qbrexza (glycopyrronium): “Have been using Qbrexza for six months for underarm sweating. Was working great. In the past two weeks though, the side effects have come out of nowhere & hit me hard. Excessive dry mouth to the point of choking on food, urinary problems, blurred vision & inability to sweat. I was working out, doing my normal routine & spiked a crazy high fever. At first I thought it was the flu but I was fine the next day. Went to workout tonight, same thing happened & my coach noticed I wasn’t sweating. Stopping immediately. Will be calling my dermatologist tomorrow!”

4 / 10
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Chuchi · Taken for less than 1 month · February 9, 2020

Qbrexza (glycopyrronium): “Horrible!! Be careful if you use this on teenagers or young children. My daughter is 13 she used ONE ! one! wipe she ended up in the emergency room bladder blockage and her mouth inside turn white and super dry. She wasn’t able to eat or drink for over 48 hours. She was telling me she wants to cry and she was so dry no tear will come out. The medicine was over $500!! Plus the emergency room and the doctors appointment to follow up plus the medicine to get her back to normal over $3000 in hospital deductible. I contact the manufacturer and I only get I’m sorry that happened to her. A least reimbursed the medication but not. Is a very expensive risk and put your child in risk not worse it!!!!”

1 / 10
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Ri · Taken for 6 months to 1 year · May 21, 2020

Qbrexza (glycopyrronium): “HOLY MOLY. I used to use this product off and on cause I would forget about applying it at night but since quarantine hit I decided to actually have a night time routine and I started using one pad a day regularly and I noticed I stopped sweating... everywhere. It was so weird cause I’ve sweat literally everywhere (mostly my underarms) for all of my life. I have always suffered from hyperhidrosis. Anyway, one morning I woke up with the WORST dry mouth I have EVER experienced. To the point where I was choking. My throat was so sore it was unbearable and my vision was so blurred. I am literally depressed cause this actually stopped my sweating but the side affects are just too much to handle.”

6 / 10
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Frequently asked questions

Steve · Taken for 1 to 6 months · July 19, 2020

Qbrexza (glycopyrronium): “First day on Qbrexza I woke up with dried throat, next day I decided to use it around 5pm and drink a lot of water and I had no issues. I know side effects might vary but 4 months in and only side effect is dry throat once in a blue moon. Literally the best thing ever, I can finally wear normal clothes.”

10 / 10
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KT · Taken for 1 to 6 months · June 20, 2019

Qbrexza (glycopyrronium): “The drug was great at eliminating my sweat problem, but at what cost? I experience almost all side effects even the severe. I got hives and was given several antihistamines from doctors because they couldn't figure out why they wouldn't go away. Later to find out that antihistamines have a negative reaction when taken with Qbrexza so my hives just kept getting worse. Since then, I've experienced terrible dry mouth, urinary tract issues and just this week began experience blurred vision. Went to the eye doctor and he confirmed it was probably the medication since my pupils were incredibly dilated which is also a side effect of the medication. I've never had an allergic reaction to any kind of medication. I wish I didn't have this experience with this medication since it does seem to work.”

4 / 10
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TT · Taken for less than 1 month · July 6, 2019

Qbrexza (glycopyrronium): “I used this "off label" as a sample from my dermatologist for hyperhidrosis of the groin region. It was the easiest, non-irritating, best working product I have ever tried. I felt so free & confident to wear whatever type of pant I wanted without embarrassing sweat. I totally wish you could get this as a prescription for excessive sweating in the groin, but insurance only covers it for axillary hyperhidrosis. Totally bummed because it totally works!”

10 / 10
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Alex · Taken for less than 1 month · June 26, 2020

Qbrexza (glycopyrronium): “First night with Qbrexza just 1 wipe and I am having have of the side effects, dry mouth, dry nose, itchy throat, blurred vision. This isn't worth the risk. Now I'm up 3am in the morning writing this cause I'm uncomfortable and can't go to sleep due to excessive dry mouth and nose.... Ugh... Aggravating... I will never try it again”

1 / 10
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cas7491 · Taken for 1 to 2 years · October 26, 2020

Qbrexza (glycopyrronium): “I had been on drysol for years (I'm in my 30s); however, it was becoming increasingly difficult for my pharmacy to get and the itching on application nights would keep me up. My dermatologist suggested Qbrezxa and I've been pleased, especially as I find the wipes far easier to apply than drysol. I have a little itching after application, but it's nothing compared to what I experienced with drysol. I did have severe dry mouth and throat irritation during the first week or so, but I increased my water intake and this drastically decreased (possibly as my body adjusted to the medication). Everyone responds to medications differently, but for me, the benefits far outweigh the risks.”

10 / 10
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YaGirrrl · Taken for less than 1 month · July 4, 2019

Qbrexza (glycopyrronium): “So I have definitely noticed a decrease in underarm sweating, not as much as I wish but I guess anything is an improvement. But I want to warn anyone that uses this, WASH YOUR HANDS!!! I put this on right before bed and forgot to wash my hands. I woke up in the night and realized my contacts were still in so I took them out. Fast forward to the next morning, I looked in the mirror and my eyes were dilated so big they looked almost completely black! Stayed that way almost all day and going outside into the sun was almost unbearable, I had to wear my glasses and then sunglasses on top, not to mention I looked like I had been nose deep in cocaine that morning. Follow the directions!!!”

8 / 10
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A · Taken for less than 1 month · February 6, 2021

Qbrexza (glycopyrronium): “I used this medication for a week, and it really worked. However, on day 5 got every single side effect to the extreme. Dry mouth, throat, eyes, nose, blurred vision, distended bladder and trouble urinating. I also stopped sweating from all other parts of my body, and when I exercised, my face got extremely red and I began overheating. The benefits are absolutely not worth enduring the side effects. I won’t even continue trying to stick this out to see if they go away.”

1 / 10
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Latina_787 · Taken for less than 1 month · May 10, 2019

Qbrexza (glycopyrronium): “Qbrexza started to work for my sweating right away. I did experience some dryness of the mouth and throat but it goes away as the day progresses. Lots of water is a very important factor, the water helps with dryness and constipation. My experience is way better than I had expected from the medicine.”

10 / 10
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Gee · Taken for less than 1 month · July 27, 2019

Qbrexza (glycopyrronium): “Worked for my hyperhidrosis of the palms. My dermatologist suggested to give it a try at night and use one of those wipes in each palm. Provided me with free samples. Worked to get rid of the sweat but the side effect of this medication is horrible. Blurred vision, dilated pupils and very sensitive to the light. I’ll take the sweat any time over those side effects! Would not use again!”

6 / 10
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Jules · Taken for 1 to 6 months · April 7, 2020

Qbrexza (glycopyrronium): “I have been using Qbrexa for a few months now and it works great! I was using it every day, and did experience dry mouth at times, so I switched to every other day and it made a world of difference! I have even found that lately I can go a few days or even a week without using it and I still stay dry. I would recommend spacing it out if the side effects become too much. Definitely wear gloves when you apply it, to avoid unnecessary contact with other parts of your skin.”

10 / 10
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Ryan · Taken for less than 1 month · July 13, 2019

Qbrexza (glycopyrronium): “Worked amazing from day 1, however the side effects were horrible. Excessive dry mouth, couldn’t even eat. Dilated pupils, extremely sensitive to sun. Also stopped sweating from everywhere no matter how hot it was. This is scary and could lead to heat stroke quickly. My doc told me to discontinue immediately. Very upset by this as it’s the first thing that has ever stopped my underarm sweating.”

4 / 10
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Smitty · Taken for 1 to 6 months · October 6, 2021

Qbrexza (glycopyrronium): “It works… if you can afford it. After my samples ran out, my insurance check Monat denied my prior authorization. The pharmacy wanted $1000 for a 30 day supply. You read that right. $1000 for something the size of an alcohol wipe. So frustrating. I finally find something that works and it’s so overpriced. I guess I’ll just sweat until 2033 when it goes generic.”

9 / 10
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Olive · Taken for 6 months to 1 year · May 23, 2020

Qbrexza (glycopyrronium): “I use Qbrexa under my arms and it has seriously changed my life. I’m allergic to aluminum so most other options just made my sweating worse. I’m a young college student so I also didn’t want to try any pill that might have other lasting side effects. I think it’s important to follow the directions EXACTLY. Only one swipe per area, wash hands immediately. Doing anything outside of that exactly has given me the side effects others have complained about. I did have dry mouth when I first started it, but it went away within about a week of use. I did sort of struggle to get my insurance to cover this expensive drug and it had to come from a specialty pharmacy, but it’s been completely worth it. I can wear sweaters and I don’t have to wash the straps of my book bag of sweat anymore.”

10 / 10
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Marylander · Taken for less than 1 month · January 9, 2020

Qbrexza (glycopyrronium): “Worked great the first week and then I got the most horrible rash that keeps getting worse and is spreading although I stopped taking the medication 10 days ago. My mouth began to get so dry to the point of choking. I am still itchy, red and irritated and the rash is spreading down my arms and breasts. Qbrexza stops the sweating but the side effects are dangerous.”

3 / 10
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Sunset · Taken for less than 1 month · July 3, 2021

Qbrexza (glycopyrronium): “My dermatologist told me about the wipes I never knew about them, she gave me 2 weeks of samples and I literally noticed the difference within the first 3 days. I have suffered for 18 years and now it feels amazing to be have dry underarms! I can wear white shirts again, I can wear anything! However, I do notice the dry mouth at times. Just drink lots of water and ONLY wipe once per arm when I wipe more than once the dry mouth is worst. Truly a change in my life.”

10 / 10
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LS · September 16, 2019

Qbrexza (glycopyrronium): “I used it once as directed and the side effects I had were horrible, I almost passed out. My hands and face got swollen and red, I had the excessive dry mouth and throat, couldn’t even drink water, and terrible headache for 24 Hours. I've never had an allergic reaction to any kind of medication before.”

1 / 10
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sabs · Taken for less than 1 month · May 8, 2021

Qbrexza (glycopyrronium): “Worked a little bit too well, always try before you buy! I got a sample of Qbrexza from my dermatologist. I followed the directions (washing my hands to make sure it didn’t get into my mouth or eyes), used it on my underarms and within 4 hours I had a super dry throat! Could barely talk. When I woke up the next day, it was the worst thing ever. My mouth and throat were so dry and swollen I felt like I was choking trying to breathe. I couldn’t drink anything because it hurt so badly to swallow. My tongue was bright white and my eyes bright red. Everything hurt so badly I wanted to cry (but I couldn’t)! It worked well for sweating, but I recommend you try it out to see how you react before getting a full prescription... As someone who tends to be a bit more sensitive to drugs and a teen, I will not continue using :(”

4 / 10
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DDBMD · Taken for 1 to 6 months · April 6, 2020

Qbrexza (glycopyrronium): “Overall, A- experience. At initial use, caused a little excess drying near the underarms - went away in about a week. I am on my third month of Qbrexza and have no side effects. I am also using it on my feet (off label). It has cured my underarm and foot sweat. I don't use it every day. Not sure if it makes sense outside of my head, but I can feel if it's going to be a sweaty day or not. Based on that, I may only need to use a wipe every second or third day. Prior to starting Qbrexza I was on glycopyrrolate and oxybutynin - both dried me out 200% - I give them both an F-. Qbrexza is the way to go.”

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This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge and judgement of healthcare professionals.

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