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Humira User Reviews & Ratings

Humira has an average rating of 6.3 out of 10 from a total of 677 reviews on Drugs.com. 55% of reviewers reported a positive experience, while 32% reported a negative experience.

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Reviews for Humira

  • Mom...
  • Taken for 1 to 6 months
  • November 7, 2020

For Rheumatoid Arthritis "This drug should be taken off the market. My daughter had rheumatoid arthritis and had been taking Methotrexate along with other drugs. She was diagnosed with arthritis when she was in her early twenties, out of college. She started taking Humira last year, about 6 months into it. She died on April 18, 2020. All organs in her body had been compromised by this drug. She was 32 years old. When you take this, you are gambling with your life."

1 / 10
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  • Ann...
  • Taken for 10 years or more
  • January 1, 2019

For Rheumatoid Arthritis "I was diagnosed with Rheumatoid Arthritis in 1974. I was then 24 years old. Over the years I have been prescribed many different medications - various anti-inflammatory tablets, gold injections, Arava, Methotrexate etc. I have also had surgery on my hands, elbows, feet, and a replacement knee. I had many bad periods with pain, swelling, and stiffness - all the symptoms that are so well known to arthritis sufferers. But I had some good years also when I was able to go to work. In 2007, after a severe flare-up, I was prescribed Humira, 40mg every two weeks. The results are amazing. I haven’t had a flare up since I started using Humira. And apart from a bladder infection, quite rarely, I have had no problems. This year, now 2019, I will be on Humira 12 years and I think it is very good."

10 / 10
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207 Report
  • Cin...
  • Taken for 1 to 6 months
  • October 25, 2014

For Rheumatoid Arthritis "Humira gave me my life back! I received four different diagnoses by four different rheumatologists. Diagnoses: Fibromyalgia, Connective Tissue Disease, Rheumatoid Arthritis, and lastly Lupus. I used to have severe joint pain, mostly in my legs, difficulty walking long distances, inflammation, insomnia, depression, 60lb weight gain from steroids, stomach bloating, joint stiffness throughout the night. I would toss and turn throughout the night due to the stiff achy joint pain. My legs were the most achy, I would cry at night because the pain was so unbearable. I hated when it was time for bed because I knew pain would accompany sleep with stiffness. I felt like I was 90 years old. I was a 'Hot Mess!' Thank GOD for Humira!"

10 / 10
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Frequently asked questions

  • VRP...
  • Taken for 6 months to 1 year
  • March 4, 2019

For Rheumatoid Arthritis "My father started Humira, and within 7 months was diagnosed with lymphoma (cancer). He had an abdominal CT prior to starting Humira, and there was no growth or mass. A CT scan was done 7 months after starting Humira, and he had a massive abdominal growth and diagnosed with large B-cell diffuse lymphoma. His rheumatologist and oncologist both said to stop the Humira immediately, and his lymphoma was caused by Humira. He is currently on hospice. Please be advised that Humira absolutely does cause lymphoma in many people and is a dangerous medication."

1 / 10
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  • prv...
  • Taken for 1 to 6 months
  • February 7, 2020

For Rheumatoid Arthritis "My father went on Humira for rheumatoid arthritis. He was diagnosed with non-Hodgkin's lymphoma 6 months later, and his rheumatologist took him off Humira immediately. His rheumatologist admitted that Humira caused the lymphoma. My father died a few months later. There is a black box warning that Humira may cause lymphoma. This drug should be taken off the market! I tried calling the FDA and sent letters and information. No response from the FDA!"

1 / 10
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  • Hea...
  • November 14, 2019

For Hidradenitis Suppurativa "I want to share with you all that I had hidradenitis under my both arms for 2 years, and I completely cured it with an elimination diet. My problem was potatoes from the nightshade vegetables. You can search for elimination diet on Google and learn how it works. Don't forget about the nightshades: potatoes, eggplants, peppers, and tomatoes. I am 100% sure that an elimination diet will help you get rid of this disease, and you will be free from it forever. God bless."

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  • Anonymous
  • Taken for 1 to 6 months
  • July 26, 2012

For Rheumatoid Arthritis "I am 47 years of age and was diagnosed with rheumatoid arthritis at 28. I have been incapacitated every day since my diagnosis and for the last 3-5 years, I have had difficulty driving, walking, shopping, and leading a 'normal' life. This has led to a poor quality of life due to constant pain and depression. I started taking Humira about 8 weeks ago. One week after commencing, I woke up feeling very strange. It took me a few hours to work out I was completely pain-free. I hope it continues to be effective. It has changed my life completely."

10 / 10
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195 Report

More FAQ

  • Zap...
  • September 2, 2014

For Rheumatoid Arthritis "Diagnosed with seronegative rheumatoid arthritis about five years ago. It came on very quickly, and the pain was awful. Took methotrexate, but was quite ill from side effects. Thought I achieved remission and stopped methotrexate. Unfortunately, the disease was active, and I recently had a flare that has lasted for months. Blood work all negative. Rheumatologist ordered an MRI and found bone erosion in the wrists. Started Humira and had relief of symptoms shortly after. Just took the second injection. The nurse who instructed me on the shots said to leave it out of the refrigerator for 30 minutes, ice the site, and inject. I have done both injections in my stomach with no pain. Using the Humira pen. Also, I iced the spot for 5 minutes afterwards."

10 / 10
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  • Oce...
  • Taken for 1 to 6 months
  • March 12, 2016

For Ankylosing Spondylitis "I am 32, and as a child I was incredibly active. Around the age of 20, I started showing signs of AS, and was constantly in and out of the doctors, begging to be looked at. They shrugged me off as making it up: fibromyalgia, endometriosis, diabetes. It wasn't until at 25 that I was completely incapable of turning my head and had trouble walking that someone took me seriously. A specialist discovered I had AS. I only started Humira in December of 2015, a 40mg dose every 14 days. The morning after, I woke up and just lay there in shock. I hadn't felt like this since I was just a kid. I sat up in bed and just sobbed. I am so thankful for Humira every single day. I walk everywhere, I can skip up the steps. My neck may be permanently frozen, but I am hopeful."

9 / 10
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146 Report
  • Mar...
  • Taken for 1 to 2 years
  • January 19, 2021

For Rheumatoid Arthritis "At age 52, I began to experience symptoms (swelling, joint pain). After suffering for two months, I was diagnosed with rheumatoid arthritis in Feb 2019. I was put on prednisone for a few weeks and then began a weekly dose of methotrexate. After a few months of this treatment, my symptoms were slowly improving when my doctor decided to start me on Humira. I immediately began to feel better, well enough to resume living my active lifestyle, which includes running 40+ miles a week. Thankfully, any side effects have been minimal to date."

9 / 10
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79 Report
  • Too...
  • Taken for 1 to 2 years
  • January 6, 2016

For Rheumatoid Arthritis "At 23, my RA got so bad that walking and lifting my hands over my head was enough to make me wince in pain. Doc prescribed me Humira, and my pain went away overnight (literally). I continued taking it for a year, and I haven't had a single notable flare-up since the first injection. I still get random small aches, but they're completely forgettable. Can't say the list of long-term side effects doesn't scare me. So, since I feel 100%, I've decided I no longer want it. I have actually been off the med for about 6 months now and not a single flare-up. Doc pressured me to mix it with Methotrexate, but I'm not a human test subject so that ain't happening. Doctors, please listen to your patients. If they feel great, don't force more meds on them."

7 / 10
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  • How...
  • Taken for 2 to 5 years
  • February 5, 2019

For Rheumatoid Arthritis "I had sudden-onset acute rheumatoid arthritis at age 58. Severe pain, swelling, unable to work, or do much of anything. Rheumatologist put me on Humira after trying various other therapies. Was taking Methotrexate, but that started causing chest pain. The Humira was like magic for a while - the pain was much diminished. I was able to go back to work and resume a very active lifestyle. After about 1 1/2 years, the side effects started. Rash at first, then a plaque-like rash with sloughing skin (which is still spreading) on my head and hands. Then boils started - very large, very slow to heal. I have to stop taking it - it is killing my immune system. Really not sure how much damage has been done to my body from this drug. There are significant risks to this drug."

3 / 10
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  • Hum...
  • Taken for 1 to 6 months
  • August 12, 2019

For Ankylosing Spondylitis "Any negative ankylosing spondylitis experience I had before taking Humira was heaven compared to the awfulness Humira has caused me. There were zero positives for me while taking Humira. Even though I quit Humira a while ago, all of the negative symptoms Humira caused still continue. Now I have ankylosing spondylitis, daily headaches, extreme fatigue, constantly feel like I have the flu, way more back pain than before, constant vertigo, and psoriasis all over my scalp and jawline! I vomit a little bit in my mouth every time I see one of those ridiculous Humira commercials on TV. Humira was free for me thanks to the Canadian government and my insurance. I can’t imagine actually paying for this horrible drug. My heart goes out to anyone in the US that must pay out of pocket to play Russian roulette with their health by trying Humira. I wouldn’t use Humira again if someone paid me a million dollars! Absolutely the worst experience of my life."

1 / 10
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  • PBN...
  • Taken for 1 to 6 months
  • February 8, 2014

For Rheumatoid Arthritis "I had rheumatoid arthritis onset literally overnight in the wrist, and within a short period, all fingers, elbows, and shoulders. I have a negative RF but an elevated Sed Rate. I pushed my Rheumatologist hard to get in front of the disease progression. I was on Methotrexate alone for about 10 weeks, increasing dosage from 12.5mg to 17.5mg, but it had a marginal impact. I pushed for Humira, and within 48 hours after the first injection, I noticed improvement. I'm six weeks into combination therapy, and I'd say I'm 60-70% improved. Large joints are 90% better, but fingers remain stubborn. Yes, the shot hurts for 10 flipping seconds. I let it get to room temp for about 30-40 minutes...specialty pharmacist said that was fine. This medicine is awesome."

9 / 10
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  • Kir...
  • Taken for 1 to 2 years
  • March 9, 2013

For Psoriasis "It was hard for my mom to find a dermatologist in my area to start me on Humira because I was 14 years old. I was covered from head to toe, and my fingernails and toenails were so thick and painful. I had been suffering since the age of 3, and we had tried everything known to physicians and man. Finally, a dermatologist started me on two 40 mg shots per month. BAM! I was completely clear in 2 months. And I can honestly and wholeheartedly say that Humira has given me my life. I am now a thriving 16-year-old 10th grader. My grades have dramatically improved. I can write without pain. I can walk and wear shoes without pain. I had never worn a pair of shorts to school, and now I wear shorts and swim. Humira was a miracle for me and my family."

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153 Report
  • Reg...
  • Taken for less than 1 month
  • November 17, 2019

For Rheumatoid Arthritis "I've had RA after a bout of health issues, and finding out I had Pulmonary Fibrosis (PF) from unknown causes. I guess the shock and complications from a lung biopsy pushed my body over the edge. I was started on Prednisone and Sulfasalazine, but got minimal relief. Due to the PF, doctors were reluctant to try biological drugs. I did try Orencia, but had side effects. Was placed on Enbrel, but no relief. I finally got Humira. I took the first dose and felt strange the next day, panicked. By the next day, my life was in utter chaos. I did find that if you're on Benzos, it blocks them, so I was in total withdrawal. I had to research that one. 4 weeks later I'm dealing with horrible headaches, depression, vertigo, tinnitus. I just pray this med gets out of my system soon. I read it may take 88-98 days to clear. Never again. No more biological meds. Prayers for all who are suffering!"

1 / 10
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  • Anonymous
  • November 28, 2011

For Rheumatoid Arthritis "I take Humira for rheumatoid arthritis and so far it's the only medicine that works for me. I've tried Plaquenil and methotrexate but they don't even touch the pain/swelling. I began to feel relief the morning after the first shot of Humira. Don't let the instructions scare you. The shot is not painful. I let it stand on the counter 15 minutes before I give it so it's not so cold. My doctor suggested that I sit in a straight back chair so that the abdominal area is already pinched and you'll have both hands free, then pick a spot on my stomach that's 2 inches away from the navel and just do as the directions explain. You won't feel the needle, but the medication will burn just a little. I can't even say it hurts. Don't be afraid."

10 / 10
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154 Report
  • Anonymous
  • August 27, 2016

For Rheumatoid Arthritis "My mother was taking this drug twice monthly. She had been on it once before for about 2 years and had great results. She had to stop because of an operation. Later on, her arthritis caused so much pain, and she requested this medicine again. She took it for 3 months and was so happy to be able to get around. She then got scratched by her dog, took the shot, and by the next morning, she had a 104-degree fever, and infection spread throughout her body. She went into a coma state and never came out of it. She died from septic shock 6 days later. Use with extreme caution. Do not use if you even get a scratch or sore as it lowers your immune system and may cause death from an infection."

10 / 10
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109 Report
  • TJa...
  • August 3, 2020

For Ankylosing Spondylitis "It has been about a year for me taking Humira. I was actually quite concerned before starting it as I read all sorts of reviews claiming stuff like getting cancer and such, and I almost didn't take the drug out of fear. Having suffered from ankylosing spondylitis for a better part of 15 years and trying everything from different kinds of painkillers, muscle relaxants, chiropractors to months of physiotherapy, I had just learned to live with back pain and dreaded it every morning. Humira has been a miracle drug for me so far. I haven't had any pain whatsoever since the first two weeks of starting it. Blood work is all normal and haven't had any reactions or side effects other than some redness in the area where I inject it. The pain from injecting was also way exaggerated in the reviews. It is a little painful, but 5-10 seconds of light pain is nothing compared to the relief it provides."

10 / 10
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67 Report
  • RA ...
  • Taken for less than 1 month
  • September 15, 2013

For Rheumatoid Arthritis "I have had rheumatoid arthritis now for 7 years. It runs in my family, both grandmothers, my parents, and my 5 siblings. I have been taking methotrexate injections for 2 years, plus Celebrex and Plaquenil along with controlled pain medication. I thought, 'Is this the way my life is going to be, always in pain?' I started Humira about 3 weeks ago, and WOW, after the 1st injection, the next day I could not believe how much my pain and stiffness had decreased. I could actually get up by myself in the morning. I take my shot every 2 weeks. I start noticing about Friday or Saturday a little stiffness and feeling achy and know it's time for the next dose. I have experienced a lot of pain, burning, and stinging on the injection site. I have learned that what works for me is to lie down."

8 / 10
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  • Anonymous
  • Taken for 1 to 6 months
  • May 19, 2012

For Rheumatoid Arthritis "I was against taking this medication until my flare-ups were so bad I was not able to walk or use my arm. I am so grateful for this medication. I just had my 3rd dose (every other week). Other than the extreme pain during the shot and a bit unsettled for about 10 minutes after, I say this medication is a miracle. I am 99.75% pain free ~ the first time in over a year. So far no side effects other than very thirsty. Cutting down on coffee and have increased my water intake. I worry about possible future side effects but not being able to move is not living."

10 / 10
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140 Report
  • JBR...
  • Taken for 5 to 10 years
  • July 27, 2019

For Ankylosing Spondylitis "Was diagnosed with AS my last year in the Navy. My back was so bad that I could not walk normally (I had to walk like I had something shoved up my butt). They put me on Humira and I felt immediate relief. I was able to walk normally and even began running again. It’s been 5 years now, and I’ve gotten many colds but nothing serious. It allows mobility, which alleviates the pain. On no other meds so far besides acid reflux medicine. Very thankful, but still scared after every blood test. My quality of life has improved greatly."

8 / 10
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72 Report
  • Ana...
  • August 12, 2016

For Psoriatic Arthritis "I suffered from psoriasis for about 5 years and then started with severe pain in my fingers, then my wrists, elbows, shoulders, knees, and finally my toes. I had no idea what was wrong with me, and I literally thought I was dying. I was only 46 years old. I was finally diagnosed with psoriatic arthritis. I started Humira, and within 2 weeks, I was pain-free and have been since. I have been on Humira for over 2 years now. I have not suffered from any side effects at all. Humira also cleared up my skin about 90%, and the only symptom I still have from the PA is fatigue. Before Humira, I could not throw a football with my kids or catch a football, I was in so much pain. Now I can throw a ball, ride a bike, play basketball, whatever I want to do."

10 / 10
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96 Report
  • Rob...
  • September 19, 2016

For Ankylosing Spondylitis "My first injection was Friday. By Sunday morning, I felt like a weight was lifted off my shoulders. I felt no pain. NONE! As someone who is on their feet for 12 hours a day, I can't believe I can come home and play with my daughter again without wincing in pain and struggling to function after 7 pm. This is a miracle. The price of this drug is frustrating and I hope that may change over time, but if that is the price to pay to feel well, I'll deal with it. I hope this was informative."

10 / 10
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  • JC9...
  • March 31, 2015

For Ankylosing Spondylitis "I'm not one for hyperbole, but genuinely think it's a miracle. I've just had a proper good sneeze. Full inhalation, full 'James Brown' 'Owwww!' At the end. First time in over a year not been halted mid-sneeze by the pain of the inhalation or having had to control the sneeze to a mild 'heeewwwwww-Ouch.' Sounds ridiculous to those who've never felt that way, but in addition to the normal yada-yada-yada of being able to stand up and walk, etc., a proper sneeze or laugh or cough is priceless."

10 / 10
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104 Report
Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.