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User Reviews for Otezla

The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care. Learn more about Otezla.

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Condition Avg. Ratings Reviews Compare
Plaque Psoriasis
5.6
   
144 reviews 24 medications
Psoriatic Arthritis
5.2
   
74 reviews 67 medications
Summary of Otezla reviews 5.4 218 reviews

Reviews for Otezla

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For Psoriatic Arthritis "Was prescribed and took for 8 months for plaque psoriasis and psoriatic arthritis. After a month began to notice a big reduction in plaques but only mild relief in pain. After 4 months began to experience depressed feelings and random dark thoughts while nothing had changed in life circumstances. Decided to go off when scared myself with thoughts of crashing my vehicle while driving. However, be warned the psoriasis plaques is worse now than before I took the meds and the joint pain is back. Would not recommend."

   
3.0

StillSuffering478 February 18, 2018

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For Plaque Psoriasis "I have been taking Otezla for the months and I see absolutely no change at all and my plaque psoriasis seems to even gotten worse."

   
1.0

COCOTHECAT (taken for 1 to 6 months) February 7, 2018

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For Plaque Psoriasis "I’ve had plaque psoriasis on my scalp/right ear for less than one year. I’ve read many of the reviews here but I’m not letting the negatives discourage me from Otezla because some negative reviews could be from drug competitors and (since each person reacts differently to drugs) without knowing a person’s medical history or if they’re taking other drugs, there’s no way to be sure if their results/side-effects are a direct result of Otezla. So (while it’s good to know others experiences) don’t necessarily allow them to dictate your choice to try it (especially if your plaque psoriasis affects you like it affects me.) I have a history of headaches (mostly sinus), occasional depression, and irregular sleep patterns; however, the condition itself adds to my depression and sleep problems. It’s only been 7 days – no noticeable improvement but experiencing NO side-effects. I’m still positive and hopeful. I’ll continue posting updates!"

   
5.0

Cinderfnrella February 2, 2018

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For Psoriatic Arthritis "I have now been taking Otezla for 2 years. I have never had bad psoriasis, but psoriatic arthritis has affected me for about 5 years. It took me almost 9 months for my psoriatic arthritis saw any improvement. After 1 year of taking, I thought it was a wonder drug. I have had constant stomach and headache issues that I was willing to accept. I figured it wasn't as bad as having PsA. About 6 months ago it stopped working for me. I started experiencing pretty bad moods and felt like I was falling into depression. I have since moved on to a single dose at bed time. I recently started using CBD oil and it seems to be working pretty well. Worked for a while, but side effects were almost as bad as the condition."

   
4.0

Middleman12345 (taken for 2 to 5 years) January 17, 2018

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For Plaque Psoriasis "I'm writing this review bc I know how much I relied on them when I was trying to decide if I would start Otezla. I have only been on Otezla for 16 days. I am taking 30mg 2x a day...seems like maybe I skipped the starter pack? Headaches & nausea the first 2 weeks. Aspirin helps. Little bit of loose stools and loss of appetite but those have gone away by now. I have not experienced any depression. It does seems like my scalp is clearing up BUT my shins/legs are my big problem area, so far, I haven't seen much improvement on them.I will report back in April unless something awesome happens before then :) This lotion is great: First Aid Beauty: ULTRA REPAIR CREAM INTENSE HYDRATION"

   
5.0

KBonito January 16, 2018

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For Plaque Psoriasis "Thankfully I'm going back on Otezla tomorrow. After experiencing challenges with Methotrexate relative to liver issues, I started on Otezla about a year ago. As the result of a change in employment I changed employer provided health insurance. Unfortunately Anthem/Blue Cross refused to pay for the prescription and I was unable to continue with its use. My employer expanded health coverage on January 1st to include my previous health insurance provider. I have an appointment with my PCP tomorrow and I've been assured I can go back to using Otezla."

Anonymous (taken for 6 months to 1 year) January 2, 2018

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For Plaque Psoriasis "Since I have compromised immune systems ( HIV), Otezla, was the best choice, my dermatologist told me , and I started immediately, I have been taking strong medications for years, so I was willing to take unpleasant effects, well, it almost killed me, my toenails, my whole body, I became very irritated, violent, depressed, big crisis / I have been taken UV a, light treatments, every other day for months, trying to reversed the damage, only wandering, what's up inside me, what's coming next"

   
1.0

J. PUlido (taken for 1 to 2 years) December 31, 2017

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For Plaque Psoriasis "I am coming up on 2 months of using Otezla. So far I am thrilled with my results. Some of the the psoriasis spots have completely gone away others have faded and the white flaky buildup is gone. Winter is the really bad time for me and it looks better, a light pink. I had headaches and stress headaches the first 2/3 weeks and thought the pain was not worth it, but they went away. I also had loose stools and waking up a few times a night where I am completely awake for an hour or two. I have also had 2 colds this winter and I usually get 1 the entire season (not sure if related)."

   
9.0

SFSG (taken for 1 to 6 months) December 27, 2017

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For Plaque Psoriasis "Was on it for 2 years. It helped with the Psoriasis as well as the Psoriatic Arthritis in the beginning. After 6 months it stopped working. I went off, than back on so it would work. After Otezla decided not 2 pay anymore I went off 4 good. Now I have bowel problems."

   
3.0

GirlFlorda (taken for 1 to 2 years) December 26, 2017

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For Plaque Psoriasis "Started Otezla 2 wks ago. A few mild headaches but can’t be sure it was due to the drug. Interesting changes in skin on feet, hands, elbows & knees—less flakey, thinner. Feet itch like crazy later in the day and after evening shower even with non-toxic cleanser, warm water w/ cold water rinse. Hoping longer trial of this med will bring results."

38years (taken for less than 1 month) December 21, 2017

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For Psoriatic Arthritis "I was prescribed Otezla for psoriatic arthritis. I took it for about 18 weeks. My arthritis improved only minimally. - I experienced the side effects of nausea, diarrhea and headaches throughout the 18 weeks. I stopped the treatment since it wasn't really working for me. And that is where the real trouble began - I had only suffered mild psoriasis over the years. I have not had a significant outbreak in over 25 years. In very short order, after I stopped this medicine, my psoriasis returned with a vengeance!! It's now almost 6 months since I've stopped taking this drug and I'm STILL trying to get the psoriasis under control. I would NOT recommend anyone take this drug."

   
2.0

HodaMac December 18, 2017

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For Plaque Psoriasis "Have had psoriasis for 42 years, legs, arms, trunk. Afraid to take biologics because of side effects. Started Otezla and started clearing patches up on arms and trunk after 6 weeks, had light headaches and loose stools for couple weeks but subsided. I've been on it for 15 months and it's not clearing up any more if my skin. It seems stalled after starting out so well. I thought it was finally the miracle for psoriasis, but doesn't seem to be. The maker of Otezla actually pays for mine 100% and I have insurance that would not cover it at first but they will now."

   
5.0

Hey Mikey (taken for 1 to 2 years) December 10, 2017

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For Plaque Psoriasis "I have completed the Starter Pack week one. For 36 years, I have had psoriasis over my entire trunk, legs, arms, and feet. I have used phototherapy, creams, ointments, cortizone topical and tanning beds with very little relief. I am currently receiving Otezla free from Celgene. I have had NO side-effects to date, but my psoriasis has cleared from my entire body by 90%!! I have never had such clear skin in the last 36 years!! I am so grateful to this company for providing me with this wonder drug which my insurance would not cover! I know my results are not common, but I am thankful for each day that I am not miserable from this terrible affliction!"

Anonymous (taken for less than 1 month) December 3, 2017

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For Psoriatic Arthritis "I have been taking Otezla for psoriatic arthritis as well as psoriasis. At first I thought it was a miracle drug helping with the pain and the patches. I did have terrible (and I mean terrible) problems with my stomach. While it improved slightly, after a year and a half it still kills my stomach. I am going to get off of it because it stopped helping with the pain and my skin is worsening. I stuck with it despite the nonstop bowel movements (and headaches) because I thought it was helping, but now that I'm reverting back it isn't worth the nearly debilitating side effects."

Anonymous (taken for 1 to 2 years) November 30, 2017

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For Plaque Psoriasis "I'm 62 years old with a complicated medical history. I have chronic pain (RSD), Diabetes and now Plaque Psoriasis (mainly scalp). I began with Otezla starter pack increasing dose even slower than the pack. I've never had side effects but Otezla changed that. I had headaches, loose stool and stomach pains. My insurance denied paying and at $3000/month, I couldn't afford it. I stopped for two weeks and then got more samples. I used the starter pack dosing since I had already used Otezla. Big mistake. Stomach was on fire every time I ate. Stopped again for 2 weeks and restarted very slowly. Doing much better and its helping. However if insurance doesn't cover it, I have to stop. ¯\_(ツ)_/¯"

   
7.0

Markdoc55 November 13, 2017

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For Psoriatic Arthritis "I was diagnosed with HLA-B27 (a specific protein on your white blood cells that can be a sign of autoimmune disease) Dr told me I had Psoriatic Arthritis gave me a starter pack of Otezla took for 12 days , which all of stiffness and joint pain left, I am also on Phentermine and Topimirate for weight loss, so I didn’t experience any headache, however I did get somewhat depressed and no energy to do anything, I ran out of the starter pack had to get another but was off of it for 3 days, while off of it I noticed my mood was better and back to normal, but this morning oh my all my stiffness and pain are back so I am goin back on the new starter pack and try to deal with mood thing because this pain is crazy, I also do have a sinus head cold that I have had for 4 days but I kinda chalked that off to the time of year and weather!"

   
7.0

Kandi313 (taken for less than 1 month) November 13, 2017

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For Plaque Psoriasis "I have suffered from plaque psoriasis for 20 years. I have tried creams, biologics, etc. Nothing worked for long or it had severe side effects. After several years of no medical treatment, I contacted my dermatologist to see if there was something else to try. I'm so glad I did. My skin is 90% clear, the best it's looked in decades. Side effects are an upset stomach and loose stools. I make sure I take a dose with food and early in the day. If I take it too late in the day, I will not see sleep soundly."

   
9.0

TracySwaglione2002 November 11, 2017

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For Plaque Psoriasis "I have been taking Otezla for about 6 months, after about 6 years of Neotigason and various creams. The Neotigason can have side effects on the liver and requires constant monitoring via blood tests, with the result that I was often non compliant with horrible flare-ups of my moderate to bad plaque psoriasis. Now with Otezla, the outcome is fantastic, 98 percent clear up, with just light pink marks on forearms left. Scalp and face totally clear which is great. If I cut down on a dose, it comes back. Had the odd headache, loose stools, odd patch if insomnia. Can live with all of it. Biggest problem is the cost, extremely expensive, even after being subsidized here in Israel."

Topadvocate (taken for 6 months to 1 year) November 4, 2017

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For Plaque Psoriasis "I started September 1st 2017 with the starter pack. Had the usual symptoms that everyone is talking about. Toughed it out. Then the monthly dosage started after the starter pack finished. About the third and a half week I had pain in the lower left side of my stomach. I stopped the pill for a week. Pain was gone. So I thought lets try again. I then started the pill only in the evenings. Basically half dose. Since the start till now October 20 2017, my plaque psoriasis has been noticeably reduced. Halving the half (1 pill a day) dose has also calmed my usual symptoms. I am tempted to start back on 2 pills a day again."

   
6.0

Ralphus (taken for 1 to 6 months) October 23, 2017

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For Plaque Psoriasis "I am not happy. After taking the medication for a year without any effects (positive or negative) I stopped taking the medication. Why should I bother to take it if i did not have any reduction on psoriasis?"

   
2.0

olguta October 15, 2017

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For Plaque Psoriasis "Been on one month now and I'm now 75% clear which I can tolerate. The first few days did have slight nausea and diarrhea but nothing severe! No headaches, no sleep problems, no depression, and haven't had any more nausea or diarrhea. Has cleared scalp, legs, back and even nail psoriasis 100%. I'm only left with my stubborn spots on knees and elbows but the scaling and redness has improved greatly, only thin scales and slight discoloration left on those stubborn problem areas which I can live with. Happy with this drug and hope it continues!"

Anonymous242424242 (taken for 1 to 6 months) October 13, 2017

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For Plaque Psoriasis "I have had psoriasis since I was six years old (I am 22 now). My worst area has always been my scalp and elbows, with it extending to my torso, back, and legs. Recently I have been under stress and I'm overweight so my psoriasis is the worse it has ever been. My dermatologist decided on otezla. They warn you about the most common side effects: nausea and diarrhea. I experienced these symptoms within two days of starting the medication. I will say right away it started working, clearing my scalp first (which is the first area it tends to start working on). Now I am somebody who struggles with having diarrhea and can't deal with it emotionally. I had to stop the drug after only three weeks, which sucked because it was working amazing for me."

   
6.0

mdgdhdfg October 9, 2017

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For Plaque Psoriasis "After reading endless negativity reviews, I feel almost guilty to say how big a fan I am of Otezla. I developed mild to severe psoriasis around 33. Tried all the ointments, cortisone injections, laser and light treatment options with light/temporary relief. Started Otezla 1/1/17, had immediate positive results. Little nausea at first along with slight headache & bowel issues, all side effects subsided within a couple of weeks. Haven't lost any weight. Not depressed or sad. In fact, quite the opposite - due to clear skin/confidence I'm happier than I've been in years. I'm 99% clear! Never thought I'd be able to wear little shorts & be at the beach with clear skin again. Big fan & feel blessed. Hope this helped if you're on the fence"

   
9.0

Barbie0917 October 3, 2017

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For Plaque Psoriasis "Tried this med for 6 days; had to stop. Almost went crazy! Severe depression, cried at the drop of a hat, extremely nauseous, IBS & so irritable, it nearly cost my relationship!"

LuJean September 23, 2017

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For Plaque Psoriasis "I started with the starter pack, and when I went from 10 mg to 20 mg, it was a train wreck. I actually couldn't function, my entire body was like hell no... massive fatigue, cramping in the stomach, fogginess, couldn't go to work. I feel like I had 30 beers. I hope this works out for you if you are trying it, but I'm finished with this.gl"

   
1.0

Train Wreck1 September 19, 2017

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