Avage Dosage

Assessment Prior to Treatment Initiation

Obtain a pregnancy test within 2 weeks prior to AVAGE Cream therapy. Initiate AVAGE Cream therapy during a menstrual period [see Contraindications (4), Warnings and Precautions (5.1), and Use in Specific Populations (8.1, 8.3)].

Carefully assess facial pigmented lesions of concern by a qualified physician (e.g., dermatologist) before application of AVAGE Cream [see Warnings and Precautions (5.4)].

Important Administration Instructions

Avoid accidental transfer of AVAGE Cream into eyes, mouth, or other mucous membranes. If contact with mucous membranes occurs, rinse thoroughly with water [see Warnings and Precaution (5.2)].

Wash hands thoroughly after application.

Emollients or moisturizers can be applied either before or after applying AVAGE Cream. However, ensure that the first cream or lotion has absorbed into the skin and has dried completely before subsequent cream or lotion application. Use facial moisturizers as frequently as desired [see Warnings and Precaution (5.2)].

AVAGE Cream is for topical use only. AVAGE Cream is not for ophthalmic, oral, or intravaginal use.

Use effective sunscreens and wear protective clothing while using AVAGE Cream [see Warnings and Precaution (5.3)].

Dosage and Administration Instructions

Remove any makeup before applying AVAGE Cream to the face. Dry the skin before applying the cream after face washing, bathing, or showering.

Apply a pea-sized amount once a day at bedtime to lightly cover the entire face, including the eyelids, if desired.

Wash hands thoroughly after application.