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User Reviews for Otezla

The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care. Learn more about Otezla.

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Condition Avg. Ratings Reviews Compare
Plaque Psoriasis
5.7
   
134 reviews 23 medications
Psoriatic Arthritis
5.3
   
70 reviews 63 medications
Summary of Otezla reviews 5.5 204 reviews

Reviews for Otezla

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For Plaque Psoriasis "I'm 62 years old with a complicated medical history. I have chronic pain (RSD), Diabetes and now Plaque Psoriasis (mainly scalp). I began with Otezla starter pack increasing dose even slower than the pack. I've never had side effects but Otezla changed that. I had headaches, loose stool and stomach pains. My insurance denied paying and at $3000/month, I couldn't afford it. I stopped for two weeks and then got more samples. I used the starter pack dosing since I had already used Otezla. Big mistake. Stomach was on fire every time I ate. Stopped again for 2 weeks and restarted very slowly. Doing much better and its helping. However if insurance doesn't cover it, I have to stop. ¯\_(ツ)_/¯"

   
7.0

Markdoc55 November 13, 2017

1 users found this comment helpful.
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For Psoriatic Arthritis "I was diagnosed with HLA-B27 (a specific protein on your white blood cells that can be a sign of autoimmune disease) Dr told me I had Psoriatic Arthritis gave me a starter pack of Otezla took for 12 days , which all of stiffness and joint pain left, I am also on Phentermine and Topimirate for weight loss, so I didn’t experience any headache, however I did get somewhat depressed and no energy to do anything, I ran out of the starter pack had to get another but was off of it for 3 days, while off of it I noticed my mood was better and back to normal, but this morning oh my all my stiffness and pain are back so I am goin back on the new starter pack and try to deal with mood thing because this pain is crazy, I also do have a sinus head cold that I have had for 4 days but I kinda chalked that off to the time of year and weather!"

   
7.0

Kandi313 (taken for less than 1 month) November 13, 2017

2 users found this comment helpful.
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For Plaque Psoriasis "I have suffered from plaque psoriasis for 20 years. I have tried creams, biologics, etc. Nothing worked for long or it had severe side effects. After several years of no medical treatment, I contacted my dermatologist to see if there was something else to try. I'm so glad I did. My skin is 90% clear, the best it's looked in decades. Side effects are an upset stomach and loose stools. I make sure I take a dose with food and early in the day. If I take it too late in the day, I will not see sleep soundly."

   
9.0

TracySwaglione2002 November 11, 2017

3 users found this comment helpful.
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For Plaque Psoriasis "I have been taking Otezla for about 6 months, after about 6 years of Neotigason and various creams. The Neotigason can have side effects on the liver and requires constant monitoring via blood tests, with the result that I was often non compliant with horrible flare-ups of my moderate to bad plaque psoriasis. Now with Otezla, the outcome is fantastic, 98 percent clear up, with just light pink marks on forearms left. Scalp and face totally clear which is great. If I cut down on a dose, it comes back. Had the odd headache, loose stools, odd patch if insomnia. Can live with all of it. Biggest problem is the cost, extremely expensive, even after being subsidized here in Israel."

Topadvocate (taken for 6 months to 1 year) November 4, 2017

3 users found this comment helpful.
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For Plaque Psoriasis "I started September 1st 2017 with the starter pack. Had the usual symptoms that everyone is talking about. Toughed it out. Then the monthly dosage started after the starter pack finished. About the third and a half week I had pain in the lower left side of my stomach. I stopped the pill for a week. Pain was gone. So I thought lets try again. I then started the pill only in the evenings. Basically half dose. Since the start till now October 20 2017, my plaque psoriasis has been noticeably reduced. Halving the half (1 pill a day) dose has also calmed my usual symptoms. I am tempted to start back on 2 pills a day again."

   
6.0

Ralphus (taken for 1 to 6 months) October 23, 2017

4 users found this comment helpful.
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For Plaque Psoriasis "I am not happy. After taking the medication for a year without any effects (positive or negative) I stopped taking the medication. Why should I bother to take it if i did not have any reduction on psoriasis?"

   
2.0

olguta October 15, 2017

4 users found this comment helpful.
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For Plaque Psoriasis "Been on one month now and I'm now 75% clear which I can tolerate. The first few days did have slight nausea and diarrhea but nothing severe! No headaches, no sleep problems, no depression, and haven't had any more nausea or diarrhea. Has cleared scalp, legs, back and even nail psoriasis 100%. I'm only left with my stubborn spots on knees and elbows but the scaling and redness has improved greatly, only thin scales and slight discoloration left on those stubborn problem areas which I can live with. Happy with this drug and hope it continues!"

Anonymous242424242 (taken for 1 to 6 months) October 13, 2017

3 users found this comment helpful.
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For Plaque Psoriasis "I have had psoriasis since I was six years old (I am 22 now). My worst area has always been my scalp and elbows, with it extending to my torso, back, and legs. Recently I have been under stress and I'm overweight so my psoriasis is the worse it has ever been. My dermatologist decided on otezla. They warn you about the most common side effects: nausea and diarrhea. I experienced these symptoms within two days of starting the medication. I will say right away it started working, clearing my scalp first (which is the first area it tends to start working on). Now I am somebody who struggles with having diarrhea and can't deal with it emotionally. I had to stop the drug after only three weeks, which sucked because it was working amazing for me."

   
6.0

mdgdhdfg October 9, 2017

2 users found this comment helpful.
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For Plaque Psoriasis "After reading endless negativity reviews, I feel almost guilty to say how big a fan I am of Otezla. I developed mild to severe psoriasis around 33. Tried all the ointments, cortisone injections, laser and light treatment options with light/temporary relief. Started Otezla 1/1/17, had immediate positive results. Little nausea at first along with slight headache & bowel issues, all side effects subsided within a couple of weeks. Haven't lost any weight. Not depressed or sad. In fact, quite the opposite - due to clear skin/confidence I'm happier than I've been in years. I'm 99% clear! Never thought I'd be able to wear little shorts & be at the beach with clear skin again. Big fan & feel blessed. Hope this helped if you're on the fence"

   
9.0

Barbie0917 October 3, 2017

11 users found this comment helpful.
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For Plaque Psoriasis "Tried this med for 6 days; had to stop. Almost went crazy! Severe depression, cried at the drop of a hat, extremely nauseous, IBS & so irritable, it nearly cost my relationship!"

LuJean September 23, 2017

2 users found this comment helpful.
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For Plaque Psoriasis "I started with the starter pack, and when I went from 10 mg to 20 mg, it was a train wreck. I actually couldn't function, my entire body was like hell no... massive fatigue, cramping in the stomach, fogginess, couldn't go to work. I feel like I had 30 beers. I hope this works out for you if you are trying it, but I'm finished with this.gl"

   
1.0

Train Wreck1 September 19, 2017

4 users found this comment helpful.
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For Psoriatic Arthritis "Been on Otezzla for about 6 months. The first few months I thought my prayers had been answered. My skin cleared up by 75 percent in 3 months. I have psoriasis and psoriatic arthritis. My pain had decreased as well. I did have stomach issues, severe headaches and major pressure in my ears and can hardly hear! The medication has quit working. Not clearing up my scales or itching at all! And the pain! The pain in my fingers, elbows and feet is worse than ever. I'm up all during the night from joint pain, now have nerve pain in my feet and cannot open a bottle of water in the mornings. Very sad this didn't work out because I refuse to take immune suppression medication."

   
5.0

Denny789824 September 17, 2017

3 users found this comment helpful.
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For Psoriatic Arthritis "On otezla for a short time 4 weeks must come off it because of surgery right shoulder rotator cuff. Up to this point minor side effects but did cause some sleep issues which could also be contributed my upcoming surgery. Had such good results with Biologicals for 15 yrs. until they lost there effectiveness. Now as I get older 67 would like to try something less immunosuppressive. Not encouraged by comments I read. But everyone is different so I will stick it out for four months"

   
4.0

Mattcat (taken for 1 to 6 months) September 12, 2017

2 users found this comment helpful.
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For Plaque Psoriasis "I am just about to hit my 16th week of Otezla (which they say is about as long as it takes to start working). I am not noticing a massive improvement- some spots in certain areas are down to just pink inflamed dots (legs and torso), while other areas actually seem to be worse (elbows, ears, scalp). I found the first week or two I had a lot of loose bowel movements, and my appetite was suppressed, but that quickly went away. I cannot comment on headaches as I live with a neurological disorder. I have a drug plan through work, and luckily this drug is covered, so I will continue this drug until Christmas and then go from there."

hookings21 (taken for 1 to 6 months) September 10, 2017

1 users found this comment helpful.
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For Plaque Psoriasis "The very first day I took otezla it felt like I was going to vomit but I didn't so I continued taking it. Then after taking the second and third ones for the evening I started having pains on my right shoulder. I thought I slept funny. But the pain was still bearable and I thought it will go away so I continued taking it although I began having a hard time sleeping. The seventh day/evening it got worst. Right after I took the evening pill the pain on my right shoulder went all the way to my arms and my right fingers. I was up until 3 in the morning I couldn't sleep and thought of going to the urgent care. The next morning, both of my arms are in pain, I decided to stopped taking Otezla. I should have not taken it in the beginning."

   
1.0

biggest mistake September 8, 2017

7 users found this comment helpful.
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For Psoriatic Arthritis "I took Otezla twice, two years apart. My first experience helped my psoriasis and psoriatic arthritis within 3 months with minimal side effects. I had loose stool for a couple of days and a mild headache. THEN I developed a very aggressive breast cancer and was advised to stop Otezla.. I underwent chemotherapy, bilateral mastectomies and reconstruction. One year later, I began taking Otezla again because my psoriasis and PA came back with a vengeance, as predicted. Four months into treatment, I developed breast cancer in my sternum. Once again, I quit the Otezla and have since undergone radiation treatment. I did not tick the boxes for a patient at high risk for breast cancer. I feel my cancer may well have been a direct result of Otezla"

   
1.0

Joschally September 1, 2017

6 users found this comment helpful.
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For Plaque Psoriasis "I'm five days in and had to stop taking Otezla due to the horrible side effect from this drug. I'm having every side effects you could think of. Nausea, diarrhea, headache, vomiting, pain in my upper stomach so bad it was unbearable and chest pains. I haven't spoke to my rheumatologist yet but I choose on my own to stop taking this drug. Nothing helped for pain and I couldn't keep any good or liquids down. Joint pain as well as back pains started getting worse."

   
1.0

Anonymous (taken for less than 1 month) August 29, 2017

5 users found this comment helpful.
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For Plaque Psoriasis "This medicine is miracle to me. I have psoriasis from last 7 years. I tried all diff type of med from prescription to over the counter tablets and creams but nothing was working. I was getting depressed and anti social. For me it was looks like my Dr was just making money from me and not doing enough. I changed my dermatologist and got new one, then my new Doc prescribed me Otezla which I start taking twice a day sometime once a day. I seen my skin start getting clear. Today was the first day my hands was totally clear. I was so happy. I lost few pounds while I am taking this pills also I am more sexually active. Thanks to the creator of this pill!!"

Vaneet August 12, 2017

11 users found this comment helpful.
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For Plaque Psoriasis "Third and last day on Otezla. Took fourth 10mg pill at 6:30am with breakfast. Slight headache, no nausea, no depression. Not feeling myself. I had to make a conscious effort not to 'zone out' all day. BP is up. Had disturbing dreams last night and woke up with pain in hands, ankles, and back. Every plaque is itching like crazy. I have stopped taking this drug."

   
1.0

projectotezla August 11, 2017

6 users found this comment helpful.
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For Plaque Psoriasis "I am now on my eighth day ,and besides the slight nausea and the frequent bowel movements throughout the day (it's not affecting my working and taking care of my son's needs),I think that I'm going to stick it out. I was on the Enbrel sure click last year and because I caught an infection and my system was severely compromised, I was admitted to the hospital, in serious condition; so, no more Enbrel. I stayed clear for a few months after being taken off of it, but once the psoriasis came back ,it went rampant....please check back in a few weeks with an update"

   
4.0

MsT12171 (taken for less than 1 month) August 8, 2017

11 users found this comment helpful.
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For Plaque Psoriasis "This was for my Guttate Psoriasis; PROS: Easy to take and digest. No adverse side effects other than occasion so headache. CONS: Didn't really work. Improved flaming and dryness but red patches are still there and still itchy/burning skin. If you have mild psoriasis it may work but for anybody with moderate to severe I would be very doubtful. Let down as I was hoping it would be a wonder drug and it's definitely not. Some creams work better."

   
3.0

Aurastar56 (taken for 1 to 6 months) August 2, 2017

6 users found this comment helpful.
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For Psoriatic Arthritis "I took otezla for about 5 months for psoriatic arthritis. I experienced headaches and upper respiratory infections almost the entire time. I saw little, if any, improvement to my arthritis pain and inflammation."

   
1.0

Yandy (taken for 1 to 6 months) August 1, 2017

8 users found this comment helpful.
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For Psoriatic Arthritis "Since the first pill on Otezla I started to get severe sinus headaches that could not be remedied by Tylenol or Advil. Nasal congestion began shortly after that as did steady head pain. I am now 7 days on the pills and I stopping due to these headaches, loose bowel movements, sinus congestion and pain, headaches and most importantly INSOMNIA!! I have been up 2 days straight and have stopped these pills last night. Since being on these pills I have not slept more than 2 hrs per night if at all. My foot pain has been lessened as well as the pain in my fingers but the side effects are just not worth it. Still getting sharp pains in my toes and difficulty with hip joint and knees while I did not have before starting Otezla. Not the drug for me!"

cdep July 23, 2017

14 users found this comment helpful.
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For Plaque Psoriasis "I was on Humira for several years, and it worked great. Eventually though, my body started making antibodies against the Humira, and it started working with less efficacy. I then switched to Otezla. I once did a trial study of a pill version of a ps med (the only one I had ever heard of at the time), and it worked great, so I was pretty hopeful as I started Otezla. For me, I could literally feel the Humira leaving my body. For those of you with bad ps, I started feeling those pins and needles again. I gave Otezla almost 6 months before calling my Rheum doc and asking if I could try something else and here I am. I'm not scaling a ton, but I'm constantly itchy (hard to sleep). I've tried a lot and some have worked. For me, Otezla doesn't."

   
3.0

Big Jon 42 July 8, 2017

15 users found this comment helpful.
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For Psoriatic Arthritis "I am technically taking this for reactive arthritis, that I have struggled with on and off for 15 years. Most recently on a 4 year stint, where I have been talking steroids. The idea was that this would allow me to get off of steroids. It took a few months to seem to help, but now (6 months) I have been weening off the steroids. In the beginning I experienced migraines, which I never had before, about 2 per week, Now about 1 per month. I also regularly experience diarrhea, not having to go more often, but lose stool when I do. Annoying but tolerable. It also seems to work as an appetite suppressant, which is positive side effect for me at 40 yrs old lost about 8 lbs so far. So overall pretty good med now that migraines are less."

   
8.0

activatedvoxel July 7, 2017

13 users found this comment helpful.
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