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Medications for Acne

Other names: Acne Vulgaris; Blackheads; Breakouts; Cystic acne; Pimples; Whiteheads; Zits

What is Acne:  An inflammatory skin condition characterized by superficial skin eruptions around hair follicles.

Compare drugs associated with Acne

The following list of medications are in some way related to, or used in the treatment of this condition.

Drug name Rx / OTC Pregnancy CSA Alcohol Reviews Rating Popularity
doxycycline Rx D N X 496 reviews
7.0

Generic name: doxycycline systemic

Brand names:  Doryx, Vibramycin, Doxy 100, Monodox, Acticlate, Adoxa, Adoxa CK, Adoxa Pak, Adoxa TT, Avidoxy, Doxy 200, Mondoxyne NL, Morgidox, Ocudox, Oraxyl, Targadox, Vibra-Tabs

Drug class: tetracyclines, miscellaneous antimalarials

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
minocycline Rx D N 330 reviews
6.0

Generic name: minocycline systemic

Brand names:  Solodyn, Minocin, Cleeravue-M, Dynacin, Myrac, Ximino

Drug class: tetracyclines

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
spironolactone Off Label Rx C N X 229 reviews
7.0

Generic name: spironolactone systemic

Brand name:  Aldactone

Drug class: potassium-sparing diuretics, aldosterone receptor antagonists

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off Label: Yes

 
Aldactone Off Label Rx C N X 6 reviews
9.0

Generic name: spironolactone systemic

Drug class: potassium-sparing diuretics, aldosterone receptor antagonists

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

Off Label: Yes

 
clindamycin Rx B N 59 reviews
7.0

Generic name: clindamycin topical

Brand names:  Cleocin T, Clindagel, Clinda-Derm, Evoclin, Clindacin ETZ, Clindacin P, Clindacin PAC, ClindaReach Pledget, Clindets

Drug class: topical acne agents, vaginal anti-infectives

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
tretinoin Rx C N 302 reviews
7.0

Generic name: tretinoin topical

Brand names:  Retin-A, Retin A Micro, Atralin, Stieva-A, Avita, Stieva-A Forte

Drug class: topical acne agents

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
Bactrim Off Label Rx D N X 64 reviews
9.0

Generic name: sulfamethoxazole / trimethoprim systemic

Drug class: miscellaneous antibiotics, sulfonamides

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Off Label: Yes

 
Retin-A Rx C N 44 reviews
8.0

Generic name: tretinoin topical

Drug class: topical acne agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
Epiduo Rx C N 464 reviews
7.0

Generic name: adapalene / benzoyl peroxide topical

Drug class: topical acne agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
Aczone Rx C N 158 reviews
7.0

Generic name: dapsone topical

Drug class: topical acne agents

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

 
Differin Rx C N 115 reviews
7.0

Generic name: adapalene topical

Drug class: topical acne agents

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

 
isotretinoin Rx X N X 665 reviews
8.0

Generic name: isotretinoin systemic

Brand names:  Claravis, Absorica, Amnesteem, Myorisan, Zenatane, Sotret

Drug class: miscellaneous antineoplastics, miscellaneous uncategorized agents

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph

 
Solodyn Rx D N 87 reviews
7.0

Generic name: minocycline systemic

Drug class: tetracyclines

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
benzoyl peroxide Rx/OTC C N 26 reviews
8.0

Generic name: benzoyl peroxide topical

Brand names:  Acne Treatment, BenzEFoam, PanOxyl, Acetoxyl, Acne-10, Acne-Clear, Acnomel BP 5, Alquam-X Acne Therapy Gel, Benprox, Benzac, Benzac AC, Benzagel, Benzagel Wash, Benzashave, BenzEFoam Ultra, BenzePro, Benziq, Binora, BPO, BPO 3 Foaming Cloths, BPO 6 Foaming Cloths, BPO 9 Foaming Cloths, BPO Gel, BP Wash, Brevoxyl, Brevoxyl-4, Brevoxyl-8, Brevoxyl Acne Wash Kit, Brevoxyl Creamy Wash, Clearplex, Clearskin, Clinac BPO, Delos, Desquam-X Wash, EthexDERM BPW, Fostex BPO, Fostex Wash 10%, Inova, NeoBenz Micro, NeoBenz Micro SD, NeoBenz Micro Wash Plus Pack, Neutrogena Rapid Clear Stubborn Acne, Oscion, Oxy-10, Oxy Balance, Oxy Daily Wash, Pacnex, Peroderm 7 Wash, Persa-Gel, Riax, SE BPO, SoluCLENZ Rx, Triaz

Drug class: topical acne agents

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, Prescribing Information

 
Doryx Rx D N X 54 reviews
7.0

Generic name: doxycycline systemic

Drug class: tetracyclines, miscellaneous antimalarials

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
SMZ-TMP DS Off Label Rx D N X 3 reviews
7.0

Generic name: sulfamethoxazole / trimethoprim systemic

Drug class: miscellaneous antibiotics, sulfonamides

For consumers: dosage, interactions, side effects

Off Label: Yes

 
tetracycline Rx D N 17 reviews
8.0

Generic name: tetracycline systemic

Brand names:  Achromycin V, Ala-Tet, Brodspec, Panmycin, Sumycin, Tetracap, Tetracon

Drug class: tetracyclines

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
Tazorac Rx X N 9 reviews
8.0

Generic name: tazarotene topical

Drug class: topical antipsoriatics

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
Minocin Rx D N 11 reviews
7.0

Generic name: minocycline systemic

Drug class: tetracyclines

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
Septra Off Label Rx D N X 2 reviews
9.0

Generic name: sulfamethoxazole / trimethoprim systemic

Drug class: miscellaneous antibiotics, sulfonamides

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Off Label: Yes

 
Vibramycin Rx D N X 3 reviews
8.0

Generic name: doxycycline systemic

Drug class: tetracyclines, miscellaneous antimalarials

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
adapalene Rx C N 206 reviews
7.0

Generic name: adapalene topical

Brand name:  Differin

Drug class: topical acne agents

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
Bactrim DS Off Label Rx D N X 19 reviews
8.0

Generic name: sulfamethoxazole / trimethoprim systemic

Drug class: miscellaneous antibiotics, sulfonamides

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Off Label: Yes

 
Benzaclin Rx C N 58 reviews
8.0

Generic name: benzoyl peroxide / clindamycin topical

Drug class: topical acne agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
cephalexin Off Label Rx B N 3 reviews
6.0

Generic name: cephalexin systemic

Brand names:  Keflex, Biocef, Daxbia, Panixine

Drug class: first generation cephalosporins

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off Label: Yes

 
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Topics under Acne

Alternative treatments for Acne

The following products are considered to be alternative treatments or natural remedies for Acne. Their efficacy may not have been scientifically tested to the same degree as the drugs listed in the table above. However there may be historical, cultural or anecdotal evidence linking their use to the treatment of Acne.

Learn more about Acne

Legend

Off Label This medication may not be approved by the FDA for the treatment of this condition.
Prescription Only / Over the Counter
Rx Prescription Only
OTC Over the Counter
Rx/OTC Prescription or Over the Counter
Pregnancy
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act Schedule
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

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