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Medications for Forehead Lines

Other names: Frown Lines; Glabellar Lines

About Forehead Lines: 

There are two main types of forehead lines. There are the furrows that run horizontally across the forehead, often with a dip or curve in the middle.  These lines or furrows are due to activity of the forehead muscle (frontalis muscle) which lifts the eyebrows when looking upwards and is also used to show facial expressions.  The other type of forehead line is the vertical lines between the eyebrows (glabella lines) which form when we are angry or concentrating, this is due to contracting of corrugator supercilii muscles and procerus muscles.

When the skin is younger the lines are dynamic, which means they are only present when the muscle are being used and then they disappear once the muscles relax.  As the skin ages the dynamic lines progress to become static lines, this means the lines are permanent and are present regardless of whether the muscles are contracting or not.

Lines and wrinkles are an effect of ageing on the skin and therefore have causes beyond our control for example individual genetics, gravity, medical skin conditions, pollution and stress.  Factors that can be managed to help reduce the effect of ageing are reducing sun exposure, not smoking, having a well balanced diet and good skin care.

Drugs Used to Treat Forehead Lines

The following list of medications are in some way related to, or used in the treatment of this condition.

Drug name Rx / OTC Pregnancy CSA Alcohol Reviews Rating Popularity
onabotulinumtoxinA C N Add review Rate

Generic name: onabotulinumtoxinA systemic

Brand name:  Botox Cosmetic

Drug class: skeletal muscle relaxants

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph

Botox Cosmetic C N Add review Rate

Generic name: onabotulinumtoxinA systemic

Drug class: skeletal muscle relaxants

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Jeuveau U Add review Rate

Generic name: prabotulinumtoxinA systemic

For consumers: dosage,

For professionals: AHFS DI Monograph, Prescribing Information

prabotulinumtoxinA U Add review Rate

Generic name: prabotulinumtoxinA systemic

Brand name:  Jeuveau

For consumers:

For professionals: A-Z Drug Facts, AHFS DI Monograph

Legend

Rx Prescription Only
OTC Over the Counter
Rx/OTC Prescription or Over the Counter
Off Label This medication may not be approved by the FDA for the treatment of this condition.
Pregnancy Category
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act (CSA) Schedule
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

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Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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