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Medications for Plaque Psoriasis

Other names: Psoriasis vulgaris

About Plaque Psoriasis

Plaque psoriasis (psoriasis vulgaris) is the most common form of psoriasis. It is characterized by raised, inflamed, red lesions covered by a silvery white scale. It is typically found on the elbows, knees, scalp and lower back.

Drugs used to treat Plaque Psoriasis

The following list of medications are in some way related to, or used in the treatment of this condition.

Drug name Rating Reviews Activity ? Rx/OTC Pregnancy CSA Alcohol
Otezla 5.1 251 reviews
Rx C N

Generic name: apremilast systemic

Drug class: antirheumatics

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Humira 6.1 31 reviews
Rx B N

Generic name: adalimumab systemic

Drug class: antirheumatics, TNF alfa inhibitors

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Enbrel 8.4 14 reviews
Rx B N

Generic name: etanercept systemic

Drug class: antirheumatics, TNF alfa inhibitors

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Cosentyx 7.3 92 reviews
Rx B N

Generic name: secukinumab systemic

Drug class: interleukin inhibitors

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

betamethasone 9.5 5 reviews
Rx C N

Generic name: betamethasone topical

Brand name:  Sernivo

Drug class: topical steroids

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Taltz 7.3 98 reviews
Rx N

Generic name: ixekizumab systemic

Drug class: interleukin inhibitors

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Tremfya 7.9 15 reviews
Rx N

Generic name: guselkumab systemic

Drug class: interleukin inhibitors

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

apremilast 5.2 265 reviews
Rx C N

Generic name: apremilast systemic

Brand name:  Otezla

Drug class: antirheumatics

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph

betamethasone / calcipotriene 7.1 36 reviews
Rx C N

Generic name: betamethasone / calcipotriene topical

Brand names:  Taclonex, Enstilar, Taclonex Scalp, Wynzora …show all

Drug class: topical antipsoriatics

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, Prescribing Information

etanercept 8.4 14 reviews
Rx B N

Generic name: etanercept systemic

Brand names:  Enbrel, Erelzi, Eticovo

Drug class: antirheumatics, TNF alfa inhibitors

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph

adalimumab 6.1 31 reviews
Rx B N

Generic name: adalimumab systemic

Brand names:  Humira, Abrilada, Amjevita, Cyltezo, Hadlima, Hulio, Hyrimoz …show all

Drug class: antirheumatics, TNF alfa inhibitors

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

secukinumab 7.3 95 reviews
Rx B N

Generic name: secukinumab systemic

Brand name:  Cosentyx

Drug class: interleukin inhibitors

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph

Skyrizi 9.0 1 review
Rx N

Generic name: risankizumab systemic

Drug class: interleukin inhibitors

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Ilumya 5.0 2 reviews
Rx N

Generic name: tildrakizumab systemic

Drug class: interleukin inhibitors

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

ixekizumab 7.4 100 reviews
Rx N

Generic name: ixekizumab systemic

Brand name:  Taltz

Drug class: interleukin inhibitors

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph

Stelara 9.6 6 reviews
Rx B N

Generic name: ustekinumab systemic

Drug class: interleukin inhibitors

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Cimzia Rate Add review
Rx B N

Generic name: certolizumab systemic

Drug class: TNF alfa inhibitors

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

halobetasol Rate Add review
Rx C N

Generic name: halobetasol topical

Brand names:  Lexette, Bryhali

Drug class: topical steroids

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, Prescribing Information

guselkumab 7.9 15 reviews
Rx N

Generic name: guselkumab systemic

Brand name:  Tremfya

Drug class: interleukin inhibitors

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph

tazarotene 8.0 1 review
Rx X N

Generic name: tazarotene topical

Brand name:  Tazorac

Drug class: topical acne agents, topical antipsoriatics

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

ustekinumab 8.2 7 reviews
Rx B N

Generic name: ustekinumab systemic

Brand name:  Stelara

Drug class: interleukin inhibitors

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph

risankizumab 9.0 1 review
Rx N

Generic name: risankizumab systemic

Brand name:  Skyrizi

Drug class: interleukin inhibitors

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph

Tazorac 8.0 1 review
Rx X N

Generic name: tazarotene topical

Drug class: topical acne agents, topical antipsoriatics

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

tildrakizumab 5.0 2 reviews
Rx N

Generic name: tildrakizumab systemic

Brand name:  Ilumya

Drug class: interleukin inhibitors

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph

Taclonex 8.0 7 reviews
Rx C N

Generic name: betamethasone / calcipotriene topical

Drug class: topical antipsoriatics

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Legend

Rating For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).
Activity Activity is based on recent site visitor activity relative to other medications in the list.
Rx Prescription Only.
OTC Over the Counter.
Rx/OTC Prescription or Over the Counter.
Off-label This medication may not be approved by the FDA for the treatment of this condition.
EUA An Emergency Use Authorization (EUA) allows the FDA to authorize unapproved medical products or unapproved uses of approved medical products to be used in a declared public health emergency when there are no adequate, approved, and available alternatives.
Pregnancy Category
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act (CSA) Schedule
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

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Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.