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Avage Side Effects

Generic name: tazarotene topical

Medically reviewed by Last updated on Apr 21, 2022.

Note: This document contains side effect information about tazarotene topical. Some of the dosage forms listed on this page may not apply to the brand name Avage.


Common side effects of Avage include: burning sensation, desquamation, erythema of skin, and xeroderma. See below for a comprehensive list of adverse effects.

For the Consumer

Applies to tazarotene topical: topical cream, topical gel

Side effects include:

In patients with psoriasis: Pruritus, erythema, burning/stinging, worsening of psoriasis, irritation, skin pain.

In patients with acne: Desquamation, burning/stinging, dry skin, erythema, pruritus.

In patients treated for photoaging: Desquamation, erythema, burning, dry skin, skin irritation, pruritus.

For Healthcare Professionals

Applies to tazarotene topical: topical cream, topical foam, topical gel, topical lotion


Very common (10% or more): Desquamation (29%), dry skin (27%), erythema (21%), burning sensation (14%)

Common (1% to 10%): Pruritus, irritation, nonspecific rash, irritant contact dermatitis, skin pain, worsening of psoriasis, stinging sensation, inflammation

Uncommon (0.1% to 1%): Cheilitis, excoriated skin, eczema, erythema sun-induced, papules, skin tightness, worsened acne

Postmarketing reports: Blister, dermatitis, urticaria, skin exfoliation, swelling at or near application sites, skin discoloration (including skin hyperpigmentation or skin hypopigmentation)[Ref]


Common (1% to 10%): Hypertriglyceridemia[Ref]


Common (1% to 10%): Facial pain[Ref]


Common (1% to 10%): Eyelid edema, eyelid irritation, eyelid inflammation[Ref]


Uncommon (0.1% to 1%): Infection[Ref]


Uncommon (0.1% to 1%): Pharyngitis[Ref]

Nervous system

Uncommon (0.1% to 1%): Headache, hypesthesia[Ref]

Frequently asked questions


1. "Product Information. Tazorac (tazarotene topical)." Allergan Inc (2001):

2. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

3. Cerner Multum, Inc. "Australian Product Information." O 0

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.