Tildrakizumab Side Effects

Medically reviewed by Philip Thornton, DipPharm. Last updated on Sep 17, 2024.

Applies to tildrakizumab: subcutaneous solution.

Serious side effects of tildrakizumab

Along with its needed effects, tildrakizumab may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking tildrakizumab:

More common side effects

• body aches or pain
• chills
• cough
• difficulty in breathing
• ear congestion
• fever
• headache
• loss of voice
• nasal congestion
• runny nose
• sneezing
• sore throat
• unusual tiredness or weakness

Incidence not known

• itching skin
• large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or genitals

Other side effects of tildrakizumab

Some side effects of tildrakizumab may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common side effects

• bleeding, blistering, burning, coldness, discoloration of skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site
• diarrhea

Rare side effects

• dizziness
• pain in the arms and legs

For healthcare professionals

Applies to tildrakizumab: subcutaneous solution.

Hypersensitivity adverse events

• Frequency not reported: Hypersensitivity, angioedema, urticaria^[Ref]

Immunologic

• Very common (10% or more): Infections (e.g., upper respiratory tract infection) (23%)^[Ref]

Local

• Common (1% to 10%): Injection site reactions (e.g., injection site urticaria, pruritus, pain, reaction, erythema, inflammation, edema, swelling, bruising, hematoma, hemorrhage)^[Ref]

Respiratory

• Very common (10% or more): Upper respiratory tract infections (e.g., nasopharyngitis, upper respiratory tract infection, viral upper respiratory tract infection, pharyngitis) (14%)^[Ref]

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Further information

Tildrakizumab side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer