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Medications for Facial Wrinkles

Other names: Canthal Lines; Lateral Canthal Lines; Nasolabial Folds; Smile Lines; Wrinkles

Facial wrinkles are creases in the skin of the face.

See also: sub-topics

Drugs used to treat Facial Wrinkles

The following list of medications are in some way related to or used in the treatment of this condition.

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Drug name Rating Reviews Activity ? Rx/OTC Pregnancy CSA Alcohol
Botox Cosmetic 5.2 13 reviews for Botox Cosmetic to treat Facial Wrinkles
Rx C N

Generic name: onabotulinumtoxinA systemic

Drug class: skeletal muscle relaxants

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Botox 4.7 3 reviews for Botox to treat Facial Wrinkles
Rx C N

Generic name: onabotulinumtoxinA systemic

Drug class: skeletal muscle relaxants

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

tazarotene 9.0 2 reviews for tazarotene to treat Facial Wrinkles
Rx X N

Generic name: tazarotene topical

Brand name:  Avage

Drug class: topical acne agents, topical antipsoriatics

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

onabotulinumtoxinA 5.2 18 reviews for onabotulinumtoxinA to treat Facial Wrinkles
Rx C N

Generic name: onabotulinumtoxinA systemic

Brand names:  Botox Cosmetic, Botox

Drug class: skeletal muscle relaxants

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph

Dysport 4.2 6 reviews for Dysport to treat Facial Wrinkles
Rx C N

Generic name: abobotulinumtoxinA systemic

Drug class: skeletal muscle relaxants

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Juvederm 4.5 12 reviews for Juvederm to treat Facial Wrinkles
N U

Generic name: dermal filler topical

For consumers:

Restylane 1.0 4 reviews for Restylane to treat Facial Wrinkles
N U

Generic name: dermal filler topical

For consumers:

Avage Rate Add review
Rx X N

Generic name: tazarotene topical

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Xeomin 7.3 3 reviews for Xeomin to treat Facial Wrinkles
Rx C N

Generic name: incobotulinumtoxinA systemic

Drug class: skeletal muscle relaxants

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Radiesse 7.0 2 reviews for Radiesse to treat Facial Wrinkles
N U

Generic name: dermal filler topical

For consumers:

azficel-t Rate Add review
Rx C U

Generic name: azficel-t systemic

Brand name:  LaViv

For consumers:

abobotulinumtoxinA 4.2 6 reviews for abobotulinumtoxinA to treat Facial Wrinkles
Rx C N

Generic name: abobotulinumtoxinA systemic

Brand name:  Dysport

Drug class: skeletal muscle relaxants

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph

LaViv Rate Add review
Rx C U

Generic name: azficel-t systemic

For consumers:

Perlane Rate Add review
N U

Generic name: dermal filler topical

For consumers:

incobotulinumtoxinA 7.3 3 reviews for incobotulinumtoxinA to treat Facial Wrinkles
Rx C N

Generic name: incobotulinumtoxinA systemic

Brand name:  Xeomin

Drug class: skeletal muscle relaxants

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph

Captique Rate Add review
N U

Generic name: dermal filler topical

For consumers:

Hylaform Plus Rate Add review
N U

Generic name: dermal filler topical

For consumers:

Skinvive by Juvéderm Rate Add review
Rx U

Generic name: hyaluronic acid/lidocaine systemic

For consumers:

Bellafill 2.8 47 reviews for Bellafill to treat Facial Wrinkles
N U

Generic name: dermal filler topical

For consumers:

Frequently asked questions

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Topics under Facial Wrinkles

Learn more about Facial Wrinkles

Mayo Clinic reference

Legend

Rating For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).
Activity Activity is based on recent site visitor activity relative to other medications in the list.
Rx Prescription only.
OTC Over-the-counter.
Rx/OTC Prescription or Over-the-counter.
Off-label This medication may not be approved by the FDA for the treatment of this condition.
EUA An Emergency Use Authorization (EUA) allows the FDA to authorize unapproved medical products or unapproved uses of approved medical products to be used in a declared public health emergency when there are no adequate, approved, and available alternatives.
Expanded Access Expanded Access is a potential pathway for a patient with a serious or immediately life-threatening disease or condition to gain access to an investigational medical product (drug, biologic, or medical device) for treatment outside of clinical trials when no comparable or satisfactory alternative therapy options are available.
Pregnancy Category
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act (CSA) Schedule
M The drug has multiple schedules. The schedule may depend on the exact dosage form or strength of the medication.
U CSA Schedule is unknown.
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

Further information

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