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Doxycycline Patient Tips

How it works

Doxycycline is an antibiotic used to treat a wide range of infections. It belongs to a group of medicines known as tetracyclines.


Treats a wide range of infections such as those occurring in the respiratory tract, genitourinary area, sinuses, and on the skin.


If you are between the ages of 18 and 60, take no other medication or have no other medical conditions, side effects you are more likely to experience include:

  • May increase sun sensitivity exacerbating sunburn.
  • May cause nausea, diarrhea, a skin rash and other reactions.
  • Doxycycline, as with other tetracyclines, can cause permanent discoloration of the teeth (yellow-gray-brown staining) if used during tooth development (children up until the age of eight years) or the last half of pregnancy (affects the unborn baby's developing teeth). Doxycycline should be avoided in children under eight and pregnant women unless under exceptional circumstances.
  • Like other antibiotics, may rarely cause a serious type of diarrhea. Seek medical advice if this occurs.

Notes: In general, seniors or children, people with certain medical conditions (such as liver or kidney problems, heart disease, diabetes, seizures) or people who take other medications are more at risk of developing a wider range of side effects. For a complete list of all side effects, click here.

Bottom Line

Doxycycline is an effective antibiotic that treats a wide variety of infections; however, it is not usually recommended for children aged less than eight nor in pregnant women in the last half of pregnancy.


  • Avoid excessive sun exposure or artificial ultraviolet light while receiving doxycline; seek medical advice if skin redness or skin eruptions develop. Wear sun protective clothing and consider SPF50+ sun protection if exposure to sunlight is unavoidable.
  • Take exactly as directed and for the duration intended.
  • Only use when prescribed by a doctor to treat infections caused by susceptible bacteria as improper use increases the chance of resistant bacteria developing.
  • Seek medical advice if diarrhea develops, especially if it develops several weeks after discontinuing doxycycline.

Response and Effectiveness

  • Peak concentrations are reached within three hours after dosing; however, it may take up to 48 hours before infection-related symptoms start to abate.


Doxycycline [package insert]. Revised 12/2015. Lupin Pharmaceuticals, Inc. Accessed 02/2016

  • Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use doxycycline only for the indication prescribed.

  • Disclaimer: Every effort has been made to ensure that this information is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. This drug information does not endorse drugs, diagnose patients or recommend therapy. It is an informational resource designed as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. does not assume any responsibility for any aspect of healthcare administered with the aid of this information. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2017 Revision Date: 2016-02-18 00:00:00