Doxycycline Interactions
There are 237 drugs known to interact with doxycycline, along with 3 disease interactions, and 2 alcohol/food interactions. Of the total drug interactions, 22 are major, 210 are moderate, and 5 are minor.
- View all 237 medications that may interact with doxycycline
- View doxycycline alcohol/food interactions (2)
- View doxycycline disease interactions (3)
Most frequently checked interactions
View interaction reports for doxycycline and the medicines listed below.
- Benadryl (diphenhydramine)
- Benadryl (diphenhydramine)
- CoQ10 (ubiquinone)
- CoQ10 (ubiquinone)
- Cymbalta (duloxetine)
- Cymbalta (duloxetine)
- Eliquis (apixaban)
- Eliquis (apixaban)
- Fish Oil (omega-3 polyunsaturated fatty acids)
- Fish Oil (omega-3 polyunsaturated fatty acids)
- Flonase (fluticasone nasal)
- Flonase (fluticasone nasal)
- Lyrica (pregabalin)
- Lyrica (pregabalin)
- Metoprolol Succinate ER (metoprolol)
- Metoprolol Succinate ER (metoprolol)
- Mucinex (guaifenesin)
- Mucinex (guaifenesin)
- Tylenol (acetaminophen)
- Tylenol (acetaminophen)
- Vitamin B12 (cyanocobalamin)
- Vitamin B12 (cyanocobalamin)
- Vitamin C (ascorbic acid)
- Vitamin C (ascorbic acid)
- Vitamin D3 (cholecalciferol)
- Vitamin D3 (cholecalciferol)
- Xanax (alprazolam)
- Xanax (alprazolam)
- Zyrtec (cetirizine)
- Zyrtec (cetirizine)
Doxycycline alcohol/food interactions
There are 2 alcohol/food interactions with doxycycline.
Doxycycline disease interactions
There are 3 disease interactions with doxycycline which include:
Report options
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Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Cephalexin
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Dexamethasone
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Metronidazole
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Metronidazole topical
Metronidazole topical is used for bacterial vaginosis, balanoposthitis, perioral dermatitis, rosacea
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
