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Spironolactone Drug Interactions

A total of 622 drugs (3104 brand and generic names) are known to interact with spironolactone.

  • 102 major drug interactions (402 brand and generic names)
  • 454 moderate drug interactions (2312 brand and generic names)
  • 66 minor drug interactions (390 brand and generic names)

Show all medications in the database that may interact with spironolactone.

Check for interactions with spironolactone

Type in a drug name and select a drug from the list.

Common medications checked in combination with spironolactone

spironolactone alcohol/food Interactions

There is 1 alcohol/food interaction with spironolactone

spironolactone disease Interactions

There are 7 disease interactions with spironolactone which include:

Drug Interaction Classification

The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No information available.

Do not stop taking any medications without consulting your healthcare provider.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.