Spironolactone Alternatives Compared
| Spironolactone | Doxycycline | Minocycline |
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| Spironolactone | Doxycycline | Minocycline |
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Spironolactone is a diuretic that may be used to remove excess fluid (edema) from the body, lower blood pressure, or treat hyperaldosteronism. It does not cause potassium loss from the body; however... View more |
Doxycycline is an effective antibiotic that treats a wide range of infections. However, it is not usually recommended for children aged less than eight nor in pregnant women in the last half of... View more |
Prescribed for Bacterial Infection, Acne, Bartonellosis, Actinomycosis, Bullous Pemphigoid, Brucellosis, Campylobacter Gastroenteritis, Cholera, Granuloma Inguinale, Meningitis - Meningococcal... View more |
Choose a suggestion below |
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| More about Spironolactone | More about Doxycycline | More about Minocycline | ||||||||||||||||||||||||
| Generic Status | ||||||||||||||||||||||||||
| Availability | ||||||||||||||||||||||||||
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Prescription only |
Prescription only |
Prescription only |
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| Ratings & Reviews | ||||||||||||||||||||||||||
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Spironolactone has an average rating of 7.1 out of 10 from a total of 630 ratings on Drugs.com. 62% of reviewers reported a positive effect, while 23% reported a negative effect. |
Doxycycline has an average rating of 6.5 out of 10 from a total of 1544 ratings on Drugs.com. 51% of reviewers reported a positive effect, while 26% reported a negative effect. |
Minocycline has an average rating of 5.9 out of 10 from a total of 552 ratings on Drugs.com. 45% of reviewers reported a positive effect, while 33% reported a negative effect. |
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| Drug Class | ||||||||||||||||||||||||||
| Side Effects | ||||||||||||||||||||||||||
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See the full spironolactone side effects document. |
See the full doxycycline side effects document. |
Commonly reported side effects include: headache. See the full minocycline side effects document. |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all spironolactone prices |
View all doxycycline prices |
View all minocycline prices |
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| Dosage Form(s) Available | ||||||||||||||||||||||||||
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| Brand Names | ||||||||||||||||||||||||||
| Aldactone, CaroSpir | Acticlate, Adoxa, Adoxa CK, Adoxa Pak, Adoxa TT, Alodox, Avidoxy, Doryx, Doryx MPC, Doxy 100, Doxy 200, Doxy-Caps, Doxy-D, LymePak, Mondoxyne NL, Monodox, Morgidox, Okebo, Oracea, Oraxyl, Targadox, Uracil, Vibramycin View more | Dynacin, Minocin, Minocin for Injection, Minolira, Solodyn, Ximino | ||||||||||||||||||||||||
| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||||||||||||||||||
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37 hours |
23 hours |
17.9 hours |
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| CSA Schedule** View glossary of terms | ||||||||||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||||||||||
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Category C
Risk cannot be ruled out
See the full Pregnancy Warnings document. |
Category D
Positive evidence of risk
See the full Pregnancy Warnings document. |
Category D
Positive evidence of risk
See the full Pregnancy Warnings document. |
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| Drug Interactions | ||||||||||||||||||||||||||
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A total of 357 drugs are known to interact with spironolactone:
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A total of 192 drugs are known to interact with doxycycline:
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A total of 190 drugs are known to interact with minocycline:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | ||||||||||||||||||||||||||
| First Approval Date | ||||||||||||||||||||||||||
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January 21, 1960 |
December 05, 1967 |
June 30, 1971 |
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| WADA Class View World Anti-Doping Agency classifications. | ||||||||||||||||||||||||||
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N/A |
N/A |
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| Related Treatment Guide | ||||||||||||||||||||||||||
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.