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Selective phosphodiesterase-4 inhibitors

Other names: PDE4

What are Selective phosphodiesterase-4 inhibitors?

Selective phosphodiesterase-4 inhibitors increase cyclic adenosine-3′,5′-monophosphate (cAMP) levels, resulting in a broad spectrum of anti-inflammatory effects in almost all inflammatory cells. Selective phosphodiesterase-4 inhibitors are used in the treatment of severe Chronic Obstructive Pulmonary Disease (COPD) to reduce the risk of COPD exacerbations. They are not bronchodilators and therefore not indicated for the relief of acute bronchospasm.

List of Selective phosphodiesterase-4 inhibitors

View by  Generic | Brand
Drug Name Avg. Rating Reviews
roflumilast systemic (Pro)
Brand name: Daliresp
7.1
 71 reviews
roflumilast topical (Pro)
Brand names: Zoryve, Zoryve Foam
8.7
 50 reviews
For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).

See also

Medical conditions treated or associated with selective phosphodiesterase-4 inhibitors:

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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