Dysport Side Effects

Generic name: abobotulinumtoxinA

Medically reviewed by Drugs.com. Last updated on Oct 16, 2024.

Note: This document provides detailed information about Dysport Side Effects associated with abobotulinumtoxinA. Some dosage forms listed on this page may not apply specifically to the brand name Dysport.

Applies to abobotulinumtoxinA: intramuscular powder for solution.

Precautions

It is very important that your doctor check your progress at regular visits. This will allow your doctor to see if the medicine is working properly and to decide if you should continue to receive it.

This medicine may cause serious allergic reactions, including anaphylaxis or serum sickness. These can be life-threatening and require immediate medical attention. Tell your doctor right away if you have a rash, itching, hoarseness, trouble breathing or swallowing, fever, joint swelling, muscle aches, or any swelling of your hands, face, or mouth after using this medicine.

Serious muscle reactions have occurred within hours to weeks after receiving this medicine. If you start to have muscle weakness, loss of bladder control, or trouble with swallowing, talking, or breathing, call your doctor right away. In some patients, these problems could be life-threatening and may require immediate treatment in a medical facility.

This medicine may cause eye dryness when used in the treatment of glabellar lines. You may have reduced tear production, reduced blinking, and eye problems. Check with your doctor right away if eye pain or irritation, sensitivity of the eyes to sunlight, or other changes in vision occur during or after treatment. Your doctor may want your eyes be checked by an ophthalmologist (eye doctor).

This medicine may make your muscles weak and cause vision problems. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.

This medicine is made from donated human blood. Some human blood products have transmitted certain viruses to people who have received them, although the risk is low. Human donors and donated blood are both tested for viruses to keep the transmission risk low. Talk with your doctor if you have concerns about this risk.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.

Serious side effects of Dysport

Along with its needed effects, abobotulinumtoxinA (the active ingredient contained in Dysport) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur while taking abobotulinumtoxinA:

Other side effects of Dysport

Some side effects of abobotulinumtoxinA may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

For healthcare professionals

Applies to abobotulinumtoxinA: injectable powder for injection, intramuscular powder for injection.

General adverse events

The most commonly occurring side effects have included muscular weakness, dysphagia, dry mouth, injection site pain and discomfort, fatigue, headache, and nasopharyngitis.

Nervous system

• Very common (10% or more): Dysphonia (up to 28%), headache (11%), facial paresis (up to 11%)
• Common (1% to 10%): Dizziness, convulsion, syncope, hypoesthesia, partial seizures^[Ref]

Cardiovascular

• Common (1% to 10%): Hypertension, peripheral edema^[Ref]

Gastrointestinal

• Very common (10% or more): Dysphagia (up to 39%), dry mouth (up to 39%)
• Common (1% to 10%): Nausea, diarrhea, constipation, vomiting, gastroenteritis^[Ref]

Genitourinary

• Common (1% to 10%): Urinary tract infection, blood present in urine^[Ref]

Hepatic

• Uncommon (0.1% to 1%): Abnormal liver function tests^[Ref]

Hypersensitivity

• Rare (less than 0.1%): Anaphylaxis, urticaria, soft tissue edema
• Postmarketing reports: Hypersensitivity reactions including anaphylaxis^[Ref]

Metabolic

• Frequency not reported: Blood triglycerides increased^[Ref]

Ocular

• Very common (10% or more): Eye disorders (e.g., vision blurred, diplopia, visual acuity reduced, eye pain, eyelid disorder, accommodation disorder, dry eye, eye pruritus) (up to 17%)
• Common (1% to 10%): Eyelid edema, eyelid ptosis
• Postmarketing reports: Photophobia^[Ref]

Local

• Very common (10% or more): Injection site discomfort (e.g., pain, bruising, hemorrhage, injection site erythema/hematoma) (up to 22%)
• Common (1% to 10%): Injection site pain^[Ref]

Respiratory

• Very common (10% or more): Nasopharyngitis (10%), upper respiratory infection (10%)
• Common (1% to 10%): Breathing difficulty, dyspnea, sinusitis, cough, pharyngitis, bronchitis, rhinitis, oropharyngeal pain^[Ref]

Musculoskeletal

• Very common (10% or more): Muscular weakness (up to 56%)
• Common (1% to 10%): Musculoskeletal pain, muscle atrophy, pain in extremity, back pain, wrist fracture
• Uncommon (0.1% to 1%): Gait disturbance, hypertonia
• Postmarketing reports: Amyotrophy^[Ref]

Immunologic

• Common (1% to 10%): Infection, influenza, neutralizing antibodies^[Ref]

Dermatologic

• Frequency not reported: Excessive granulation tissue, erythema^[Ref]

Other

• Very common (10% or more): Fatigue (12%)
• Common (1% to 10%): Fall, injury, contusion, ear infection, pyrexia
• Uncommon (0.1% to 1%): Sensation of heaviness
• Frequency not reported: Distant spread of toxin effects
• Postmarketing reports: Vertigo, burning sensation, hypoesthesia

Psychiatric

• Common (1% to 10%): Depression, insomnia^[Ref]

See also:

Frequently asked questions

• Dysport vs Botox: What's the difference?
• What is botulinum toxin used to treat?

Further information

Dysport side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer