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User Reviews for Sulfamethoxazole / trimethoprim

Also known as: Bactrim, Bactrim DS, Bactrim IV, Bactrim Pediatric, Bethaprim, Bethaprim Pediatric, Co-trimoxazole, Cotrim, Cotrim DS, Cotrim Pediatric, Septra, Septra DS, Septra IV, SMZ-TMP DS, Sulfatrim, Sulfatrim Pediatric, Uroplus, Uroplus DS …show all brand names

The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care. Learn more about Sulfamethoxazole/trimethoprim.

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Condition Avg. Ratings Reviews Compare
Traveler's Diarrhea
9.0
   
1 review 75 medications
Acne
8.4
   
132 reviews 504 medications
Infection Prophylaxis
7.4
   
6 reviews 24 medications
Bronchitis
7.4
   
9 reviews 287 medications
Prevention of Bladder infection
6.3
   
5 reviews 29 medications
Otitis Media
5.9
   
7 reviews 137 medications
Bacterial Skin Infection
5.7
   
118 reviews 49 medications
Upper Respiratory Tract Infection
5.6
   
12 reviews 119 medications
Nocardiosis
5.5
   
1 review 21 medications
Kidney Infections
5.3
   
26 reviews 94 medications
Sinusitis
5.2
   
40 reviews 248 medications
Urinary Tract Infection
5.0
   
351 reviews 191 medications
Bacterial Infection
4.6
   
49 reviews 171 medications
Diverticulitis
4.5
   
1 review 32 medications
Prostatitis
4.0
   
20 reviews 48 medications
Summary of Sulfamethoxazole/trimethoprim reviews 6.0 778 reviews

Reviews for Sulfamethoxazole/trimethoprim

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For Prostatitis: "I took Bactrim for 28 days (along with 400mg Ibuprofen 2 x daily and a zinc/curcumin/resveratrol supplement 1 x daily. I had no side effects and symptoms GREATLY improved. Once the Bactrim was finished, I took 200mg Ibuprofen 2 x daily for the next week along with the supplement. I only gave Bactrim a "7" as I don't believe it would have worked alone to completely heal my prostate. I had to make dietary changes (no milk, more veggies/ greens and no caffeine/alcohol/ spicy foods) and take other things in combination with this medication."

   
7.0

JAY-C February 19, 2018

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Bactrim DS (sulfamethoxazole / trimethoprim) for Bacterial Skin Infection: "Absolutely the worst medication I've ever been on, and I've been on a lot. If an alternative is offered, take the alternative. Intense thirst, super awful anxiety (borderline paranoia), stomachaches and heartburn out the wazoo, night sweats, rash, dizziness, joint pain, loss of appetite were my symptoms (amongst others). Doc switched me to clindamycin. Not a single side effect! Symptoms gradually got better after dropping Bactrim."

   
1.0

Alex1234872 February 15, 2018

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Bactrim (sulfamethoxazole / trimethoprim) for Urinary Tract Infection: "I've taken this medication for both skin infections and (most recently) for a UTI. And it has now sent me to the hospital...for mental health. EXTREME anxiety to say the least. Pain in my sides, chest, shortness of breath, tremors all over my body. Felt like I was dying. Insisted doctors check my liver and kidneys for shutdown. Didn't eat a meal for a week (did try to at least eat a yogurt or 2 but that's all I could stomach) I was hospital-free for over a year...which is also the last time I took this med. If you have ANY history of mental health issues AVOID THIS DRUG!! I gave it a 2 because it DID clear up the infections. But was NOT worth the hospital copays, loss of work, etc!"

   
2.0

jennanne February 14, 2018

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Bactrim DS (sulfamethoxazole / trimethoprim) for Bacterial Skin Infection: "Never ever again will I take this medication. Ended up in ER with what they said was Cellulitis. Gave me Bactrim and Keflex to take. After taking the Bactrim just after one day headaches started. On day 4 I woke up and could not move any of my body as every muscle, joint, neck and head was so sore and aching. Went straight to urgent care and they took me off the antibiotics. Still having severe pains all over and I'm hoping it's just because the medication is still in my system. Seriously do not take this. There are plenty more antibiotics to take than this and going through this also."

   
1.0

Anonymous February 10, 2018

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Bactrim (sulfamethoxazole / trimethoprim) for Urinary Tract Infection: "I started the Bactrim prescription two days ago.... I was prescribed two pills a day for 7 days. You can feel the affects within hours and it’s not a great feeling if you have not had a sufficient meal. THIS MEDICATION DOES CAUSE FLU LIKE SYMPTOMS. I have only slept 2 hours total. This is hampering my studies and leaving me anxious. I have never had sleeping issues but here I am.........restless and very paranoid more than half of the night. The short amount of time that I do sleep, I have experienced awful nightmares.. very vivid and almost terrifying to the point of not wanting to blink. This medication is definitely a 0 in my book."

Kay_1243 February 9, 2018

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Bactrim (sulfamethoxazole / trimethoprim) for Urinary Tract Infection: "Have been taking it for 10 days for my UTI. No side effects whatsoever. Normally antibiotics make me super sick. This one is great and after two days my UTI was 100% better."

   
10

Anonymous February 9, 2018

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For Urinary Tract Infection: "C. koseri in urine culture Course: 480 mg 2x daily for 7 days It was a generic from Apotex called sulfatrim. Right away I have to ask, how difficult is it to coat the tablets in thin gelatin knowing that they are so irritating? They irritated my tongue, so I had to dip the tablets in olive oil before taking them. My stomach was on fire, letting acid and bile reach up to my throat. I quickly lost most of my appetite. However, 2 tablespoons of pepto bismol before each tablet (food alone never helped) solved this issue too. Lastly, there was neurotoxicity. Unfortunately, I am sensitive in this respect to many antibiotics. There is nothing to do about it. I had to manage through night sweats, insomnia, vivid dreams and weird perception of the world. At the same time the medication made me very relaxed, which was nice. After frank hallucinations on Clavulin, this did not make me worry much."

Tarragon83 (taken for less than 1 month) February 9, 2018

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For Sinusitis: "One pill in I felt dizzy, my skin was crawling and on fire. Second pill in I had headache, nauseous, no sleep, night sweats. Constant panicky feeling. Pill is going back on my “no thank you” list."

AFK (taken for less than 1 month) February 8, 2018

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SMZ-TMP DS (sulfamethoxazole / trimethoprim) for Urinary Tract Infection: "It helped my simple UTI almost immediately and completely but I had side effects that I've never experienced with any other drug. My face was extremely red (like a bright, painful red that felt like a bad sunburn) all over for the entire time, plus a week after I stopped taking it. I felt extremely anxious and jittery and I didn't get a good night of sleep for a week after I stopped this med. I should add that I had all these side effects when I only took the drug for 3 days! I've never experienced side effects with other antibiotics. I believe this is a sulfa containing drug and I guess I must have a sulfa allergy."

   
3.0

Reviewer99 (taken for less than 1 month) January 29, 2018

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Bactrim DS (sulfamethoxazole / trimethoprim) for Kidney Infections: "First time I took it I got a fever, chills and body aches. I called my doctor and requested a different antibiotic. Will never take Bactrim again!"

   
1.0

Anonymous (taken for less than 1 month) January 26, 2018

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Bactrim DS (sulfamethoxazole / trimethoprim) for Urinary Tract Infection: "I don't understand the bad reviews. I have been taking Bactrim since I was a kid, NEVER had a side effect and I had relieve RIGHT AWAY. UTI can cause nausea. Just take it with a lot of food & water and you be FINE!"

   
10

Uti- spooky January 25, 2018

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For Acne: "This medicine is like a magic pill ! I had just turned 20 when my clear skin started breaking out. I tried everything from antibiotics to spironolactone to changing my diet. But nothing worked, until I tried this medicine. Within four weeks my skin became so smooth and all the acne was gone. I did not experience any side effects except I got an initial breakout during week 1. I would highly recommend this for anyone who is at their last resort before accutane. But do your research because allergic reactions are associated with this medication."

   
10

ughal January 23, 2018

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For Urinary Tract Infection: "I was prescribed Bactrim for a UTI for 10 days twice a day. I noticed after taking the first pill, I would feel pressure near my lower abdomen area. The other sensation was feeling like I had a full bladder after the would pee but I guess that was part of the UTI. Throughout these days, I noticed a loss of appetite and a sense of depression. It’s day 10 and I noticed I lost 5 lbs. not sure if the UTI is gone since I took my last pill today and it gives me pain pressure near my abdomen so we’ll see."

   
5.0

ValleyWoman (taken for less than 1 month) January 16, 2018

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Bactrim (sulfamethoxazole / trimethoprim) for Bacterial Skin Infection: "Had a very hot and painful boil right on my belt line from shaving my pubic area. Went to the doc and he looked at it and said of the abscess was way too deep to Lance it put me on Bactroban ointment and high dose of Bactrim. After 2 days the infection started to clear up. As far as bactrim side effects not as bad as when I take penicillin mainly really bad headache, extreme thirst, frequent urination. Take probiotics at lunch to help with diarrhea"

   
8.0

Cliff clavin January 13, 2018

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Bactrim (sulfamethoxazole / trimethoprim) for Otitis Media: "This is the only medicine that is a miracle drug! I always use it for ear infection, sinus infection and bronchitis. I am allergic to penicillin and erythromycin. It works very quickly for me."

   
10

Eema53 January 6, 2018

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Sulfatrim (sulfamethoxazole / trimethoprim) for Bronchitis: "So, I had this antibiotic on hand for a UTI and I used it for an upper respiratory infection. I started getting white sores in my mouth and it has also made my lymph node under my chin swell, gave me massive headaches and extremely dry skin, very fatigued and just blah. I won't take it again. I stopped taking it. White sores are not as painful in my mouth and my lymph node is going down. Wow what a ride. Hope its better for you"

   
5.0

indigogirl (taken for less than 1 month) January 3, 2018

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Bactrim DS (sulfamethoxazole / trimethoprim) for Kidney Infections: "I always get digestive issues (severe nausea, diarrhea, gas, upset stomach) from antibiotics. I hadn't taken Bactrim before. For me the side effects have been very minimal. I eat a serving of carbs about 10 minutes before taking it (bread or pasta or a banana) and then drink a large glass of water with it, and have made sure to drink a lot of water generally. I'm also taking a probiotic midday. The side effects I've had are being more tired than usual, low appetite and a bit of a dull headache for a couple days. After the initial dose I had intense nausea but I had not eaten. I have one day remaining of the 7 days course. After one day on Bactrim my infection symptoms went away. I'll need a follow-up but so far, yay Bactrim!!"

   
9.0

Raj_1 January 2, 2018

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Bactrim DS (sulfamethoxazole / trimethoprim) for Bacterial Skin Infection: "I was prescribed Bactrim DS 800mg for 10 days after I had an infected abscess on my outer labia. I had incision/drainage and tested negative for herpes simplex, CT+NG DNA, MRSA, and staph. I went 8 days and noticed minor hand shakiness, a sunburn like itch/sting on my neck and collarbone and some right ab pain but didn’t think much of it. Day 9 happen and I wake up with a minor but expanding rash on my chest, neck, torso arms and legs. I went to ER and they said Bactrim allergic reaction, prescribed methylprenisolone steroid, and Hydroxyzine. 48 hrs since last dose of Bactrim lips are still dry, cracked and woke up with minor flat blood blister on inside of bottom lip. Is this still affecting me??"

Scared with symptoms (taken for less than 1 month) December 30, 2017

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For Bacterial Infection: "I was given this medication for a tooth infection under a crown. The next day I had awful neck and back pain. I went to the Chiropractor! The following day (day 3) I could not sleep for 5 nights because all my nerve endings were screaming in pain and I was almost hallucinating! The next night I was fine. It helped the tooth, then on Christmas night my body was extremely painful (even my breasts hurt). I saw white flashes and tossed to each side constantly. Extreme pain and I did not sleep at all! So I quit taking the Sulpha drug and went to the doctor 2 days later. They did all these blood tests and concluded I must be on the mend. I am still in extreme back pain 3 days after quitting the drug!"

   
1.0

Sadandhurting (taken for less than 1 month) December 28, 2017

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Bactrim DS (sulfamethoxazole / trimethoprim) for Bacterial Infection: "I've never experienced any side effects from antibiotics. But this stuff is scary. I took my second dose today and after 2 hrs I started to feel light headed, my heart started racing and a strong headache came on top of it. It is getting better now after 14 hrs. I refuse to take it any longer and let my body do the job."

   
4.0

vchri December 28, 2017

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For Bacterial Infection: "You won’t be hungry, you will feel full, but DRINK DRINK DRINK DRINK DRINK. Went through a gallon and a half in an hour on a full stomach. The symptoms are signs of dehydration. COFFEE = Bad idea, I promise that will make it worse. Stay away from high sodium foods as well, or keep drinking water until it’s bed time. I promise you, if every time you had a symptom and drink water, it will go away."

   
6.0

Listen carefully (taken for less than 1 month) December 26, 2017

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Bactrim DS (sulfamethoxazole / trimethoprim) for Urinary Tract Infection: "I was having some pretty bad UTI symptoms, so I went to my local urgent care and they gave me Bactrim. Oh my goodness worst medication I’ve ever taken!! I took only one dose at the urgent care. Went home and later that night, I’d say maybe 3-4 hours in. I was so nauseous. I finally got myself to sleep, to only wake up and vomit my guts out many times. Then I wasn’t able to eat for hours. It’s been about 3 days now since I haven’t taken any medication. And my stomach is still in pain, having nausea, gagging, and not able to eat quite the same. Stay away from this drug. It’s not good. It’s very bad for your stomach. Save yourself."

   
1.0

Brittany18 (taken for less than 1 month) December 22, 2017

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For Bacterial Skin Infection: "I was on Sulfamethoxazole-trimethoprim 800 mg-160 mg twice day and after 3rd day of taking it my lymph node was swollen on the back of my neck. Contacted my doctor and she asked me to continue my med. So I took it and within an hour my lips and face were swollen, shortness in breath , cold chill, whole body rashes and hives on my back. I was sent to the ER and injected steroid and received some IV to get the symptom controlled. I am still feeling very ill, still taking Benadryl every 6 hours to control the allergy, I have been in bed for 4 days now after ER. Be careful with this antibiotic because it has Sulfa in it which apparently I am allergic to"

   
1.0

Kedo December 20, 2017

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Bactrim (sulfamethoxazole / trimethoprim) for Bacterial Skin Infection: "I had what I thought was a boil on the back of my leg so I went to the E. R the worst pain of my life cutting it open I left they gave me bactrim omg I woke up with the worst headache my body dried out cause of the medicine. My lips cracked an bleed just by moving my lips, I went to a different E. R blood pressure is 181/164 I have shakes blurry vision, pain all over my body I have HIV and diabetes so I'm scared. They gave me tramadol and sent me home. I've got my husband writing this cause I'm so weak. So please doctors if you read this we know our bodies better then you and I should have been admitted but the only excuse is I might pick up another infection. I can do that being out in the open smh I feel like I'm dying an nobody is listening"

   
1.0

Very sick December 18, 2017

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Bactrim (sulfamethoxazole / trimethoprim) for Urinary Tract Infection: "I took Bactrim for 5 days, which resulted in two days of chest pain and a trip to the ER. After five days, I broke out in a rash from head to toe along with swelling of my face, lips, and throat. My mother was also allergic to sulfa medications. So, no more Bactrim for me."

Sulfa Allergy (taken for less than 1 month) December 15, 2017

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